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Filgotinib

CAS 1206161-97-8C21H23N5O3SMW 425.5

Filgotinib (CAS No. 1206161-97-8) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Organic Chemicals. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Product Overview

CAS Number1206161-97-8
Molecular FormulaC21H23N5O3S
Molecular Weight425.5
LogP1.4
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsOrganic Chemicals
CategoryOrganic Chemicals

Applications

Organic Chemicals

Packaging & Storage

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
ShippingStandard chemical transport
SampleAvailable on request
Lead TimeIn stock / per order

Quality & Documentation

COA (Certificate of Analysis) is provided with every batch. MSDS/technical data sheets and third-party test reports are available on request. Purity and packaging are subject to batch COA and order confirmation.

Frequently Asked Questions

What is the CAS number of Filgotinib?

The CAS number of Filgotinib is 1206161-97-8.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Filgotinib?

Main applications include Organic Chemicals.

How do I buy Filgotinib or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Filgotinib · CAS 1206161-97-8 · C21H23N5O3S. UNII 3XVL385Q0M.

Identification

CAS Registry Number1206161-97-8
PubChem CID49831257
Molecular formulaC21H23N5O3S
IUPAC nameN-[5-[4-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide
UNII (FDA)3XVL385Q0M

Computed Descriptors

Molecular Weight425.5
XLogP31.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Exact Mass425.15216079
Monoisotopic Mass425.15216079
Topological Polar Surface Area105
Heavy Atom Count30
Formal Charge0

Physical description & handling notes

  • In addition to targeted Janus kinase (JAK) 1 inhibition, filgotinib targets pro-inflammatory cytokine signalling by inhibiting IL-6 induced STAT1 phosphorylation. Serum C-reactive protein levels are also reduced in response to filgotinib administration.

GHS Hazard Classification

Reported hazard statementsH315 (100%), H319 (100%), H335 (100%)

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

Documented Uses

  • Breast Feeding; Lactation; Milk, Human; Enzyme Inhibitors; Protein Kinase Inhibitors; Signal Transduction Inhibitors; Janus Kinase Inhibitors; JAK Inhibitors
  • L - Antineoplastic and immunomodulating agents
  • L04AF - Janus-associated kinase (jak) inhibitors
  • QL - Antineoplastic and immunomodulating agents
  • QL04AF - Janus-associated kinase (jak) inhibitors
  • Of the total administered dose of filgotinib, approximately 87% undergoes renal elimination while 15% undergoes faecal elimination.

Synonyms

Filgotinib; 1206161-97-8; GLPG-0634; 3XVL385Q0M; GS-6034 FREE BASE; GLPG 0634; G146034; G-146034; DTXSID80152935; filgotinibum; RefChem:921607; DTXCID7075426; 1206101-20-3; GLPG0634; Filgotinib (GLPG0634); N-(5-(4-((1,1-dioxidothiomorpholino)methyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide

Frequently Asked Questions

What are the CAS number and molecular formula of Filgotinib?

CAS 1206161-97-8; molecular formula C21H23N5O3S; molecular weight — g/mol.

What other names is Filgotinib known by?

Filgotinib, 1206161-97-8, GLPG-0634, 3XVL385Q0M, GS-6034 FREE BASE, GLPG 0634.

Is Filgotinib classified as hazardous?

Hazard statements reported: H315, H319, H335.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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Supplier: Jinan Shenghe Chemical Co., Ltd.

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