胡莫柳酯

Description

Homosalate · CAS 118-56-9 · C16H22O3. UNII V06SV4M95S. Boiling Point: 322 to 329 °F at 760 mmHg (NTP, 1992).

Identification

CAS Registry Number	118-56-9
PubChem CID	8362
Molecular formula	C16H22O3
IUPAC name	(3,3,5-trimethylcyclohexyl) 2-hydroxybenzoate
UNII (FDA)	V06SV4M95S

Computed Descriptors

Molecular Weight	262.34
XLogP3	5
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	3
Exact Mass	262.15689456
Monoisotopic Mass	262.15689456
Topological Polar Surface Area	46.5
Heavy Atom Count	19
Formal Charge	0

Physical & Chemical Properties

Boiling Point	322 to 329 °F at 760 mmHg (NTP, 1992)

Physical description & handling notes

• 3,3,5-trimethylcyclohexylsalicylate appears as viscous or light yellow to slightly tan liquid or oil. (NTP, 1992)
• greater than 200 °F (NTP, 1992)
• Insoluble (<1 mg/ml at 79 °F) (NTP, 1992)
• 1.045 at 77 °F (NTP, 1992) - Denser than water; will sink
• 156.63 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 157.77 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

Regulatory Status

Regulatory & Food Contact	CIR / INCI: Uv absorber; Uv filter; Skin conditioning
GHS notification summary	67% (152 / 227)

GHS Hazard Classification

GHS notification summary	67% (152 / 227)
Reported hazard statements	H315 (16.7%), H319 (16.7%), H335 (16.7%), H410 (11.5%)

Documented Uses

• Cosmetics -> Uv absorber; Uv filter; Skin conditioning
• Not Known or Reasonably Ascertainable
• Information on 52 consumer products that contain Homosalate in the following categories is provided:
• All Other Chemical Product and Preparation Manufacturing
• Benzoic acid, 2-hydroxy-, 3,3,5-trimethylcyclohexyl ester: ACTIVE
• As ingredient in many sunscreen for protection against sunburn, skin aging and skin cancer.

Synonyms

Homosalate; 118-56-9; Homomenthyl salicylate; Heliophan; 3,3,5-Trimethylcyclohexyl 2-hydroxybenzoate; Homosalato; (3,3,5-trimethylcyclohexyl) 2-hydroxybenzoate; Homosalatum; Benzoic acid, 2-hydroxy-, 3,3,5-trimethylcyclohexyl ester; Salicylic Acid 3,3,5-Trimethylcyclohexyl Ester; NSC-164918; V06SV4M95S; Sunscreen SKINCARE; BULUBIU ADVANCED; RefChem:55307; dAlba Vegan Fresh Sun Stick

Frequently Asked Questions

What are the CAS number and molecular formula of Homosalate?

CAS 118-56-9; molecular formula C16H22O3; molecular weight — g/mol.

What other names is Homosalate known by?

Homosalate, 118-56-9, Homomenthyl salicylate, Heliophan, 3,3,5-Trimethylcyclohexyl 2-hydroxybenzoate, Homosalato.

What is the regulatory status of Homosalate?

Documented regulatory listings: CIR / INCI: Uv absorber; Uv filter; Skin conditioning.

Is Homosalate classified as hazardous?

67% of GHS notifications report no hazard classification (152 of 227).

What are the key physical properties of Homosalate?

Boiling Point: 322 to 329 °F at 760 mmHg (NTP, 1992).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.