Isopropylantipyrine

Description

Isopropylantipyrine · CAS 479-92-5 · C14H18N2O. UNII OED8FV75PY. LogP: 1.94; Ionization Efficiency: 3.36; Ionization Efficiency: 2.7.

Identification

CAS Registry Number	479-92-5
PubChem CID	3778
Molecular formula	C14H18N2O
IUPAC name	1,5-dimethyl-2-phenyl-4-propan-2-ylpyrazol-3-one
UNII (FDA)	OED8FV75PY

Computed Descriptors

Molecular Weight	230.31
XLogP3	1.7
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	2
Exact Mass	230.141913202
Monoisotopic Mass	230.141913202
Topological Polar Surface Area	23.6
Heavy Atom Count	17
Formal Charge	0

Physical & Chemical Properties

LogP	1.94
Ionization Efficiency	3.36
Ionization Efficiency	2.7
Ionization Efficiency	MeCN (80%)

Physical description & handling notes

• Positive
• Agilent XCT
• Electrospray ionization
• formic acid (5.3nM)
• DOI:
• 150 Ų [M+H]+ [CCS Type: TW]

GHS Hazard Classification

Reported hazard statements	H302 (100%)

Documented Uses

• Use (kg; approx.) in Germany (2009): >1000
• Consumption (g per capita; approx.) in Germany (2009): 0.0122
• 3H-Pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl-: INACTIVE
• Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
• N02B - Other analgesics and antipyretics
• QN02B - Other analgesics and antipyretics

Synonyms

Propyphenazone; 479-92-5; isopropylantipyrine; 4-Isopropylantipyrine; Isopropylphenazone; Propifenazona; Yoshipyrin; Propifenazone; Propyphenazonum; 1-Phenyl-2,3-dimethyl-4-isopropyl-3-pyrazolin-5-one; 1-Phenyl-2,3-dimethyl-4-isopropylpyrazol-5-one; DTXSID6023529; 4-Isopropyl-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one; OED8FV75PY; 3H-Pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl-; CHEBI:135538

Frequently Asked Questions

What are the CAS number and molecular formula of Isopropylantipyrine?

CAS 479-92-5; molecular formula C14H18N2O; molecular weight — g/mol.

What other names is Isopropylantipyrine known by?

Propyphenazone, 479-92-5, isopropylantipyrine, 4-Isopropylantipyrine, Isopropylphenazone, Propifenazona.

Is Isopropylantipyrine classified as hazardous?

Hazard statements reported: H302.

What are the key physical properties of Isopropylantipyrine?

LogP: 1.94; Ionization Efficiency: 3.36; Ionization Efficiency: 2.7; Ionization Efficiency: MeCN (80%).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.