洛沙平

Name: 洛沙平
Brand: 济南圣和化工有限公司

CAS 1977-10-2C18H18ClN3OMW 327.8

济南圣和化工有限公司现供应有机化学品——洛沙平（CAS 1977-10-2），分子式 C18H18ClN3O，分子量 327.8。本页理化参数仅供参考，实际常规纯度按批次COA提供(不公开发布)，以批次 COA 及订单确认为准，支持批量采购与长期供货协议。

产品概览

CAS号	1977-10-2
分子式	C18H18ClN3O
分子量	327.8
熔点	109-111 °C
LogP	3.6
纯度	按批次COA提供(不公开发布)
包装	按订单/批次确认(不公开发布)
应用领域	有机化学品
类别	有机化学品

应用领域

有机化学品

洛沙平主要应用于有机化学品。具体使用工况下的添加量与规格要求，欢迎与技术团队沟通确认。

包装与储存

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

运输常规化工运输

样品可协商提供

交期现货/按订单安排

供货能力：洛沙平备有现货，包装形式为按订单/批次确认(不公开发布)。我们支持对公转账并开具增值税发票，山东省内可安排快速配送，省外按物流时效发货，具体请联系 info@591daili.com。

质量与文件

每批产品随货提供 COA（分析证书）；可按需提供 MSDS/技术数据表及第三方检测报告。纯度与包装以批次 COA 及订单确认为准。

关于供应商

济南圣和化工有限公司位于山东济南，主营化工原料供应，精选产品齐全，覆盖有机化学品、无机化学品、食品添加剂、医药中间体等多个大类。我们随货提供 COA 分析证书，一个工作日内回复报价，欢迎国内外采购方长期合作。

常见问题

洛沙平的 CAS 号是多少？

洛沙平的 CAS 号为 1977-10-2。

该产品的纯度和包装规格是什么？

常规纯度规格为按批次COA提供(不公开发布)，包装为按订单/批次确认(不公开发布)，随货提供 COA。

洛沙平有什么用途？

主要应用于有机化学品。

如何购买或获取报价？

请发送邮件至 info@591daili.com 或通过 WhatsApp 联系，注明产品名称、CAS 号与需求数量，一个工作日内回复报价。供应商：济南圣和化工有限公司。

PubChem 公开数据

Description

loxapine · CAS 1977-10-2 · C18H18ClN3O. UNII LER583670J. Melting Point: 109-111 °C; Melting Point: 109-110 °C; Melting Point: 109 - 110 °C.

Identification

CAS Registry Number	1977-10-2
PubChem CID	3964
Molecular formula	C18H18ClN3O
IUPAC name	8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine
UNII (FDA)	LER583670J

Computed Descriptors

Molecular Weight	327.8
XLogP3	3.1
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	1
Exact Mass	327.1138399
Monoisotopic Mass	327.1138399
Topological Polar Surface Area	28.1
Heavy Atom Count	23
Formal Charge	0

Physical & Chemical Properties

Melting Point	109-111 °C
Melting Point	109-110 °C
Melting Point	109 - 110 °C
Solubility	1.03e-01 g/L
LogP	3.6
LogP	3.86
Dissociation Constants	7.48
Dissociation Constants	7.5

Physical description & handling notes

Solid
Pale yellowish crystals from petroleum ether
When heated to decomposition it emits very toxic fumes of /hydrogen chloride/ and nitroxides.
175.7 Å² [M+H]+ [CCS Type: TW; Method: Major Mix IMS/Tof Calibration Kit (Waters)]
178.56 Å² [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
174.44 Å² [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

GHS Hazard Classification

Reported hazard statements	H301 (100%)

H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]

P264, P270, P301+P316, P321, P330, P405, and P501 (click each P-code to see the statement)

Documented Uses

For the management of the manifestations of psychotic disorders such as schizophrenia
Netherlands patent application 6,406,089 corresponds to Schmutz et al, US patent 3,546,226 (1964, 1970 both to Wander); Eidem, Helv Chim Acta 50, 245 (1967); Coppola, US patent 3,412,193 (1968 to American Cyanamid).
Loxapine is a conventional antipsychotic used in the therapy of schizophrenia. Loxapine therapy is commonly associated with minor serum aminotransferase elevations and in very rare instances has been linked to clinically apparent acute liver injury.
Breast Feeding; Lactation; Antipsychotic Agents
Loxapine (Class: Other Substances, Added Date: 07-2000)
Antipsychotic Agents; Dopamine Antagonists

Synonyms

loxapine; 1977-10-2; Cloxazepine; Oxilapine; Loxapin; Adasuve; Loxapina; Loxapinum; Hydrofluoride 3170; CL-62362; SUM 3170; SUM-3170; HF 3170; LW 3170; Dibenz[b,f][1,4]oxazepine, 2-chloro-11-(4-methyl-1-piperazinyl)-; CL 62362

Frequently Asked Questions

What are the CAS number and molecular formula of loxapine?

CAS 1977-10-2; molecular formula C18H18ClN3O; molecular weight — g/mol.

What other names is loxapine known by?

loxapine, 1977-10-2, Cloxazepine, Oxilapine, Loxapin, Adasuve.

Is loxapine classified as hazardous?

Hazard statements reported: H301.

What are the key physical properties of loxapine?

Melting Point: 109-111 °C; Melting Point: 109-110 °C; Melting Point: 109 - 110 °C; Solubility: 1.03e-01 g/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

洛沙平