Sevoflurane

Description

Sevoflurane · CAS 28523-86-6 · C4H3F7O. UNII 38LVP0K73A. Boiling Point: 58.5; Boiling Point: 58.1-58.2 °C at 751 mm Hg; 585.5 °C at 760 mm Hg; Boiling Point: 58.5 °C.

Identification

CAS Registry Number	28523-86-6
PubChem CID	5206
Molecular formula	C4H3F7O
IUPAC name	1,1,1,3,3,3-hexafluoro-2-(fluoromethoxy)propane
UNII (FDA)	38LVP0K73A

Computed Descriptors

Molecular Weight	200.05
XLogP3	2.8
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	2
Exact Mass	200.00721185
Monoisotopic Mass	200.00721185
Topological Polar Surface Area	9.2
Heavy Atom Count	12
Formal Charge	0

Physical & Chemical Properties

Boiling Point	58.5
Boiling Point	58.1-58.2 °C at 751 mm Hg; 585.5 °C at 760 mm Hg
Boiling Point	58.5 °C
Melting Point	< 25 °C
Solubility	1.48e+00 g/L
Density	1505 at 25 °C/D
Vapor Pressure	157.0 [mmHg]
Vapor Pressure	VP: 200 torr at 25 °C; 160 torr
Vapor Pressure	193 mm Hg at 25 °C
LogP	2.4

Physical description & handling notes

• A clear, nonflammable colorless liquid with a non-irritating odor; [ACGIH TLVs and BEIs]
• Solid
• COLOURLESS LIQUID.
• Liquid
• Very slightly soluble
• Relative density of the vapour/air-mixture at 20 °C (air = 1): 1.1

GHS Hazard Classification

Reported hazard statements	H315 (44.7%), H319 (45.7%), H336 (56.4%), H361 (53.2%)

Documented Uses

• Used as an inhalation anesthetic; [ACGIH TLVs and BEIs]
• Use (kg) in Switzerland (2009): >2500
• Use (kg; approx.) in Germany (2009): >50000
• Consumption (g per capita) in Switzerland (2009): 0.32
• Consumption (g per capita; approx.) in Germany (2009): 0.61
• Consumption (g per capita) in the USA (2002): 0.57

Synonyms

sevoflurane; 28523-86-6; 1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane; Sevofluran; Ultane; Sevorane; Sevoflurano; Sojourn; MR6S4; sevoflo; Sevofluranum; Propane, 1,1,1,3,3,3-hexafluoro-2-(fluoromethoxy)-; Sevocalm; Petrem; MR-6S4; DTXSID8046614

Frequently Asked Questions

What are the CAS number and molecular formula of Sevoflurane?

CAS 28523-86-6; molecular formula C4H3F7O; molecular weight — g/mol.

What other names is Sevoflurane known by?

sevoflurane, 28523-86-6, 1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane, Sevofluran, Ultane, Sevorane.

Is Sevoflurane classified as hazardous?

Hazard statements reported: H315, H319, H336, H361.

What are the key physical properties of Sevoflurane?

Boiling Point: 58.5; Boiling Point: 58.1-58.2 °C at 751 mm Hg; 585.5 °C at 760 mm Hg; Boiling Point: 58.5 °C; Melting Point: < 25 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.