1-hydroxyanthraquinone (CAS 129-43-1) — formula C14H8O3, molecular weight 224.21; category organic chemicals.
| CAS Number | 129-43-1 |
|---|---|
| Molecular Formula | C14H8O3 |
| Molecular Weight | 224.21 |
| Melting Point | 193.8 °C |
| LogP | log Kow = 3.52 |
| Applications | Uses: Used to make dyes and pharmaceuticals, [HSDB], 1-Hydroxyanthraquinone can be used as an intermediate in the production of dyes and drugs., Methods of Manufacturing: A general method for synthesis of anthraquinones, including 1-hydroxy-anthraquinone, has been developed. The anthraquinones were obtained under mild conditions from ortho-dicarboxylic acid chlorides and suitable aromatic substrates via a FriedelCrafts process., 1-Hydroxyanthraquinone has been synthesized by diazotization of 1-aminoanthraquinone and heating the diazonium salt with concentrated sulfuric acid. After dilution with water, the precipitated crude product was diluted with acetone and purified by preparative thin-layer chromatography (TLC) in toluene:ethyl formate:formic acid (75:24:1)., 1-Hydroxyanthraquinone has also been prepared in 96.4% yield by reacting 1-nitroanthraquinone with sodium formate in dimethylformamide at 130 C for 17 hours., General Manufacturing Information: 9, 10-Anthracenedione, 1-hydroxy-: INACTIVE, 1-Hydroxyanthraquinone has been isolated from the roots of Rubia cordifolia, Morinda officinalis and Damnacanthus indicus, from the heartwood of Tabebuia avellanedae and the herb Cassia occidentalis. |
| Category | Organic Chemicals |
Documented applications: Uses: Used to make dyes and pharmaceuticals, [HSDB], 1-Hydroxyanthraquinone can be used as an intermediate in the production of dyes and drugs., Methods of Manufacturing: A general method for synthesis of anthraquinones, including 1-hydroxy-anthraquinone, has been developed. The anthraquinones were obtained under mild conditions from ortho-dicarboxylic acid chlorides and suitable aromatic substrates via a FriedelCrafts process., 1-Hydroxyanthraquinone has been synthesized by diazotization of 1-aminoanthraquinone and heating the diazonium salt with concentrated sulfuric acid. After dilution with water, the precipitated crude product was diluted with acetone and purified by preparative thin-layer chromatography (TLC) in toluene:ethyl formate:formic acid (75:24:1)., 1-Hydroxyanthraquinone has also been prepared in 96.4% yield by reacting 1-nitroanthraquinone with sodium formate in dimethylformamide at 130 C for 17 hours., General Manufacturing Information: 9, 10-Anthracenedione, 1-hydroxy-: INACTIVE, 1-Hydroxyanthraquinone has been isolated from the roots of Rubia cordifolia, Morinda officinalis and Damnacanthus indicus, from the heartwood of Tabebuia avellanedae and the herb Cassia occidentalis..
1-hydroxyanthraquinone is a carbon-based organic compound with CAS registry number 129-43-1 and molecular formula C14H8O3 (molecular weight 224.21), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 129-43-1
Its molecular formula C14H8O3 comprises 14 C, 8 H, 3 O atoms.
Also known as: 1-hydroxyanthraquinone · 1-羟基蒽醌
Category: organic chemicals
The CAS registry number of 1-hydroxyanthraquinone is 129-43-1.
Molecular formula C14H8O3, molecular weight 224.21.
It is also registered under: 1-hydroxyanthraquinone, 1-羟基蒽醌.
Recorded applications: Uses: Used to make dyes and pharmaceuticals, [HSDB], 1-Hydroxyanthraquinone can be used as an intermediate in the production of dyes and drugs., Methods of Manufacturing: A general method for synthesis of anthraquinones, including 1-hydroxy-anthraquinone, has been developed. The anthraquinones were obtained under mild conditions from ortho-dicarboxylic acid chlorides and suitable aromatic substrates via a FriedelCrafts process., 1-Hydroxyanthraquinone has been synthesized by diazotization of 1-aminoanthraquinone and heating the diazonium salt with concentrated sulfuric acid. After dilution with water, the precipitated crude product was diluted with acetone and purified by preparative thin-layer chromatography (TLC) in toluene:ethyl formate:formic acid (75:24:1)., 1-Hydroxyanthraquinone has also been prepared in 96.4% yield by reacting 1-nitroanthraquinone with sodium formate in dimethylformamide at 130 C for 17 hours., General Manufacturing Information: 9, 10-Anthracenedione, 1-hydroxy-: INACTIVE, 1-Hydroxyanthraquinone has been isolated from the roots of Rubia cordifolia, Morinda officinalis and Damnacanthus indicus, from the heartwood of Tabebuia avellanedae and the herb Cassia occidentalis..
Category: Organic Chemicals.
Independent reference data for 1-hydroxyanthraquinone (CAS 129-43-1), compiled from public chemistry databases.
| CAS Registry Number | 129-43-1 |
|---|---|
| PubChem CID | 8512 |
| Molecular formula | C14H8O3 |
| IUPAC name | 1-hydroxyanthracene-9,10-dione |
| UNII (FDA) | LFU129OE9H |
| Molecular Weight | 224.21 |
|---|---|
| XLogP3 | 3.5 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 0 |
| Exact Mass | 224.047344113 |
| Monoisotopic Mass | 224.047344113 |
| Topological Polar Surface Area | 54.4 |
| Heavy Atom Count | 17 |
| Melting Point | 193.8 °C |
|---|---|
| Solubility | In water, 8.5 mg/L @ 25 °C |
| Vapor Pressure | 0.00000021 [mmHg] |
| Vapor Pressure | 2.09X10-7 mm Hg @ 25 °C |
| LogP | log Kow = 3.52 |
| LogP | 3.52 |
1-HYDROXYANTHRAQUINONE; 129-43-1; 1-hydroxyanthracene-9,10-dione; 9,10-Anthracenedione, 1-hydroxy-; 1-Hydroxy-9,10-anthraquinone; Hydroxyanthraquinone; 1-Hydroxyanthrachinon; Anthraquinone, 1-hydroxy-; alpha-Hydroxyanthraquinone; LFU129OE9H; 1-hydroxy-9,10-anthracenedione; CHEBI:28877; NSC-8640; DTXSID1020722; RefChem:76013; DTXCID70722
| Reported hazard statements | H319 (100%), H351 (100%), H320 |
|---|
H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H351 (100%): Suspected of causing cancer [Warning Carcinogenicity]
1-hydroxyanthraquinone · CAS 129-43-1 · C14H8O3. UNII LFU129OE9H. Melting Point: 193.8 °C; Solubility: In water, 8.5 mg/L @ 25 °C; Vapor Pressure: 0.00000021 [mmHg].
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 1-羟基蒽醌