更昔洛韦钠

Description

Ganciclovir sodium · CAS 107910-75-8 · C9H12N5NaO4. UNII 02L083W284.

Identification

CAS Registry Number	107910-75-8
PubChem CID	23700083
Molecular formula	C9H12N5NaO4
IUPAC name	sodium 2-amino-9-(1,3-dihydroxypropan-2-yloxymethyl)purin-6-olate
UNII (FDA)	02L083W284

Computed Descriptors

Molecular Weight	277.21
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	5
Exact Mass	277.07869816
Monoisotopic Mass	277.07869816
Topological Polar Surface Area	142
Heavy Atom Count	19
Formal Charge	0
Complexity	273

GHS Hazard Classification

Reported hazard statements	H350 (100%), H360 (100%)

Documented Uses

• Ganciclovir (injection) is an antiviral prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of cytomegalovirus retinitis (CMV retinitis) in adults who are immunocompromised, including individuals with AIDS. Ganciclovir (injection) is also FDA-approved for the prevention of CMV disease in recipients of organ transplants who are at risk for CMV diseases.
• CMV diseases, including CMV retinitis, can be opportunistic infections (OIs) of HIV.
• Antiviral (Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor)
• Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.
• Nucleoside Analog Antiviral [EPC]; Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor [EPC]; Nucleoside Analog [EXT]; DNA Polymerase Inhibitors [MoA]

Synonyms

GANCICLOVIR SODIUM; 107910-75-8; Ganciclovir Sodium Salt; Cytovene IV; Cytovene-IV; RS-21592 sodium; Ganciclovir (as sodium); DTXSID20883175; DHPG Sodium; GCV Sodium; 02L083W284; 9-((2-Hydroxy-1-(hydroxymethyl)ethoxy)methyl)guanine, monosodium salt; denosine; RefChem:56510; DTXCID201022732; BW-759

Frequently Asked Questions

What are the CAS number and molecular formula of Ganciclovir sodium?

CAS 107910-75-8; molecular formula C9H12N5NaO4; molecular weight — g/mol.

What other names is Ganciclovir sodium known by?

GANCICLOVIR SODIUM, 107910-75-8, Ganciclovir Sodium Salt, Cytovene IV, Cytovene-IV, RS-21592 sodium.

Is Ganciclovir sodium classified as hazardous?

Hazard statements reported: H350, H360.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.