异氟烷（CAS 26675-46-7）：分子式 C3H2ClF5O、分子量 184.49。
| CAS号 | 26675-46-7 |
|---|---|
| 分子式 | C3H2ClF5O |
| 分子量 | 184.49 |
| 熔点 | 48-48.5 |
| 沸点 | 48.5 |
| LogP | 2.1 |
| 应用领域 | Uses: Used as a special solvent and as an inhalation anesthetic、[Merck Index] A stable、non-explosive inhalation anesthetic、relatively free from significant side effects. [ChemIDplus]、Solvent and dispersant for fluorinated materials、MEDICATION、MEDICATION (VET)、Use (kg) in Switzerland (2009): >750、Use (kg、approx.) in Germany (2009): >10000、Consumption (g per capita) in Switzerland (2009): 0.096、Consumption (g per capita、approx.) in Germany (2009): 0.12、Excretion rate: 1、Calculated removal (%): 91.9、For induction and maintenance of general anesthesia.、Use Classification: Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients、Methods of Manufacturing: Trifluoroethanol is methylated with dimethyl sulfate to form the methyl ether、which is then chlorinated to the dichloromethyl ether ... This latter compound、on treatment with HF、SbCl5 forms the product.、Isoflurane is prepared by chlorination of 2、2、2-trifluoroethoxydifluoromethane、itself obtained by alkylation of trifluoroethanol with difluorochloromethane.、Preparation: Croix、Terrell、DE 1814962 (1969)、US 3535425 (both to Air Reduction)、Formulations、Preparations: FORANE (isoflurane、USP) is also supplied in the、250 mL、aluminum bottles.、FORANE (isoflurane、USP) is packaged in 100 mL and 250 mL amber-colored bottles.、Isoflurane USP is packaged in 250mL (NDC 66794-013-25) and 100mL (NDC 66794-013-10) amber-colored bottles.、Vet |
登记用途：Uses: Used as a special solvent and as an inhalation anesthetic、[Merck Index] A stable、non-explosive inhalation anesthetic、relatively free from significant side effects. [ChemIDplus]、Solvent and dispersant for fluorinated materials、MEDICATION、MEDICATION (VET)、Use (kg) in Switzerland (2009): >750、Use (kg、approx.) in Germany (2009): >10000、Consumption (g per capita) in Switzerland (2009): 0.096、Consumption (g per capita、approx.) in Germany (2009): 0.12、Excretion rate: 1、Calculated removal (%): 91.9、For induction and maintenance of general anesthesia.、Use Classification: Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients、Methods of Manufacturing: Trifluoroethanol is methylated with dimethyl sulfate to form the methyl ether、which is then chlorinated to the dichloromethyl ether ... This latter compound、on treatment with HF、SbCl5 forms the product.、Isoflurane is prepared by chlorination of 2、2、2-trifluoroethoxydifluoromethane、itself obtained by alkylation of trifluoroethanol with difluorochloromethane.、Preparation: Croix、Terrell、DE 1814962 (1969)、US 3535425 (both to Air Reduction)、Formulations、Preparations: FORANE (isoflurane、USP) is also supplied in the、250 mL、aluminum bottles.、FORANE (isoflurane、USP) is packaged in 100 mL and 250 mL amber-colored bottles.、Isoflurane USP is packaged in 250mL (NDC 66794-013-25) and 100mL (NDC 66794-013-10) amber-colored bottles.、Vet。
异氟烷 是一种化工化合物，登记 CAS 号为 26675-46-7，分子式 C3H2ClF5O（分子量 184.49）。
登记 CAS 号：26675-46-7
其分子式 C3H2ClF5O 由 3 个碳、2 个氢、1 个氯、5 个氟、1 个氧 组成。
别名/同义词：异氟烷 · Isoflurane
异氟烷 的 CAS 登记号为 26675-46-7。
分子式 C3H2ClF5O，分子量 184.49。
别名/同义词：异氟烷、Isoflurane。
登记用途：Uses: Used as a special solvent and as an inhalation anesthetic、[Merck Index] A stable、non-explosive inhalation anesthetic、relatively free from significant side effects. [ChemIDplus]、Solvent and dispersant for fluorinated materials、MEDICATION、MEDICATION (VET)、Use (kg) in Switzerland (2009): >750、Use (kg、approx.) in Germany (2009): >10000、Consumption (g per capita) in Switzerland (2009): 0.096、Consumption (g per capita、approx.) in Germany (2009): 0.12、Excretion rate: 1、Calculated removal (%): 91.9、For induction and maintenance of general anesthesia.、Use Classification: Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients、Methods of Manufacturing: Trifluoroethanol is methylated with dimethyl sulfate to form the methyl ether、which is then chlorinated to the dichloromethyl ether ... This latter compound、on treatment with HF、SbCl5 forms the product.、Isoflurane is prepared by chlorination of 2、2、2-trifluoroethoxydifluoromethane、itself obtained by alkylation of trifluoroethanol with difluorochloromethane.、Preparation: Croix、Terrell、DE 1814962 (1969)、US 3535425 (both to Air Reduction)、Formulations、Preparations: FORANE (isoflurane、USP) is also supplied in the、250 mL、aluminum bottles.、FORANE (isoflurane、USP) is packaged in 100 mL and 250 mL amber-colored bottles.、Isoflurane USP is packaged in 250mL (NDC 66794-013-25) and 100mL (NDC 66794-013-10) amber-colored bottles.、Vet。
异氟烷（CAS 26675-46-7）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 26675-46-7 |
|---|---|
| PubChem CID | 3763 |
| Molecular formula | C3H2ClF5O |
| IUPAC name | 2-chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane |
| UNII (FDA) | CYS9AKD70P |
| Molecular Weight | 184.49 |
|---|---|
| XLogP3 | 2.1 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 2 |
| Exact Mass | 183.9714332 |
| Monoisotopic Mass | 183.9714332 |
| Topological Polar Surface Area | 9.2 |
| Heavy Atom Count | 10 |
| Boiling Point | 48.5 |
|---|---|
| Boiling Point | 48.5 °C |
| Boiling Point | 49 °C |
| Boiling Point | 119.3 °F |
| Melting Point | 48-48.5 |
| Solubility | 4470 |
| Solubility | In water, 4.47X10+3 mg/L at 37 °C |
| Solubility | 3.56e+00 g/L |
| Density | 1.45 |
| Vapor Pressure | 330.0 [mmHg] |
isoflurane; 26675-46-7; 1-Chloro-2,2,2-trifluoroethyl difluoromethyl ether; Forane; 2-Chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane; Forene; Aerrane; Isoflurano; Compound 469; IsoFlo; Isofluranum; Ethane, 2-chloro-2-(difluoromethoxy)-1,1,1-trifluoro-; Terrell; DTXSID3020752; CYS9AKD70P; COMPOUND-469
| GHS notification summary | 2.9% (3 / 103) |
|---|
| GHS notification summary | 2.9% (3 / 103) |
|---|---|
| Reported hazard statements | H336 (93.2%), H373 (40.8%) |
This chemical does not meet GHS hazard criteria for 2.9% (3 of 103) of reports.
H336 (93.2%): May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]
Isoflurane · CAS 26675-46-7 · C3H2ClF5O. UNII CYS9AKD70P. Boiling Point: 48.5; Boiling Point: 48.5 °C; Boiling Point: 49 °C.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Isoflurane