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Description

Sulconazole · CAS 61318-90-9 · C18H15Cl3N2S. UNII 5D9HAA5Q5S. Melting Point: 130ºC.

Identification

CAS Registry Number	61318-90-9
PubChem CID	5318
Molecular formula	C18H15Cl3N2S
IUPAC name	1-[2-[(4-chlorophenyl)methylsulfanyl]-2-(2,4-dichlorophenyl)ethyl]imidazole
UNII (FDA)	5D9HAA5Q5S

Computed Descriptors

Molecular Weight	397.7
XLogP3	6.1
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	6
Exact Mass	396.002153
Monoisotopic Mass	396.002153
Topological Polar Surface Area	43.1
Heavy Atom Count	24
Formal Charge	0

Physical & Chemical Properties

Melting Point	130ºC

Physical description & handling notes

• Slightly soluble
• 183.06 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 189.92 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

Documented Uses

• Sulconazole solution 1.0% is indicated for the treatment of tinea cruris and tinea corporis caused by _Trichophyton rubrum_, _Trichophyton mentagrophytes_, _Epidermophyton floccosum_, and _Microsporum canis_; and for the treatment of tinea versicolor. Effectiveness has not been proven in tinea pedis (athlete’s foot).
• Breast Feeding; Lactation; Milk, Human; Anti-Infective Agents; Antifungal Agents; Dermatologic Agents
• Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues.
• Established Pharmacologic Class [EPC] - Azole Antifungal
• Chemical Structure [CS] - Azoles
• Sulconazole is an Azole Antifungal.

Synonyms

sulconazole; 61318-90-9; Sulconazol; Sulconazolum; 1-[2-[(4-chlorophenyl)methylsulfanyl]-2-(2,4-dichlorophenyl)ethyl]imidazole; 5D9HAA5Q5S; DTXSID8044129; (+-)-1-(2,4-dichloro-beta-((p-chlorobenzyl)thio)phenethyl)imidazole; 1H-Imidazole, 1-(2-(((4-chlorophenyl)methyl)thio)-2-(2,4-dichlorophenyl)ethyl)-, (+-)-; 1-(2-(((4-CHLOROPHENYL)METHYL)THIO)-2-(2,4-DICHLOROPHENYL)ETHYL)-1H-IMIDAZOLE; 1-(2-((4-chlorophenyl)methylsulfanyl)-2-(2,4-dichlorophenyl)ethyl)imidazole; RefChem:56487; CHEBI:9325; DTXCID6024129; D01AC09; 1-(beta-(4''-chlorobenzylthio)-2'4'-dichlorophenethyl)imidazole

Frequently Asked Questions

What are the CAS number and molecular formula of Sulconazole?

CAS 61318-90-9; molecular formula C18H15Cl3N2S; molecular weight — g/mol.

What other names is Sulconazole known by?

sulconazole, 61318-90-9, Sulconazol, Sulconazolum, 1-[2-[(4-chlorophenyl)methylsulfanyl]-2-(2,4-dichlorophenyl)ethyl]imidazole, 5D9HAA5Q5S.

What are the key physical properties of Sulconazole?

Melting Point: 130ºC.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.