乙基香兰素 FCC（CAS 121-32-4）：分子式 C9H10O3、分子量 166.17。
| CAS号 | 121-32-4 |
|---|---|
| 分子式 | C9H10O3 |
| 分子量 | 166.17 |
| 熔点 | 171 to 172 °F (NTP, 1992) |
| 沸点 | 285 °C |
| LogP | 1.6 |
| 应用领域 | Uses: Used in perfumes、and organic synthesis、[HSDB]、In flavoring and perfumery、Used as a chemical intermediate、to replace or fortify vanillin.、Reported uses (ppm):、Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association、1994) [Table#2519]、Ethyl vanillin is used extensively in the chocolate industry. It gives a sweet、balsamic note to flowery and fruity perfume compositions.、Use Classification: Fragrance Ingredients、Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes、Flavoring Agents -> JECFA Flavorings Index、Cosmetics -> Soothing、Masking、Industry Uses: Fragrance、Flavoring and nutrient、Consumer Uses: Fragrance、Household Products: Information on 121 consumer products that contain Ethyl Vanillin in the following categories is provided:、• Auto Products、• Inside the Home、• Personal Care、Methods of Manufacturing: From safrole by isomerization to isosafrole and subsequent oxidation to piperonal、the methylene linkage is then broken by heating piperonal in an alcoholic solution of KOH、finally the resulting protocatechualdehyde is reacted with ethyl alcohol.、From guaethol by condensation with chloral to yield 3-ethoxy-4-hydroxyphenyl trichloromethyl carbinol、this is then boiled with an alcoholic solution of KOH or NaOH、acidified、and extracted with chloroform to yield ethyl vanillin.、By reacting o-ethoxyphenol with formaldehyde and p-nitrosodimethylaniline in the presence of aluminum and water.、Formulations、Preparations: Grades: National Formulary、Food Chemical Codex、Consumption Patterns: 100% AS A FLAVORING AGENT (1976)、U.S. Production: 2023: 10、000、000 - <25、000 lb、2022: 10、2021: 10、2020: 10、(1972) 1.27X10+7 GRAMS、(1975) GREATER THAN 4.5X10+7 GRAMS、Production volume for non-confidential chemicals reported under the 2006 Inventory Update Rule. Chemical: Benzaldehyde、3-ethoxy-4-hydroxy-. Aggregated National Production Volume: 1 to < 10 million pounds.、Non-confidential 2012 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: Benzaldehyde、3-ethoxy-4-hydroxy-. National Production Volume: 1、000 - 10、yr.、U.S. Imports: (1972) 6.93X10+7 GRAMS (PRINCPL CUSTMS DISTS)、(1976) 1.06X10+8 GRAMS (PRINCPL CUSTMS DISTS)、General Manufacturing Information: All Other Chemical Product and Preparation Manufacturing、Plastics Material and Resin Manufacturing、All Other Basic Organic Chemical Manufacturing、Food、beverage、and tobacco product manufacturing、Soap、Cleaning Compound、and Toilet Preparation Manufacturing、Benzaldehyde、3-ethoxy-4-hydroxy-: ACTIVE、The flavoring power is two to four times stronger than vanillin. |
登记用途：Uses: Used in perfumes、and organic synthesis、[HSDB]、In flavoring and perfumery、Used as a chemical intermediate、to replace or fortify vanillin.、Reported uses (ppm):、Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association、1994) [Table#2519]、Ethyl vanillin is used extensively in the chocolate industry. It gives a sweet、balsamic note to flowery and fruity perfume compositions.、Use Classification: Fragrance Ingredients、Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes、Flavoring Agents -> JECFA Flavorings Index、Cosmetics -> Soothing、Masking、Industry Uses: Fragrance、Flavoring and nutrient、Consumer Uses: Fragrance、Household Products: Information on 121 consumer products that contain Ethyl Vanillin in the following categories is provided:、• Auto Products、• Inside the Home、• Personal Care、Methods of Manufacturing: From safrole by isomerization to isosafrole and subsequent oxidation to piperonal、the methylene linkage is then broken by heating piperonal in an alcoholic solution of KOH、finally the resulting protocatechualdehyde is reacted with ethyl alcohol.