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GSK1120212 (DMSO solvate)

CAS 1187431-43-1C28H29FIN5O5SMW 693.5

GSK1120212 (DMSO solvate) (CAS No. 1187431-43-1) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Organic Chemicals. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Product Overview

CAS Number1187431-43-1
Molecular FormulaC28H29FIN5O5S
Molecular Weight693.5
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsOrganic Chemicals
CategoryOrganic Chemicals

Applications

Organic Chemicals

Packaging & Storage

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
ShippingStandard chemical transport
SampleAvailable on request
Lead TimeIn stock / per order

Quality & Documentation

COA (Certificate of Analysis) is provided with every batch. MSDS/technical data sheets and third-party test reports are available on request. Purity and packaging are subject to batch COA and order confirmation.

Frequently Asked Questions

What is the CAS number of GSK1120212 (DMSO solvate)?

The CAS number of GSK1120212 (DMSO solvate) is 1187431-43-1.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of GSK1120212 (DMSO solvate)?

Main applications include Organic Chemicals.

How do I buy GSK1120212 (DMSO solvate) or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

GSK1120212 (DMSO solvate) · CAS 1187431-43-1 · C28H29FIN5O5S. UNII BSB9VJ5TUT.

Identification

CAS Registry Number1187431-43-1
PubChem CID50992434
Molecular formulaC28H29FIN5O5S
IUPAC nameN-[3-[3-cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide;methylsulfinylmethane
UNII (FDA)BSB9VJ5TUT

Computed Descriptors

Molecular Weight693.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count5
Exact Mass693.09182
Monoisotopic Mass693.09182
Topological Polar Surface Area138
Heavy Atom Count41
Formal Charge0
Complexity1120

GHS Hazard Classification

Reported hazard statementsH317 (100%), H361 (66.7%), H372 (100%), H400 (33.3%), H410 (100%)

H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]

H361 (66.7%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

Documented Uses

  • Mekinist (Trametinib Dimethyl Sulfoxide)
  • Trametinib dimethyl sulfoxide is approved to be used alone or with dabrafenib mesylate to treat patients whose cancer has a certain mutation in the BRAF gene, including:
  • • Anaplastic thyroid cancer that has spread and cannot be treated with local therapy. It is used with dabrafenib mesylate.
  • • Glioma that is low grade in children aged 1 year and older who require systemic therapy. It is used with dabrafenib mesylate.
  • • With dabrafenib mesylate in patients who have had surgery to remove cancer that has spread to the lymph nodes.
  • • Alone or with dabrafenib mesylate in patients whose cancer cannot be removed by surgery or has spread to other parts of the body.

Synonyms

TRAMETINIB DIMETHYL SULFOXIDE; Trametinib DMSO; GSK1120212B; Mekinst; UNII-BSB9VJ5TUT; BSB9VJ5TUT; GSK-1120212B; CHEBI:75991; DTXSID30152223; RefChem:57976; DTXCID0074714; 1187431-43-1; Trametinib DMSO solvate; Trametinib (DMSO solvate); MFCD21609250; Trametinib dimethyl sulfoxide [USAN]

Frequently Asked Questions

What are the CAS number and molecular formula of GSK1120212 (DMSO solvate)?

CAS 1187431-43-1; molecular formula C28H29FIN5O5S; molecular weight — g/mol.

What other names is GSK1120212 (DMSO solvate) known by?

TRAMETINIB DIMETHYL SULFOXIDE, Trametinib DMSO, GSK1120212B, Mekinst, UNII-BSB9VJ5TUT, BSB9VJ5TUT.

Is GSK1120212 (DMSO solvate) classified as hazardous?

Hazard statements reported: H317, H361, H372, H400, H410.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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Supplier: Jinan Shenghe Chemical Co., Ltd.

中文页面: GSK1120212(DMSO 溶剂化物)

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