7-乙基-10-羟基喜树碱

Name: 7-乙基-10-羟基喜树碱
Brand: 济南圣和化工有限公司

CAS 86639-52-3C22H20N2O5MW 392.4

济南圣和化工有限公司现供应有机化学品——7-乙基-10-羟基喜树碱（CAS 86639-52-3），分子式 C22H20N2O5，分子量 392.4。本页理化参数仅供参考，实际常规纯度按批次COA提供(不公开发布)，以批次 COA 及订单确认为准，支持批量采购与长期供货协议。

产品概览

CAS号	86639-52-3
分子式	C22H20N2O5
分子量	392.4
LogP	1.6
纯度	按批次COA提供(不公开发布)
包装	按订单/批次确认(不公开发布)
应用领域	有机化学品
类别	有机化学品

应用领域

有机化学品

7-乙基-10-羟基喜树碱主要应用于有机化学品。具体使用工况下的添加量与规格要求，欢迎与技术团队沟通确认。

包装与储存

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

运输常规化工运输

样品可协商提供

交期现货/按订单安排

采购提示：本产品按按订单/批次确认(不公开发布)起订发货，收到货物后请先核对包装完好性再行入库。储存条件为阴凉干燥、密封保存；如需 MSDS 或运输说明，可在询价时一并索取。

质量与文件

每批产品随货提供 COA（分析证书）；可按需提供 MSDS/技术数据表及第三方检测报告。纯度与包装以批次 COA 及订单确认为准。

关于供应商

作为化工原料供应服务商，济南圣和化工有限公司长期服务于化工贸易、食品添加、医药中间体、日化原料等行业的采购需求。除 7-乙基-10-羟基喜树碱外，您还可以在站内按 CAS 号或产品分类检索更多品类，获取规格与报价。

常见问题

7-乙基-10-羟基喜树碱的 CAS 号是多少？

7-乙基-10-羟基喜树碱的 CAS 号为 86639-52-3。

该产品的纯度和包装规格是什么？

常规纯度规格为按批次COA提供(不公开发布)，包装为按订单/批次确认(不公开发布)，随货提供 COA。

7-乙基-10-羟基喜树碱有什么用途？

主要应用于有机化学品。

如何购买或获取报价？

请发送邮件至 info@591daili.com 或通过 WhatsApp 联系，注明产品名称、CAS 号与需求数量，一个工作日内回复报价。供应商：济南圣和化工有限公司。

PubChem 公开数据

Description

7-Ethyl-10-hydroxycamptothecin · CAS 86639-52-3 · C22H20N2O5. UNII 0H43101T0J. LogP: 1.6.

Identification

CAS Registry Number	86639-52-3
PubChem CID	104842
Molecular formula	C22H20N2O5
IUPAC name	(19S)-10,19-diethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione
UNII (FDA)	0H43101T0J

Computed Descriptors

Molecular Weight	392.4
XLogP3	1.4
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	2
Exact Mass	392.13722174
Monoisotopic Mass	392.13722174
Topological Polar Surface Area	100
Heavy Atom Count	29
Formal Charge	0

Physical & Chemical Properties

LogP	1.6

GHS Hazard Classification

Reported hazard statements	H301 (75%), H341 (23.3%)

H301 (75%): Toxic if swallowed [Danger Acute toxicity, oral]

H341 (23.3%): Suspected of causing genetic defects [Warning Germ cell mutagenicity]

Documented Uses

Investigated for use/treatment in colorectal cancer.
Compounds that inhibit the activity of DNA TOPOISOMERASE I.
The entrapment of SN-38 in lipsomes results in a more stable and more soluble form of the drug. This allows for increased affinity of SN-38 to lipid membranes and improved delivery of the drug to tumor sites. SN-38 is a highly effective cytotoxic topoisomerase I inhibitor.

Synonyms

7-Ethyl-10-hydroxycamptothecin; 86639-52-3; SN-38; SN 38 lactone; SN 38; 10-Hydroxy-7-ethylcamptothecin; NK-012; 7-Ethyl-10-hydroxy-20(S)-camptothecin; NK 012; NK012; 0H43101T0J; CAMPTOTHECIN, 7-ETHYL-10-HYDROXY-; CHEBI:8988; DTXSID4040399; (4S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione; (4S)-4,11-diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

Frequently Asked Questions

What are the CAS number and molecular formula of 7-Ethyl-10-hydroxycamptothecin?

CAS 86639-52-3; molecular formula C22H20N2O5; molecular weight — g/mol.

What other names is 7-Ethyl-10-hydroxycamptothecin known by?

7-Ethyl-10-hydroxycamptothecin, 86639-52-3, SN-38, SN 38 lactone, SN 38, 10-Hydroxy-7-ethylcamptothecin.

Is 7-Ethyl-10-hydroxycamptothecin classified as hazardous?

Hazard statements reported: H301, H341.

What are the key physical properties of 7-Ethyl-10-hydroxycamptothecin?

LogP: 1.6.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.