12-羟基硬脂酸

Description

12-Hydroxystearic Acid · CAS 106-14-9 · C18H36O3. UNII 933ANU3H2S. Melting Point: 82 °C.

Identification

CAS Registry Number	106-14-9
PubChem CID	7789
Molecular formula	C18H36O3
IUPAC name	12-hydroxyoctadecanoic acid
UNII (FDA)	933ANU3H2S

Computed Descriptors

Molecular Weight	300.5
XLogP3	6.5
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	16
Exact Mass	300.26644501
Monoisotopic Mass	300.26644501
Topological Polar Surface Area	57.5
Heavy Atom Count	21
Formal Charge	0

Physical & Chemical Properties

Melting Point	82 °C

Physical description & handling notes

• Dry Powder; Other Solid; Large Crystals; Liquid
• Solid; [HSDB] White powder; [MSDSonline]
• Crystals from alcohol
• Soluble in alcohol, ether, chloroform; insoluble in water
• 179.1 Ų [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Calculation: Single Field; Dataset: Oxylipins]
• 178.9 Ų [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: TOXCAST; Source Identifier: DTXSID8026725]

Regulatory Status

Regulatory & Food Contact	FDA Cumulative Estimated Daily Intake (CEDI): FCS FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS CIR / INCI: Cosmetic ingredients (Hydroxystearic Acid) -> CIR (Cosmetic Ingredient Review) CIR / INCI: Emulsifying; Cleansing; Surfactant
GHS notification summary	60.2% (305 / 507)

GHS Hazard Classification

GHS notification summary	60.2% (305 / 507)
Reported hazard statements	H315 (17.4%), H319 (17.4%), H335 (17.2%), H400 (22.5%)

Documented Uses

• CIR ingredient: Hydroxystearic Acid
• Used in lithium greases; as a chemical intermediate; as a defoamer in foods; as an ingredient in cosmetics; [HSDB]
• Hydroxystearic acid is used as a surfactant-cleansing agent in cosmetic products.
• 12-Hydroxystearic acid has been used as a textile lubricant and as a saponifiable base for greases. 12-Hydroxystearic acid-polyethylene glycol block polymers have been approved by FDA for use as surfactants, for dispersions of polyacrylamide retention and draining aids, employed prior to the sheet forming operation in the manufacture of paper and paperboard that come in contact with aqueous and fatty foods.
• Lithium greases; chemical intermediates
• Used for skin and hair-cleaning purposes and as emulsifiers in cosmetics.

Synonyms

12-Hydroxystearic acid; 12-HYDROXYOCTADECANOIC ACID; 106-14-9; DL-12-Hydroxystearic acid; Cerit Fac 3; Hydrofol acid 200; Ceroxin GL; Barolub FTO; Stearic acid, 12-hydroxy-; Loxiol G 21; NSC 2385; 12-hydroxy-octadecanoic acid; DTXSID8026725; HSDB 5368; EINECS 203-366-1; EINECS 253-004-1

Frequently Asked Questions

What are the CAS number and molecular formula of 12-Hydroxystearic Acid?

CAS 106-14-9; molecular formula C18H36O3; molecular weight — g/mol.

What other names is 12-Hydroxystearic Acid known by?

12-Hydroxystearic acid, 12-HYDROXYOCTADECANOIC ACID, 106-14-9, DL-12-Hydroxystearic acid, Cerit Fac 3, Hydrofol acid 200.

What is the regulatory status of 12-Hydroxystearic Acid?

Documented regulatory listings: FDA Cumulative Estimated Daily Intake (CEDI): FCS; FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS; CIR / INCI: Cosmetic ingredients (Hydroxystearic Acid) -> CIR (Cosmetic Ingredient Review).

Is 12-Hydroxystearic Acid classified as hazardous?

60.2% of GHS notifications report no hazard classification (305 of 507).

What are the key physical properties of 12-Hydroxystearic Acid?

Melting Point: 82 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.