2-巯基-1-甲基咪唑（CAS 60-56-0）：分子式 C4H6N2S、分子量 114.17。
| CAS号 | 60-56-0 |
|---|---|
| 分子式 | C4H6N2S |
| 分子量 | 114.17 |
| 熔点 | 143-146 °C |
| LogP | log Kow = -0.34 |
| 应用领域 | Uses: In cyanide-free silver electroplating. THERAP CAT: Antihyperthyroid.、Use (kg、approx.) in Germany (2009): >250、Use (kg) in USA (2002): 707、Consumption (g per capita、approx.) in Germany (2009): 0.00305、Consumption (g per capita) in the USA (2002): 0.00251、Calculated removal (%): 92.1、Use Classification: Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients、Pharmaceuticals、Methods of Manufacturing: PREPD BY TREATING AMINOACETALDEHYDE DIETHYL ACETAL WITH METHYL ISOTHIOCYANATE、FROM THIOCYANIC ACID & N-SUBSTITUTED AMINO ACETALS.、Formulations、Preparations: ...METHIMAZOLE、USP (1-METHYL-2-MERCAPTOIMIDAZOLE、TAPAZOLE)、MARKETED IN 5- & 10-MG TABLETS.、General Manufacturing Information: 2H-Imidazole-2-thione、1、3-dihydro-1-methyl-: ACTIVE |
登记用途：Uses: In cyanide-free silver electroplating. THERAP CAT: Antihyperthyroid.、Use (kg、approx.) in Germany (2009): >250、Use (kg) in USA (2002): 707、Consumption (g per capita、approx.) in Germany (2009): 0.00305、Consumption (g per capita) in the USA (2002): 0.00251、Calculated removal (%): 92.1、Use Classification: Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients、Pharmaceuticals、Methods of Manufacturing: PREPD BY TREATING AMINOACETALDEHYDE DIETHYL ACETAL WITH METHYL ISOTHIOCYANATE、FROM THIOCYANIC ACID & N-SUBSTITUTED AMINO ACETALS.、Formulations、Preparations: ...METHIMAZOLE、USP (1-METHYL-2-MERCAPTOIMIDAZOLE、TAPAZOLE)、MARKETED IN 5- & 10-MG TABLETS.、General Manufacturing Information: 2H-Imidazole-2-thione、1、3-dihydro-1-methyl-: ACTIVE。
2-巯基-1-甲基咪唑 是一种化工化合物，登记 CAS 号为 60-56-0，分子式 C4H6N2S（分子量 114.17）。
登记 CAS 号：60-56-0
其分子式 C4H6N2S 由 4 个碳、6 个氢、2 个氮、1 个硫 组成。
别名/同义词：2-巯基-1-甲基咪唑 · methimazole · 2-Mercapto-1-methylimidazole
2-巯基-1-甲基咪唑 的 CAS 登记号为 60-56-0。
分子式 C4H6N2S，分子量 114.17。
别名/同义词：2-巯基-1-甲基咪唑、methimazole、2-Mercapto-1-methylimidazole。
登记用途：Uses: In cyanide-free silver electroplating. THERAP CAT: Antihyperthyroid.、Use (kg、approx.) in Germany (2009): >250、Use (kg) in USA (2002): 707、Consumption (g per capita、approx.) in Germany (2009): 0.00305、Consumption (g per capita) in the USA (2002): 0.00251、Calculated removal (%): 92.1、Use Classification: Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients、Pharmaceuticals、Methods of Manufacturing: PREPD BY TREATING AMINOACETALDEHYDE DIETHYL ACETAL WITH METHYL ISOTHIOCYANATE、FROM THIOCYANIC ACID & N-SUBSTITUTED AMINO ACETALS.、Formulations、Preparations: ...METHIMAZOLE、USP (1-METHYL-2-MERCAPTOIMIDAZOLE、TAPAZOLE)、MARKETED IN 5- & 10-MG TABLETS.、General Manufacturing Information: 2H-Imidazole-2-thione、1、3-dihydro-1-methyl-: ACTIVE。
2-巯基-1-甲基咪唑（CAS 60-56-0）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 60-56-0 |
|---|---|
| PubChem CID | 1349907 |
| Molecular formula | C4H6N2S |
| IUPAC name | 3-methyl-1H-imidazole-2-thione |
| UNII (FDA) | 554Z48XN5E |
| Molecular Weight | 114.17 |
|---|---|
| XLogP3 | -0.3 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 0 |
| Exact Mass | 114.02516937 |
| Monoisotopic Mass | 114.02516937 |
| Topological Polar Surface Area | 47.4 |
| Heavy Atom Count | 7 |
| Melting Point | 143-146 °C |
|---|---|
| Melting Point | 146-148 °C |
| Melting Point | 146 °C |
| Solubility | 1.13e+01 g/L |
| LogP | log Kow = -0.34 |
| LogP | -0.2 |
| LogP | -0.22 |
methimazole; 60-56-0; thiamazole; Tapazole; 1-Methyl-1H-imidazole-2-thiol; Methimazol; 1-Methylimidazole-2-thiol; Mercazolyl; Thiamazol; Mercazole; Thymidazol; Thymidazole; Favistan; Mercaptazole; Metothyrine; Metazolo
| GHS notification summary | 1.8% (1 / 57) |
|---|
| GHS notification summary | 1.8% (1 / 57) |
|---|---|
| Reported hazard statements | H302 (17.5%), H317 (84.2%), H361 (80.7%) |
This chemical does not meet GHS hazard criteria for 1.8% (1 of 57) of reports.
H302 (17.5%): Harmful if swallowed [Warning Acute toxicity, oral]
2-Mercapto-1-methylimidazole · CAS 60-56-0 · C4H6N2S. UNII 554Z48XN5E. Melting Point: 143-146 °C; Melting Point: 146-148 °C; Melting Point: 146 °C.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: methimazole