Pirfenidone (CAS 53179-13-8) — formula C12H11NO, molecular weight 185.22; category pharmaceutical intermediates and APIs.
| CAS Number | 53179-13-8 |
|---|---|
| Molecular Formula | C12H11NO |
| Molecular Weight | 185.22 |
| Melting Point | 109 |
| LogP | 1.9 |
| Applications | Uses: MEDICATION, Methods of Manufacturing: Prepd by phenylation of 5-methyl-2-pyridinone: S.M. Gadekar, United States of American patent 3839364 (1974 to Affiliates Med. Res.)., By phytochemical rearrangement of N-phenyl-6-methylpyridinium-3-olate., Formulations, Preparations: Oral: capsules, 267 mg, Esbriet (InterMune) |
| Category | Pharmaceutical Intermediates |
Documented applications: Uses: MEDICATION, Methods of Manufacturing: Prepd by phenylation of 5-methyl-2-pyridinone: S.M. Gadekar, United States of American patent 3839364 (1974 to Affiliates Med. Res.)., By phytochemical rearrangement of N-phenyl-6-methylpyridinium-3-olate., Formulations, Preparations: Oral: capsules, 267 mg, Esbriet (InterMune).
Pirfenidone is a pharmaceutical intermediate or API compound with CAS registry number 53179-13-8 and molecular formula C12H11NO (molecular weight 185.22), belonging to the pharmaceutical intermediates and APIs segment of chemical raw materials.
CAS number: 53179-13-8
Its molecular formula C12H11NO comprises 12 C, 11 H, 1 N, 1 O atoms.
Also known as: Pirfenidone · 吡非尼酮
Category: pharmaceutical intermediates and APIs
The CAS registry number of Pirfenidone is 53179-13-8.
Molecular formula C12H11NO, molecular weight 185.22.
It is also registered under: Pirfenidone, 吡非尼酮.
Recorded applications: Uses: MEDICATION, Methods of Manufacturing: Prepd by phenylation of 5-methyl-2-pyridinone: S.M. Gadekar, United States of American patent 3839364 (1974 to Affiliates Med. Res.)., By phytochemical rearrangement of N-phenyl-6-methylpyridinium-3-olate., Formulations, Preparations: Oral: capsules, 267 mg, Esbriet (InterMune).
Category: Pharmaceutical Intermediates.
Independent reference data for Pirfenidone (CAS 53179-13-8), compiled from public chemistry databases.
| CAS Registry Number | 53179-13-8 |
|---|---|
| PubChem CID | 40632 |
| Molecular formula | C12H11NO |
| IUPAC name | 5-methyl-1-phenylpyridin-2-one |
| UNII (FDA) | D7NLD2JX7U |
| Molecular Weight | 185.22 |
|---|---|
| XLogP3 | 1.9 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 1 |
| Exact Mass | 185.084063974 |
| Monoisotopic Mass | 185.084063974 |
| Topological Polar Surface Area | 20.3 |
| Heavy Atom Count | 14 |
| Melting Point | 109 |
|---|
PIRFENIDONE; 53179-13-8; Esbriet; Pirespa; AMR-69; Pirfenidona; Pirfenidonum; 5-methyl-1-phenylpyridin-2-one; 2(1H)-Pyridinone, 5-methyl-1-phenyl-; 5-Methyl-1-phenyl-2(1H)-pyridone; AMR 69; DTXSID4045183; D7NLD2JX7U; NSC-748456; DTXCID2025183; CHEBI:32016
| Reported hazard statements | H302 (100%) |
|---|
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)
Pirfenidone · CAS 53179-13-8 · C12H11NO. UNII D7NLD2JX7U. Melting Point: 109.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 吡非尼酮