1,2-Naphthoquinone (CAS 524-42-5) — formula C10H6O2, molecular weight 158.15; category organic chemicals.
| CAS Number | 524-42-5 |
|---|---|
| Molecular Formula | C10H6O2 |
| Molecular Weight | 158.15 |
| Melting Point | 145-7 °C (decomp) |
| LogP | 1.5 |
| Applications | Uses: Used as a chemical reagent and intermediate, [Hawley] Used as a reagent for resorcinol and thalline, [Merck Index], Chemical reagent and intermediate, Methods of Manufacturing: Prepared by oxidation of 1-amino-2-naphthol with ferric chloride:..., by oxidation of naphthalene: Milas, US 2395638 (1946 to Research Corp.), by bacterial dissimilation of naphthalene:..., from tetrachloro-o-benzoquinone..., 1, 2-Naphthoquinone is obtained in 80% yield when 2-naphthol is oxidized by air in the liquid phase with copper(I) chloride as catalyst. Slightly lower yields are obtained when periodic acid and dimethyl formamide, iodosobenzene, or benzene seleninic anhydride is used as oxidant. A 95% yield can, however, be obtained with tetramethyloxopiperidinium chloride at low temperature. The quinone can also be obtained by the oxidation of 1-amino-2-hydroxynaphthalene hydrochloride with iron(III) chloride in hydrochloric acid., General Manufacturing Information: 1, 2-Naphthalenedione: INACTIVE |
| Category | Organic Chemicals |
Documented applications: Uses: Used as a chemical reagent and intermediate, [Hawley] Used as a reagent for resorcinol and thalline, [Merck Index], Chemical reagent and intermediate, Methods of Manufacturing: Prepared by oxidation of 1-amino-2-naphthol with ferric chloride:..., by oxidation of naphthalene: Milas, US 2395638 (1946 to Research Corp.), by bacterial dissimilation of naphthalene:..., from tetrachloro-o-benzoquinone..., 1, 2-Naphthoquinone is obtained in 80% yield when 2-naphthol is oxidized by air in the liquid phase with copper(I) chloride as catalyst. Slightly lower yields are obtained when periodic acid and dimethyl formamide, iodosobenzene, or benzene seleninic anhydride is used as oxidant. A 95% yield can, however, be obtained with tetramethyloxopiperidinium chloride at low temperature. The quinone can also be obtained by the oxidation of 1-amino-2-hydroxynaphthalene hydrochloride with iron(III) chloride in hydrochloric acid., General Manufacturing Information: 1, 2-Naphthalenedione: INACTIVE.
1,2-Naphthoquinone is a carbon-based organic compound with CAS registry number 524-42-5 and molecular formula C10H6O2 (molecular weight 158.15), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 524-42-5
Its molecular formula C10H6O2 comprises 10 C, 6 H, 2 O atoms.
Also known as: 1,2-Naphthoquinone · 1,2-萘醌
Category: organic chemicals
The CAS registry number of 1,2-Naphthoquinone is 524-42-5.
Molecular formula C10H6O2, molecular weight 158.15.
It is also registered under: 1,2-Naphthoquinone, 1,2-萘醌.
Recorded applications: Uses: Used as a chemical reagent and intermediate, [Hawley] Used as a reagent for resorcinol and thalline, [Merck Index], Chemical reagent and intermediate, Methods of Manufacturing: Prepared by oxidation of 1-amino-2-naphthol with ferric chloride:..., by oxidation of naphthalene: Milas, US 2395638 (1946 to Research Corp.), by bacterial dissimilation of naphthalene:..., from tetrachloro-o-benzoquinone..., 1, 2-Naphthoquinone is obtained in 80% yield when 2-naphthol is oxidized by air in the liquid phase with copper(I) chloride as catalyst. Slightly lower yields are obtained when periodic acid and dimethyl formamide, iodosobenzene, or benzene seleninic anhydride is used as oxidant. A 95% yield can, however, be obtained with tetramethyloxopiperidinium chloride at low temperature. The quinone can also be obtained by the oxidation of 1-amino-2-hydroxynaphthalene hydrochloride with iron(III) chloride in hydrochloric acid., General Manufacturing Information: 1, 2-Naphthalenedione: INACTIVE.
Category: Organic Chemicals.
Independent reference data for 1,2-Naphthoquinone (CAS 524-42-5), compiled from public chemistry databases.
| CAS Registry Number | 524-42-5 |
|---|---|
| PubChem CID | 10667 |
| Molecular formula | C10H6O2 |
| IUPAC name | naphthalene-1,2-dione |
| UNII (FDA) | 804K62F61Q |
| Molecular Weight | 158.15 |
|---|---|
| XLogP3 | 1.5 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 0 |
| Exact Mass | 158.036779430 |
| Monoisotopic Mass | 158.036779430 |
| Topological Polar Surface Area | 34.1 |
| Heavy Atom Count | 12 |
| Melting Point | 145-7 °C (decomp) |
|---|---|
| Density | 1.450 at 25 °C |
| Vapor Pressure | 0.000099 [mmHg] |
1,2-NAPHTHOQUINONE; 524-42-5; 1,2-Naphthalenedione; o-Naphthoquinone; beta-Naphthoquinone; 1,2-Naphthaquinone; 1,2-dihydronaphthalene-1,2-dione; ortho-naphthoquinone; 1,2-Dihydro-1,2-diketo-naphthalene; DTXSID2060171; NSC-9831; 804K62F61Q; CHEBI:34055; RefChem:412087; DTXCID6041189; 208-360-2
| GHS notification summary | 6.2% (3 / 48) |
|---|
| GHS notification summary | 6.2% (3 / 48) |
|---|---|
| Reported hazard statements | H302 (89.6%), H315 (93.8%), H319 (93.8%), H335 (91.7%) |
This chemical does not meet GHS hazard criteria for 6.2% (3 of 48) of reports.
H302 (89.6%): Harmful if swallowed [Warning Acute toxicity, oral]
1,2-Naphthoquinone · CAS 524-42-5 · C10H6O2. UNII 804K62F61Q. Melting Point: 145-7 °C (decomp); Density: 1.450 at 25 °C; Vapor Pressure: 0.000099 [mmHg].
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 1,2-萘醌