甲氧明

Description

methoxamine · CAS 390-28-3 · C11H17NO3. UNII HUQ1KC1YLI. Solubility: Soluble (185 g/L); Solubility: 9.21e+00 g/L; LogP: 0.8.

Identification

CAS Registry Number	390-28-3
PubChem CID	6082
Molecular formula	C11H17NO3
IUPAC name	2-amino-1-(2,5-dimethoxyphenyl)propan-1-ol
UNII (FDA)	HUQ1KC1YLI

Computed Descriptors

Molecular Weight	211.26
XLogP3	0.5
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	4
Exact Mass	211.12084340
Monoisotopic Mass	211.12084340
Topological Polar Surface Area	64.7
Heavy Atom Count	15
Formal Charge	0

Physical & Chemical Properties

Solubility	Soluble (185 g/L)
Solubility	9.21e+00 g/L
LogP	0.8

Physical description & handling notes

• Solid
• 148.43 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 151.28 Ų [M+K]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 142.14 Ų [M+H-H2O]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

Documented Uses

• Indicated for the treatment and management of hypotension.
• Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
• Drugs used to cause constriction of the blood vessels.
• Compounds that bind to and activate ADRENERGIC ALPHA-1 RECEPTORS.
• C01C - Cardiac stimulants excl. cardiac glycosides
• C01CA - Adrenergic and dopaminergic agents

Synonyms

methoxamine; Methoxamin; 390-28-3; 2-amino-1-(2,5-dimethoxyphenyl)propan-1-ol; Methoxamedrine; Pseudomethoxamine; Metossamina; CHEBI:6839; Benzenemethanol, alpha-(1-aminoethyl)-2,5-dimethoxy-; NRL001; DTXSID0023290; NRL-001; Methoxamedrin; Vasoxin; Wellcome, Metoxamine; RefChem:811759

Frequently Asked Questions

What are the CAS number and molecular formula of methoxamine?

CAS 390-28-3; molecular formula C11H17NO3; molecular weight — g/mol.

What other names is methoxamine known by?

methoxamine, Methoxamin, 390-28-3, 2-amino-1-(2,5-dimethoxyphenyl)propan-1-ol, Methoxamedrine, Pseudomethoxamine.

What are the key physical properties of methoxamine?

Solubility: Soluble (185 g/L); Solubility: 9.21e+00 g/L; LogP: 0.8.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.