三辛酸甘油酯

Description

Tricaprylin · CAS 538-23-8 · C27H50O6. UNII 6P92858988. Boiling Point: 451.6 °F at 760 mmHg (NTP, 1992); Boiling Point: 233 °C; Boiling Point: 232.00 to 234.00 °C. @ 760.00 mm Hg.

Identification

CAS Registry Number	538-23-8
PubChem CID	10850
Molecular formula	C27H50O6
IUPAC name	2,3-di(octanoyloxy)propyl octanoate
UNII (FDA)	6P92858988

Computed Descriptors

Molecular Weight	470.7
XLogP3	8.9
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	26
Exact Mass	470.36073931
Monoisotopic Mass	470.36073931
Topological Polar Surface Area	78.9
Heavy Atom Count	33
Formal Charge	0

Physical & Chemical Properties

Boiling Point	451.6 °F at 760 mmHg (NTP, 1992)
Boiling Point	233 °C
Boiling Point	232.00 to 234.00 °C. @ 760.00 mm Hg
Melting Point	50 °F (NTP, 1992)
Melting Point	10 °C
Melting Point	9.00 to 11.00 °C. @ 760.00 mm Hg
Flash Point	351 °F (NTP, 1992)
Solubility	0.4 mg/L @ 37 °C (exp)
Density	0.9540 at 20 °C
Vapor Pressure	0.06 [mmHg]

Physical description & handling notes

• Tricaprylin is an odorless viscous clear colorless to amber-brown liquid. (NTP, 1992)
• Colorless to amber-brown viscous, odorless liquid; mp = 10 deg C; [NTP] Colorless to light yellow odorless liquid; [Acros Organics MSDS]
• Solid
• Clear, colorless to amber liquid
• less than 1 mg/mL at 72 °F (NTP, 1992)
• Miscible in ethanol; very soluble in ether, benzene, chloroform, ligroin

Regulatory Status

Regulatory & Food Contact	CIR / INCI: Cosmetic ingredients (Tricaprylin) -> CIR (Cosmetic Ingredient Review) CIR / INCI: Personal care product -> emollient CIR / INCI: Solvent; Emollient; Skin conditioning
GHS notification summary	99.6% (258 / 259)

GHS Hazard Classification

GHS notification summary	99.6% (258 / 259)

Documented Uses

• 13C-labeled form is used in breath tests for diagnosis of fat malabsorption; [ChemIDplus] Used to make drug suspensions (unstable in aqueous media) and as a solubilizer for flavors, fragrances, and medicinals; [NTP] Used as an energy source for burn patients and those with difficulty digesting long-chain fatty acids, as a skin conditioning agent, and antihistamine; [HSDB]
• Tricaprylin has been used as an energy source for burn patients and for patients having difficulty digesting long-chain fatty acids.
• Skin conditioning agent- occlusive and/or viscosity-increasing agent /in cosmetics/.
• Used as an antihistamine; addicts have added it to paregoric to make "blue velvet," which can cause euphoria by injection.
• Cosmetics -> Solvent; Emollient; Skin conditioning
• Information on 7 consumer products that contain Tricaprylin in the following categories is provided:

Synonyms

Tricaprylin; Trioctanoin; 538-23-8; Tricaprilin; Rato; Glycerol tricaprylate; Glycerol trioctanoate; Caprylin; Trioctanoylglycerol; Glyceryl trioctanoate; Maceight; Caprylic acid triglyceride; Glyceryl tricaprylate; Tricaprylic glyceride; Caprylic triglyceride; Octanoin, tri-

Frequently Asked Questions

What are the CAS number and molecular formula of Tricaprylin?

CAS 538-23-8; molecular formula C27H50O6; molecular weight — g/mol.

What other names is Tricaprylin known by?

Tricaprylin, Trioctanoin, 538-23-8, Tricaprilin, Rato, Glycerol tricaprylate.

What is the regulatory status of Tricaprylin?

Documented regulatory listings: CIR / INCI: Cosmetic ingredients (Tricaprylin) -> CIR (Cosmetic Ingredient Review); CIR / INCI: Personal care product -> emollient; CIR / INCI: Solvent; Emollient; Skin conditioning.

Is Tricaprylin classified as hazardous?

99.6% of GHS notifications report no hazard classification (258 of 259).

What are the key physical properties of Tricaprylin?

Boiling Point: 451.6 °F at 760 mmHg (NTP, 1992); Boiling Point: 233 °C; Boiling Point: 232.00 to 234.00 °C. @ 760.00 mm Hg; Melting Point: 50 °F (NTP, 1992).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.