盐酸利匹韦林

Description

Rilpivirine hydrochloride · CAS 700361-47-3 · C22H19ClN6. UNII 212WAX8KDD.

Identification

CAS Registry Number	700361-47-3
PubChem CID	11711114
Molecular formula	C22H19ClN6
IUPAC name	4-[[4-[4-[(E)-2-cyanoethenyl]-2,6-dimethylanilino]pyrimidin-2-yl]amino]benzonitrile;hydrochloride
UNII (FDA)	212WAX8KDD

Computed Descriptors

Molecular Weight	402.9
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	5
Exact Mass	402.1359723
Monoisotopic Mass	402.1359723
Topological Polar Surface Area	97.4
Heavy Atom Count	29
Formal Charge	0
Complexity	607

GHS Hazard Classification

Reported hazard statements	H302 (100%), H319 (100%)

Documented Uses

• Breast Feeding; Lactation; Milk, Human; Anti-Infective Agents; Antiviral Agents; Anti-HIV Agents; Anti-Retroviral Agents; Reverse Transcriptase Inhibitors
• Rilpivirine (brand names: Edurant and Edurant PED) is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for use with other HIV medicines for the treatment of HIV in adults and children 2 years of age and older who weigh at least 31 lb (14 kg) who have never taken HIV medicines before and who meet certain requirements, as determined by a health care provider.
• Rilpivirine (brand name: Edurant) is also FDA-approved for use with oral cabotegravir (brand name: Vocabria) for the short-term treatment of HIV in adults and children 12 years of age and older who weigh at least 77 lb (35 kg) and who meet certain requirements, as determined by a health care provider.
• Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs)
• Inhibitors of reverse transcriptase (RNA-DIRECTED DNA POLYMERASE), an enzyme that synthesizes DNA on an RNA template.
• Agents used to treat AIDS and/or stop the spread of the HIV infection. These do not include drugs used to treat symptoms or opportunistic infections associated with AIDS.

Synonyms

Rilpivirine hydrochloride; Rilpivirine HCl; 700361-47-3; Edurant; TMC278 hydrochloride; 212WAX8KDD; EDURANT PED; Rilpivirine (as hydrochloride); TMC-278 HYDROCHLORIDE; CHEBI:68602; DTXSID80220320; EVIPLERA COMPONENT RILPIVIRINE HYDROCHLORIDE; JULUCA COMPONENT RILPIVIRINE HYDROCHLORIDE; RefChem:55981; DTXCID80142811; (E)-4-((4-((4-(2-Cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)amino)benzonitrile hydrochloride

Frequently Asked Questions

What are the CAS number and molecular formula of Rilpivirine hydrochloride?

CAS 700361-47-3; molecular formula C22H19ClN6; molecular weight — g/mol.

What other names is Rilpivirine hydrochloride known by?

Rilpivirine hydrochloride, Rilpivirine HCl, 700361-47-3, Edurant, TMC278 hydrochloride, 212WAX8KDD.

Is Rilpivirine hydrochloride classified as hazardous?

Hazard statements reported: H302, H319.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.