盐酸缬更昔洛韦

Description

Valganciclovir hydrochloride · CAS 175865-59-5 · C14H23ClN6O5. UNII 4P3T9QF9NZ.

Identification

CAS Registry Number	175865-59-5
PubChem CID	135413534
Molecular formula	C14H23ClN6O5
IUPAC name	[2-[(2-amino-6-oxo-1H-purin-9-yl)methoxy]-3-hydroxypropyl] (2S)-2-amino-3-methylbutanoate;hydrochloride
UNII (FDA)	4P3T9QF9NZ

Computed Descriptors

Molecular Weight	390.82
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	9
Exact Mass	390.1418455
Monoisotopic Mass	390.1418455
Topological Polar Surface Area	167
Heavy Atom Count	26
Formal Charge	0
Complexity	528

GHS Hazard Classification

Reported hazard statements	H340 (100%), H350 (77.8%), H351 (22.2%), H360 (88.9%), H372 (66.7%)

Documented Uses

• Valganciclovir hydrochloride is an antiviral prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of cytomegalovirus retinitis (CMV retinitis) in adults with AIDS. Valganciclovir hydrochloride is also FDA-approved for the prevention of CMV disease in recipients of organ transplants who are at risk for CMV diseases.
• CMV diseases, including CMV retinitis, can be opportunistic infections(OIs) of HIV.
• Antiviral (Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor)
• Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.
• DNA Polymerase Inhibitors [MoA]; Nucleoside Analog [EXT]; Nucleoside Analog Antiviral [EPC]; Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor [EPC]
• VALGANCICLOVIR HYDROCHLORIDE POWDER,

Synonyms

Valganciclovir hydrochloride; 175865-59-5; Valganciclovir HCl; Valcyte; Valcyt; DTXSID9046784; RS 079070-194; 4P3T9QF9NZ; RS-79070-194; NSC-760349; L-Valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester, hydrochloride (1:1); RO 107-9070/194; Ro107-9070/194; RS-079070-194; VALGANCICLOVIR (AS HYDROCHLORIDE); DTXCID7026784

Frequently Asked Questions

What are the CAS number and molecular formula of Valganciclovir hydrochloride?

CAS 175865-59-5; molecular formula C14H23ClN6O5; molecular weight — g/mol.

What other names is Valganciclovir hydrochloride known by?

Valganciclovir hydrochloride, 175865-59-5, Valganciclovir HCl, Valcyte, Valcyt, DTXSID9046784.

Is Valganciclovir hydrochloride classified as hazardous?

Hazard statements reported: H340, H350, H351, H360, H372.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.