吉特替尼

Name: 吉特替尼
Brand: 济南圣和化工有限公司

CAS 1254053-43-4C29H44N8O3MW 552.7

本页收录吉特替尼，CAS 登记号为 1254053-43-4，分子式 C29H44N8O3，分子量 552.7，归类于有机化学品。作为主营产品之一，济南圣和化工有限公司可提供从公斤级到吨级的稳定供货，随货附 COA 与质检资料。

产品概览

CAS号	1254053-43-4
分子式	C29H44N8O3
分子量	552.7
沸点	696
LogP	4.35
纯度	按批次COA提供(不公开发布)
包装	按订单/批次确认(不公开发布)
应用领域	有机化学品
类别	有机化学品

应用领域

有机化学品

吉特替尼主要应用于有机化学品。具体使用工况下的添加量与规格要求，欢迎与技术团队沟通确认。

包装与储存

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

运输常规化工运输

样品可协商提供

交期现货/按订单安排

供货能力：吉特替尼备有现货，包装形式为按订单/批次确认(不公开发布)。我们支持对公转账并开具增值税发票，山东省内可安排快速配送，省外按物流时效发货，具体请联系 info@591daili.com。

质量与文件

每批产品随货提供 COA（分析证书）；可按需提供 MSDS/技术数据表及第三方检测报告。纯度与包装以批次 COA 及订单确认为准。

关于供应商

选择济南圣和化工有限公司的理由：产品信息透明（含 CAS、分子式、理化参数）、报价响应快（一个工作日内）、单证齐全（COA/MSS/质检资料按需提供）、支持批量与长期协议供货。如需吉特替尼以外的配套原料，也欢迎一并列出需求清单。

常见问题

吉特替尼的 CAS 号是多少？

吉特替尼的 CAS 号为 1254053-43-4。

该产品的纯度和包装规格是什么？

常规纯度规格为按批次COA提供(不公开发布)，包装为按订单/批次确认(不公开发布)，随货提供 COA。

吉特替尼有什么用途？

主要应用于有机化学品。

如何购买或获取报价？

请发送邮件至 info@591daili.com 或通过 WhatsApp 联系，注明产品名称、CAS 号与需求数量，一个工作日内回复报价。供应商：济南圣和化工有限公司。

PubChem 公开数据

Description

Gilteritinib · CAS 1254053-43-4 · C29H44N8O3. UNII 66D92MGC8M. Boiling Point: 696; Solubility: <1 mg/mL; LogP: 4.35.

Identification

CAS Registry Number	1254053-43-4
PubChem CID	49803313
Molecular formula	C29H44N8O3
IUPAC name	6-ethyl-3-[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]anilino]-5-(oxan-4-ylamino)pyrazine-2-carboxamide
UNII (FDA)	66D92MGC8M

Computed Descriptors

Molecular Weight	552.7
XLogP3	3.5
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	9
Exact Mass	552.35363730
Monoisotopic Mass	552.35363730
Topological Polar Surface Area	121
Heavy Atom Count	40
Formal Charge	0

Physical & Chemical Properties

Boiling Point	696
Solubility	<1 mg/mL
LogP	4.35

GHS Hazard Classification

Reported hazard statements	H360 (100%), H373 (100%)

H360 (100%): May damage fertility or the unborn child [Danger Reproductive toxicity]

H373 (100%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]

Documented Uses

Gilteritinib is an orally available small molecule inhibitor of FMS-like tyrosine kinase 3 (FLT3) which is used as an antineoplastic agent in the treatment of acute myeloid leukemia with FLT3 mutations. Gilteritinib is associated with a moderate rate of serum aminotransferase elevations during therapy and is suspected to cause rare instances of clinically apparent acute liver injury.
Breast Feeding; Lactation; Milk, Human; Antineoplastic Agents; Enzyme Inhibitors; Protein Kinase Inhibitors; Signal Transduction Inhibitors; Tyrosine Kinase Inhibitors
Avoid grapefruit products. Grapefruit inhibits CYP3A metabolism, which may increase the serum concentration of gilteritinib.
Avoid St. John's Wort. This herb induces CYP3A4 and p-glycoprotein, which may reduce the serum concentration of gilteritinib.
Take at the same time every day.
Protein kinase inhibitors that inhibit TYROSINE PROTEIN KINASES.

Synonyms

Gilteritinib; 1254053-43-4; ASP2215; ASP-2215; gilteritinibum; ASP 2215; 66D92MGC8M; CHEBI:145372; DTXSID701027949; RefChem:58108; L01XE54; DTXCID601513517; MFCD28144685; Gilteritinib HCl; Gilteritinib [USAN:INN]; UNII-66D92MGC8M

Frequently Asked Questions

What are the CAS number and molecular formula of Gilteritinib?

CAS 1254053-43-4; molecular formula C29H44N8O3; molecular weight — g/mol.

What other names is Gilteritinib known by?

Gilteritinib, 1254053-43-4, ASP2215, ASP-2215, gilteritinibum, ASP 2215.

Is Gilteritinib classified as hazardous?

Hazard statements reported: H360, H373.

What are the key physical properties of Gilteritinib?

Boiling Point: 696; Solubility: <1 mg/mL; LogP: 4.35.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.