维生素PP

Description

Vitamin PP · CAS 11032-50-1 · C6H6N2O. UNII 25X51I8RD4. Boiling Point: 302 to 320 °F at 760 mmHg (NTP, 1992); Boiling Point: 157; Boiling Point: BP: 157 °C at 5X10-4 atm.

Identification

CAS Registry Number	11032-50-1
PubChem CID	936
Molecular formula	C6H6N2O
IUPAC name	pyridine-3-carboxamide
UNII (FDA)	25X51I8RD4

Computed Descriptors

Molecular Weight	122.12
XLogP3	-0.4
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	1
Exact Mass	122.048012819
Monoisotopic Mass	122.048012819
Topological Polar Surface Area	56
Heavy Atom Count	9
Formal Charge	0

Physical & Chemical Properties

Boiling Point	302 to 320 °F at 760 mmHg (NTP, 1992)
Boiling Point	157
Boiling Point	BP: 157 °C at 5X10-4 atm
Melting Point	264 to 268 °F (NTP, 1992)
Melting Point	130
Melting Point	128.8 °C
Melting Point	130 °C
Melting Point	127-131 °C
Flash Point	182 °C
Solubility	500000

Physical description & handling notes

• Nicotinamide is a white powder. (NTP, 1992)
• Dry Powder
• Colorless needles or white crystalline powder. Bitter taste.
• Solid
• WHITE CRYSTALLINE POWDER.
• White, powder, needles from benzene

Regulatory Status

Regulatory & Food Contact	FDA Substance added to food: FLAVOR ENHANCER, FLAVORING AGENT OR ADJUVANT, NUTRIENT SUPPLEMENT CIR / INCI: Cosmetic ingredients (Niacinamide) -> CIR (Cosmetic Ingredient Review) CIR / INCI: Personal care product -> emollient -> amide
GHS notification summary	0.3% (3 / 1154)

GHS Hazard Classification

GHS notification summary	0.3% (3 / 1154)
Reported hazard statements	H315 (28.6%), H319 (99.6%), H335 (28.4%)

Documented Uses

• Nicotinamide is usually used to treat deficiency, because nicotinamide, unlike nicotinic acid (the most common form of niacin), does not cause flushing, itching, burning, or tingling sensations. [Merck Manual, p. 41]
• Nicotinamide is ... used in cosmetics as hair and skin conditioning agent.
• .../Has/ been used in the enrichment of bread, flour, and other grain-derived products. Animal feed is routinely supplemented with ... nicotinamide. Nicotinamide is also used in multivitamin preparations.
• Use (kg; approx.) in Germany (2009): >1000
• Consumption (g per capita; approx.) in Germany (2009): 0.0122
• Naturally produced by the body (endogenous).

Synonyms

nicotinamide; niacinamide; 98-92-0; 3-Pyridinecarboxamide; pyridine-3-carboxamide; Nicotinic acid amide; Aminicotin; Amixicotyn; Benicot; Dipegyl; Nicofort; Papulex; Nicotinic amide; Delonin amide; Pelonin amide; Inovitan PP

Frequently Asked Questions

What are the CAS number and molecular formula of Vitamin PP?

CAS 11032-50-1; molecular formula C6H6N2O; molecular weight — g/mol.

What other names is Vitamin PP known by?

nicotinamide, niacinamide, 98-92-0, 3-Pyridinecarboxamide, pyridine-3-carboxamide, Nicotinic acid amide.

What is the regulatory status of Vitamin PP?

Documented regulatory listings: FDA Substance added to food: FLAVOR ENHANCER, FLAVORING AGENT OR ADJUVANT, NUTRIENT SUPPLEMENT; CIR / INCI: Cosmetic ingredients (Niacinamide) -> CIR (Cosmetic Ingredient Review); CIR / INCI: Personal care product -> emollient -> amide.

Is Vitamin PP classified as hazardous?

0.3% of GHS notifications report no hazard classification (3 of 1154).

What are the key physical properties of Vitamin PP?

Boiling Point: 302 to 320 °F at 760 mmHg (NTP, 1992); Boiling Point: 157; Boiling Point: BP: 157 °C at 5X10-4 atm; Melting Point: 264 to 268 °F (NTP, 1992).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.