2-Acetamidofluorene

Description

2-Acetamidofluorene · CAS 53-96-3 · C15H13NO. UNII 9M98QLJ2DL. Melting Point: 381 °F (NTP, 1992); Melting Point: 194 °C; Melting Point: 381 °F.

Identification

CAS Registry Number	53-96-3
PubChem CID	5897
Molecular formula	C15H13NO
IUPAC name	N-(9H-fluoren-2-yl)acetamide
UNII (FDA)	9M98QLJ2DL

Computed Descriptors

Molecular Weight	223.27
XLogP3	3.3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	1
Exact Mass	223.099714038
Monoisotopic Mass	223.099714038
Topological Polar Surface Area	29.1
Heavy Atom Count	17
Formal Charge	0

Physical & Chemical Properties

Melting Point	381 °F (NTP, 1992)
Melting Point	194 °C
Melting Point	381 °F
Vapor Pressure	0.00023 mmHg at 212 °F (NTP, 1992)
Vapor Pressure	0.00023 mmHg

Physical description & handling notes

• 2-acetylaminofluorene appears as white powder or light beige solid. (NTP, 1992)
• Tan, crystalline powder; [NIOSH]
• Tan, crystalline powder.
• Crystals from alcohol + water
• Tan, crystalline powder
• less than 1 mg/mL at 68.9 °F (NTP, 1992)

GHS Hazard Classification

Reported hazard statements	H302 (95.8%), H350 (94.4%)

Documented Uses

• 2-Acetylaminofluorene is frequently used in the laboratory by biochemists and technicians as a positive control in the study of liver enzymes and the carcinogenesis and mutagenicity of aromatic amines.
• Used in the study of liver enzymes and the carcinogenicity and mutagenicity of aromatic amines as a positive control. [HSDB]
• See 29CFR1910.1003 (Code of Federal Regulations pertaining to the manufacturing, processing, repackaging, releasing, handling, and storing of this chemical);
• As a positive control to study the carcinogenicity and mutagenicity of aromatic amines.
• Acetamide, N-9H-fluoren-2-yl-: ACTIVE
• Acetylaminofluorene is distributed by several companies that deal in specialty chemicals. Information obtained from these distributors indicates that acetylaminofluorene is imported from Europe. A typical chemical distributor keeps approx 9 lb of acetylaminofluorene in stock. The chemical is usually sold in 1, 5, or 25 g quantities. Based on this information, it is estimated that the total USA usage is less than 20 lb per year.

Synonyms

2-Acetamidofluorene; 53-96-3; N-(9H-Fluoren-2-yl)acetamide; 2-Acetylaminofluorene; N-2-Fluorenylacetamide; 2-AAF; N-acetyl-2-aminofluorene; Acetamide, N-9H-fluoren-2-yl-; 2-FAA; 2-(Acetylamino)fluorene; 2-Acetaminofluorene; 2-Fluorenylacetamide; 2-Acetoaminofluorene; N-9H-Fluoren-2-ylacetamide; Acetoaminofluorene; Azetylaminofluoren

Frequently Asked Questions

What are the CAS number and molecular formula of 2-Acetamidofluorene?

CAS 53-96-3; molecular formula C15H13NO; molecular weight — g/mol.

What other names is 2-Acetamidofluorene known by?

2-Acetamidofluorene, 53-96-3, N-(9H-Fluoren-2-yl)acetamide, 2-Acetylaminofluorene, N-2-Fluorenylacetamide, 2-AAF.

Is 2-Acetamidofluorene classified as hazardous?

Hazard statements reported: H302, H350.

What are the key physical properties of 2-Acetamidofluorene?

Melting Point: 381 °F (NTP, 1992); Melting Point: 194 °C; Melting Point: 381 °F; Vapor Pressure: 0.00023 mmHg at 212 °F (NTP, 1992).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.