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6-氟-3-羟基吡嗪-2-甲酰胺

CAS 259793-96-9C5H4FN3O2MW 157.10

6-氟-3-羟基吡嗪-2-甲酰胺(CAS 259793-96-9)属有机化学品类产品,分子式 C5H4FN3O2,分子量 157.10。济南圣和化工有限公司常年现货供应该产品,常规纯度 按批次COA提供(不公开发布),可按客户需求安排分装包装,欢迎邮件或来电询价。

产品概览

CAS号259793-96-9
分子式C5H4FN3O2
分子量157.10
熔点187℃ to 193℃
LogP-0.6
纯度按批次COA提供(不公开发布)
包装按订单/批次确认(不公开发布)
应用领域有机化学品
类别有机化学品

应用领域

有机化学品

6-氟-3-羟基吡嗪-2-甲酰胺在有机化学品领域使用广泛。采购前请确认纯度等级与包装形式,以批次 COA 为验收依据。

包装与储存

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储存条件密封、阴凉干燥处保存
运输常规化工运输
样品可协商提供
交期现货/按订单安排

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常见问题

6-氟-3-羟基吡嗪-2-甲酰胺 的 CAS 号是多少?

6-氟-3-羟基吡嗪-2-甲酰胺 的 CAS 号为 259793-96-9。

该产品的纯度和包装规格是什么?

常规纯度规格为 按批次COA提供(不公开发布),包装为 按订单/批次确认(不公开发布),随货提供 COA。

6-氟-3-羟基吡嗪-2-甲酰胺 有什么用途?

主要应用于有机化学品。

如何购买或获取报价?

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PubChem 公开数据

Description

6-Fluoro-3-hydroxypyrazine-2-carboxamide · CAS 259793-96-9 · C5H4FN3O2. UNII EW5GL2X7E0. Melting Point: 187℃ to 193℃; Dissociation Constants: 5.1.

Identification

CAS Registry Number259793-96-9
PubChem CID492405
Molecular formulaC5H4FN3O2
IUPAC name5-fluoro-2-oxo-1H-pyrazine-3-carboxamide
UNII (FDA)EW5GL2X7E0

Computed Descriptors

Molecular Weight157.10
XLogP3-0.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Exact Mass157.02875454
Monoisotopic Mass157.02875454
Topological Polar Surface Area84.6
Heavy Atom Count11
Formal Charge0

Physical & Chemical Properties

Melting Point187℃ to 193℃
Dissociation Constants5.1

Physical description & handling notes

  • slightly soluble in water
  • Favipiravir functions as a prodrug and undergoes ribosylation and phosphorylation intracellularly to become the active favipiravir-RTP. Favipiravir-RTP binds to and inhibits RNA dependent RNA polymerase (RdRp), which ultimately prevents viral transcription and replication.

GHS Hazard Classification

Reported hazard statementsH302 (40%), H315 (60%), H319 (60%), H335 (60%), H341 (20%), H361 (40%)

H302 (40%): Harmful if swallowed [Warning Acute toxicity, oral]

H315 (60%): Causes skin irritation [Warning Skin corrosion/irritation]

Documented Uses

  • In 2014, favipiravir was approved in Japan to treat cases of influenza that were unresponsive to conventional treatment. Given its efficacy at targetting several strains of influenza, it has been investigated in other countries to treat novel viruses including Ebola and most recently, COVID-19.
  • Breast Feeding; Lactation; Milk, Human; Antiviral Agents
  • Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.
  • J - Antiinfectives for systemic use
  • J05 - Antivirals for systemic use
  • J05A - Direct acting antivirals

Synonyms

Favipiravir; 259793-96-9; 6-FLUORO-3-HYDROXYPYRAZINE-2-CARBOXAMIDE; avigan; T-705; 5-fluoro-2-oxo-1H-pyrazine-3-carboxamide; 6-fluoro-3-hydroxy-2-pyrazinecarboxamide; T 705; Fapilavir; EW5GL2X7E0; Favilavir; T-705 cpd; T705; DTXSID60948878; 2-Pyrazinecarboxamide, 6-fluoro-3-hydroxy-; CHEBI:134722

Frequently Asked Questions

What are the CAS number and molecular formula of 6-Fluoro-3-hydroxypyrazine-2-carboxamide?

CAS 259793-96-9; molecular formula C5H4FN3O2; molecular weight — g/mol.

What other names is 6-Fluoro-3-hydroxypyrazine-2-carboxamide known by?

Favipiravir, 259793-96-9, 6-FLUORO-3-HYDROXYPYRAZINE-2-CARBOXAMIDE, avigan, T-705, 5-fluoro-2-oxo-1H-pyrazine-3-carboxamide.

Is 6-Fluoro-3-hydroxypyrazine-2-carboxamide classified as hazardous?

Hazard statements reported: H302, H315, H319, H335, H341.

What are the key physical properties of 6-Fluoro-3-hydroxypyrazine-2-carboxamide?

Melting Point: 187℃ to 193℃; Dissociation Constants: 5.1.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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