2-氨基-N-[2-(2,5-二甲氧基苯基)-2-羟乙基]乙酰胺单盐酸盐

Name: 2-氨基-N-[2-(2,5-二甲氧基苯基)-2-羟乙基]乙酰胺单盐酸盐
Brand: 济南圣和化工有限公司

CAS 3092-17-9C12H18N2O4MW 254.28

济南圣和化工有限公司现供应有机化学品——2-氨基-N-[2-(2,5-二甲氧基苯基)-2-羟乙基]乙酰胺单盐酸盐（CAS 3092-17-9），分子式 C12H18N2O4，分子量 254.28。本页理化参数仅供参考，实际常规纯度按批次COA提供(不公开发布)，以批次 COA 及订单确认为准，支持批量采购与长期供货协议。

产品概览

CAS号	3092-17-9
分子式	C12H18N2O4
分子量	254.28
熔点	200
LogP	-0.5
纯度	按批次COA提供(不公开发布)
包装	按订单/批次确认(不公开发布)
应用领域	有机化学品
类别	有机化学品

应用领域

有机化学品

2-氨基-N-[2-(2,5-二甲氧基苯基)-2-羟乙基]乙酰胺单盐酸盐在有机化学品领域使用广泛。采购前请确认纯度等级与包装形式，以批次 COA 为验收依据。

包装与储存

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

运输常规化工运输

样品可协商提供

交期现货/按订单安排

供货能力：2-氨基-N-[2-(2,5-二甲氧基苯基)-2-羟乙基]乙酰胺单盐酸盐备有现货，包装形式为按订单/批次确认(不公开发布)。我们支持对公转账并开具增值税发票，山东省内可安排快速配送，省外按物流时效发货，具体请联系 info@591daili.com。

质量与文件

每批产品随货提供 COA（分析证书）；可按需提供 MSDS/技术数据表及第三方检测报告。纯度与包装以批次 COA 及订单确认为准。

关于供应商

作为化工原料供应服务商，济南圣和化工有限公司长期服务于化工贸易、食品添加、医药中间体、日化原料等行业的采购需求。除 2-氨基-N-[2-(2,5-二甲氧基苯基)-2-羟乙基]乙酰胺单盐酸盐外，您还可以在站内按 CAS 号或产品分类检索更多品类，获取规格与报价。

常见问题

2-氨基-N-[2-(2,5-二甲氧基苯基)-2-羟乙基]乙酰胺单盐酸盐的 CAS 号是多少？

2-氨基-N-[2-(2,5-二甲氧基苯基)-2-羟乙基]乙酰胺单盐酸盐的 CAS 号为 3092-17-9。

该产品的纯度和包装规格是什么？

常规纯度规格为按批次COA提供(不公开发布)，包装为按订单/批次确认(不公开发布)，随货提供 COA。

2-氨基-N-[2-(2,5-二甲氧基苯基)-2-羟乙基]乙酰胺单盐酸盐有什么用途？

主要应用于有机化学品。

如何购买或获取报价？

请发送邮件至 info@591daili.com 或通过 WhatsApp 联系，注明产品名称、CAS 号与需求数量，一个工作日内回复报价。供应商：济南圣和化工有限公司。

PubChem 公开数据

Description

2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide monohydrochloride · CAS 3092-17-9 · C12H18N2O4. UNII 6YE7PBM15H. Melting Point: 200; Melting Point: 150 °C; Melting Point: 200 - 203 °C.

Identification

CAS Registry Number	3092-17-9
PubChem CID	4195
Molecular formula	C12H18N2O4
IUPAC name	2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide
UNII (FDA)	6YE7PBM15H

Computed Descriptors

Molecular Weight	254.28
XLogP3	-0.6
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	6
Exact Mass	254.12665706
Monoisotopic Mass	254.12665706
Topological Polar Surface Area	93.8
Heavy Atom Count	18
Formal Charge	0

Physical & Chemical Properties

Melting Point	200
Melting Point	150 °C
Melting Point	200 - 203 °C
Solubility	4.45e+00 g/L
LogP	-0.5
LogP	0.1
Dissociation Constants	7.8

Physical description & handling notes

Solid
Soluble
Specific optical rotation = +138.5 deg at 20 °C/D (concentration = 0.5 in chloroform)
When heated to decomposition, material emits toxic fumes of nitrogen oxides and hydrogen chloride.
pKa = 7.8 (0.3% aqueous solution); pH 3.5 to 5.5 (5% aqueous solution) /Midodrine hydrochloirde/
159.5 Å² [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: TOXCAST; Source Identifier: DTXSID1047493]

GHS Hazard Classification

Reported hazard statements	H301 (97.6%)

H301 (97.6%): Toxic if swallowed [Danger Acute toxicity, oral]

P264, P270, P301+P316, P321, P330, P405, and P501 (click each P-code to see the statement)

Documented Uses

Use (kg; approx.) in Germany (2009): >10
Consumption (g per capita; approx.) in Germany (2009): 0.000122
Synthesized from hydroquinone dimethyl ether by Friedel-Crafts acylation with chloroacetyl chloride, amination to the corresponding 2-aminoacetophenone, acylation at the amino function with chloroacetyl chloride, displacement of the chloro by the azido group and finally reduction with, e.g., sodium borohydride and catalytic hydrogenation (Pd/C).
For the treatment of symptomatic orthostatic hypotension (OH).
FDA proposed to withdraw approval of the drug midodrine hydrochloride, used to treat the low blood pressure condition, orthostatic hypotension, because required post-approval studies that verify the clinical benefit of the drug have not been done. To date, neither the original manufacturer nor any generic manufacturer has demonstrated the drug's clinical benefit, for example, by showing that use of the drug improved a patient's ability to perform life activities.
...used as a vasoconstrictor agent in the treatment of hypotension

Synonyms

midodrine; 42794-76-3; Midodrin; Midodrina; Midodrinum; Midodrinum [INN-Latin]; St 1085; ST-1085; 1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol; DL-N1-(beta-Hydroxy-2,5-dimethoxyphenethyl)glycinamid; 6YE7PBM15H; Acetamide, 2-amino-N-(2-(2,5-dimethoxyphenyl)-2-hydroxyethyl)-; 2-Amino-N-(2,5-dimethoxy-beta-hydroxyphenethyl)acetamid; 2-Amino-N-(2,5-dimethoxy-beta-hydroxyphenethylacetamide; 2-Amino-N-(2,5-dimethoxy-beta-hydroxyphenethyl)acetamide; CHEBI:6933

Frequently Asked Questions

What are the CAS number and molecular formula of 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide monohydrochloride?

CAS 3092-17-9; molecular formula C12H18N2O4; molecular weight — g/mol.

What other names is 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide monohydrochloride known by?

midodrine, 42794-76-3, Midodrin, Midodrina, Midodrinum, Midodrinum [INN-Latin].

Is 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide monohydrochloride classified as hazardous?

Hazard statements reported: H301.

What are the key physical properties of 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide monohydrochloride?

Melting Point: 200; Melting Point: 150 °C; Melting Point: 200 - 203 °C; Solubility: 4.45e+00 g/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.