甲硫咪唑

Description

2-Mercapto-1-methylimidazole · CAS 60-56-0 · C4H6N2S. UNII 554Z48XN5E. Melting Point: 143-146 °C; Melting Point: 146-148 °C; Melting Point: 146 °C.

Identification

CAS Registry Number	60-56-0
PubChem CID	1349907
Molecular formula	C4H6N2S
IUPAC name	3-methyl-1H-imidazole-2-thione
UNII (FDA)	554Z48XN5E

Computed Descriptors

Molecular Weight	114.17
XLogP3	-0.3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	0
Exact Mass	114.02516937
Monoisotopic Mass	114.02516937
Topological Polar Surface Area	47.4
Heavy Atom Count	7
Formal Charge	0

Physical & Chemical Properties

Melting Point	143-146 °C
Melting Point	146-148 °C
Melting Point	146 °C
Solubility	1.13e+01 g/L
LogP	log Kow = -0.34
LogP	-0.2
LogP	-0.22

Physical description & handling notes

• Solid
• LEAFLETS FROM ALCOHOL
• WHITE TO PALE BUFF, CRYSTALLINE SUBSTANCE; STARCH-LIKE IN APPEARANCE & TO TOUCH
• FAINT, CHARACTERISTIC
• 280 °C WITH SOME DECOMP
• Freely soluble

Regulatory Status

GHS notification summary	1.8% (1 / 57)

GHS Hazard Classification

GHS notification summary	1.8% (1 / 57)
Reported hazard statements	H302 (17.5%), H317 (84.2%), H361 (80.7%)

Documented Uses

• In cyanide-free silver electroplating. THERAP CAT: Antihyperthyroid.
• Use (kg; approx.) in Germany (2009): >250
• Consumption (g per capita; approx.) in Germany (2009): 0.00305
• Consumption (g per capita) in the USA (2002): 0.00251
• Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
• PREPD BY TREATING AMINOACETALDEHYDE DIETHYL ACETAL WITH METHYL ISOTHIOCYANATE; FROM THIOCYANIC ACID & N-SUBSTITUTED AMINO ACETALS.

Synonyms

methimazole; 60-56-0; thiamazole; Tapazole; 1-Methyl-1H-imidazole-2-thiol; Methimazol; 1-Methylimidazole-2-thiol; Mercazolyl; Thiamazol; Mercazole; Thymidazol; Thymidazole; Favistan; Mercaptazole; Metothyrine; Metazolo

Frequently Asked Questions

What are the CAS number and molecular formula of 2-Mercapto-1-methylimidazole?

CAS 60-56-0; molecular formula C4H6N2S; molecular weight — g/mol.

What other names is 2-Mercapto-1-methylimidazole known by?

methimazole, 60-56-0, thiamazole, Tapazole, 1-Methyl-1H-imidazole-2-thiol, Methimazol.

Is 2-Mercapto-1-methylimidazole classified as hazardous?

1.8% of GHS notifications report no hazard classification (1 of 57).

What are the key physical properties of 2-Mercapto-1-methylimidazole?

Melting Point: 143-146 °C; Melting Point: 146-148 °C; Melting Point: 146 °C; Solubility: 1.13e+01 g/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.