二甲基甲酰胺 (DMF)

Description

Dimethyl Formamide (DMF) · CAS 68-12-2 · C3H7NO. UNII 8696NH0Y2X. Boiling Point: 300 to 313 °F at 760 mmHg (NTP, 1992); Boiling Point: 153; Boiling Point: 152.8 °C.

Identification

CAS Registry Number	68-12-2
PubChem CID	6228
Molecular formula	C3H7NO
IUPAC name	N,N-dimethylformamide
UNII (FDA)	8696NH0Y2X

Computed Descriptors

Molecular Weight	73.09
XLogP3	-1
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	0
Exact Mass	73.052763847
Monoisotopic Mass	73.052763847
Topological Polar Surface Area	20.3
Heavy Atom Count	5
Formal Charge	0

Physical & Chemical Properties

Boiling Point	300 to 313 °F at 760 mmHg (NTP, 1992)
Boiling Point	153
Boiling Point	152.8 °C
Boiling Point	BP: 76 °C at 39 mm Hg; 25 °C at 3.7 mm Hg
Boiling Point	153 °C
Boiling Point	307 °F
Boiling Point	153 °C @760 [mm Hg]
Melting Point	-78 °F (NTP, 1992)
Melting Point	-60.4
Melting Point	-60.3 °C

Physical description & handling notes

• N,n-dimethylformamide appears as a water-white liquid with a faint fishy odor. Flash point 136 °F. Slightly less dense than water. Vapors heavier than air. Toxic by inhalation or skin absorption. May irritate eyes.
• Liquid; CBI
• Colorless to pale-yellow liquid with a faint, amine-like odor; [NIOSH]
• Liquid
• COLOURLESS-TO-YELLOW LIQUID WITH CHARACTERISTIC ODOUR.
• Colorless to pale-yellow liquid with a faint, amine-like odor.

Regulatory Status

Regulatory & Food Contact	FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS
GHS notification summary	0.1% (1 / 1434)

GHS Hazard Classification

GHS notification summary	0.1% (1 / 1434)
Reported hazard statements	H312, H319, H332, H226 (33.5%), H360 (93.5%), H315, H331, H350

Documented Uses

• Dimethylformamide is primarily used as an industrial solvent. Dimethylformamide solutions are used to process polymer fibers, films, and surface coatings; to permit easy spinning of acrylic fibers; to produce wire enamels, and as a crystallization medium in the pharmaceutical industry.
• Used as a solvent in acrylic fiber spinning, textile dyeing, and paint stripping; also used in coating, printing, gluing, and pharmaceutical manufacturing; [ Used as a solvent for vinyl resins; [Kanerva, p. 1786] Used in synthetic leather manufacturing; [JOEM 2004;46:729-736]
• Semiconductor Manufacturing [Category: Industry]
• Textiles (Fiber & Fabric Manufacturing) [Category: Industry]
• Painting (Solvents) [Category: Paint]
• Working with Glues and Adhesives [Category: Other]

Synonyms

N,N-DIMETHYLFORMAMIDE; Dimethylformamide; 68-12-2; Dimethyl formamide; N-Formyldimethylamine; Formamide, N,N-dimethyl-; Dimethylformamid; DMFA; N,N-Dimethyl formamide; Formyldimethylamine; Dimetilformamide; Dwumetyloformamid; Dimetylformamidu; DMF (amide); NCI-C60913; DTXSID6020515

Frequently Asked Questions

What are the CAS number and molecular formula of Dimethyl Formamide (DMF)?

CAS 68-12-2; molecular formula C3H7NO; molecular weight — g/mol.

What other names is Dimethyl Formamide (DMF) known by?

N,N-DIMETHYLFORMAMIDE, Dimethylformamide, 68-12-2, Dimethyl formamide, N-Formyldimethylamine, Formamide, N,N-dimethyl-.

What is the regulatory status of Dimethyl Formamide (DMF)?

Documented regulatory listings: FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS.

Is Dimethyl Formamide (DMF) classified as hazardous?

0.1% of GHS notifications report no hazard classification (1 of 1434).

What are the key physical properties of Dimethyl Formamide (DMF)?

Boiling Point: 300 to 313 °F at 760 mmHg (NTP, 1992); Boiling Point: 153; Boiling Point: 152.8 °C; Boiling Point: BP: 76 °C at 39 mm Hg; 25 °C at 3.7 mm Hg.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.