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Description

Tasosartan · CAS 145733-36-4 · C23H21N7O. UNII 48G92V856H. Solubility: 3.25e-02 g/L.

Identification

CAS Registry Number	145733-36-4
PubChem CID	60919
Molecular formula	C23H21N7O
IUPAC name	2,4-dimethyl-8-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-5,6-dihydropyrido[2,3-d]pyrimidin-7-one
UNII (FDA)	48G92V856H

Computed Descriptors

Molecular Weight	411.5
XLogP3	3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	4
Exact Mass	411.18075832
Monoisotopic Mass	411.18075832
Topological Polar Surface Area	101
Heavy Atom Count	31
Formal Charge	0

Physical & Chemical Properties

Solubility	3.25e-02 g/L

Physical description & handling notes

• Solid
• By blocking the angiotensin II (AT1) receptor, the drug ultimately causes vasodilation, reduced secretion of vasopressin (ADH), reduced production and secretion of aldosterone, amongst other actions leading to the combined effect of a reduction of blood pressure.

Documented Uses

• Tasosartan is infrequently in the treatment of hypertension and heart failure.
• Agents that antagonize ANGIOTENSIN II TYPE 1 RECEPTOR. Included are ANGIOTENSIN II analogs such as SARALASIN and biphenylimidazoles such as LOSARTAN. Some are used as ANTIHYPERTENSIVE AGENTS.
• C09 - Agents acting on the renin-angiotensin system
• C09C - Angiotensin ii receptor blockers (arbs), plain
• C09CA - Angiotensin ii receptor blockers (arbs), plain
• QC09 - Agents acting on the renin-angiotensin system

Synonyms

TASOSARTAN; 145733-36-4; ANA-756; WAY-ANA-756; taso-sartan; ANA756; 48G92V856H; DTXSID40163148; 2,4-dimethyl-8-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-5,6-dihydropyrido[6,5-d]pyrimidin-7-one; tasosartanum; 2,4-dimethyl-8-((4-(2-(2H-tetrazol-5-yl)phenyl)phenyl)methyl)-5,6-dihydropyrido(6,5-d)pyrimidin-7-one; RefChem:891190; DTXCID3085639; C09CA05; 2,4-dimethyl-8-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-5,6-dihydropyrido[2,3-d]pyrimidin-7-one; CHEMBL432162

Frequently Asked Questions

What are the CAS number and molecular formula of Tasosartan?

CAS 145733-36-4; molecular formula C23H21N7O; molecular weight — g/mol.

What other names is Tasosartan known by?

TASOSARTAN, 145733-36-4, ANA-756, WAY-ANA-756, taso-sartan, ANA756.

What are the key physical properties of Tasosartan?

Solubility: 3.25e-02 g/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.