、From guaethol by condensation with chloral to yield 3-ethoxy-4-hydroxyphenyl trichloromethyl carbinol、this is then boiled with an alcoholic solution of KOH or NaOH、acidified、and extracted with chloroform to yield ethyl vanillin.、By reacting o-ethoxyphenol with formaldehyde and p-nitrosodimethylaniline in the presence of aluminum and water.、Formulations、Preparations: Grades: National Formulary、Food Chemical Codex、Consumption Patterns: 100% AS A FLAVORING AGENT (1976)、U.S. Production: 2023: 10、000、000 - <25、000 lb、2022: 10、2021: 10、2020: 10、(1972) 1.27X10+7 GRAMS、(1975) GREATER THAN 4.5X10+7 GRAMS、Production volume for non-confidential chemicals reported under the 2006 Inventory Update Rule. Chemical: Benzaldehyde、3-ethoxy-4-hydroxy-. Aggregated National Production Volume: 1 to < 10 million pounds.、Non-confidential 2012 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: Benzaldehyde、3-ethoxy-4-hydroxy-. National Production Volume: 1、000 - 10、yr.、U.S. Imports: (1972) 6.93X10+7 GRAMS (PRINCPL CUSTMS DISTS)、(1976) 1.06X10+8 GRAMS (PRINCPL CUSTMS DISTS)、General Manufacturing Information: All Other Chemical Product and Preparation Manufacturing、Plastics Material and Resin Manufacturing、All Other Basic Organic Chemical Manufacturing、Food、beverage、and tobacco product manufacturing、Soap、Cleaning Compound、and Toilet Preparation Manufacturing、Benzaldehyde、3-ethoxy-4-hydroxy-: ACTIVE、The flavoring power is two to four times stronger than vanillin.。
乙基香兰素 FCC 是一种化工化合物，登记 CAS 号为 121-32-4，分子式 C9H10O3（分子量 166.17）。
登记 CAS 号：121-32-4
其分子式 C9H10O3 由 9 个碳、10 个氢、3 个氧 组成。
别名/同义词：乙基香兰素 FCC · Ethyl vanillin · 4-Hydroxy-3-ethoxybenzaldehyde · Ethyl Vanillin FCC
乙基香兰素 FCC 的 CAS 登记号为 121-32-4。
分子式 C9H10O3，分子量 166.17。
别名/同义词：乙基香兰素 FCC、Ethyl vanillin、4-Hydroxy-3-ethoxybenzaldehyde、Ethyl Vanillin FCC。
登记用途：Uses: Used in perfumes、and organic synthesis、[HSDB]、In flavoring and perfumery、Used as a chemical intermediate、to replace or fortify vanillin.、Reported uses (ppm):、Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association、1994) [Table#2519]、Ethyl vanillin is used extensively in the chocolate industry. It gives a sweet、balsamic note to flowery and fruity perfume compositions.、Use Classification: Fragrance Ingredients、Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes、Flavoring Agents -> JECFA Flavorings Index、Cosmetics -> Soothing、Masking、Industry Uses: Fragrance、Flavoring and nutrient、Consumer Uses: Fragrance、Household Products: Information on 121 consumer products that contain Ethyl Vanillin in the following categories is provided:、• Auto Products、• Inside the Home、• Personal Care、Methods of Manufacturing: From safrole by isomerization to isosafrole and subsequent oxidation to piperonal、the methylene linkage is then broken by heating piperonal in an alcoholic solution of KOH、finally the resulting protocatechualdehyde is reacted with ethyl alcohol.、From guaethol by condensation with chloral to yield 3-ethoxy-4-hydroxyphenyl trichloromethyl carbinol、this is then boiled with an alcoholic solution of KOH or NaOH、acidified、and extracted with chloroform to yield ethyl vanillin.、By reacting o-ethoxyphenol with formaldehyde and p-nitrosodimethylaniline in the presence of aluminum and water.、Formulations、Preparations: Grades: National Formulary、Food Chemical Codex、Consumption Patterns: 100% AS A FLAVORING AGENT (1976)、U.S. Production: 2023: 10、000、000 - <25、000 lb、2022: 10、2021: 10、2020: 10、(1972) 1.27X10+7 GRAMS、(1975) GREATER THAN 4.5X10+7 GRAMS、Production volume for non-confidential chemicals reported under the 2006 Inventory Update Rule. Chemical: Benzaldehyde、3-ethoxy-4-hydroxy-. Aggregated National Production Volume: 1 to < 10 million pounds.、Non-confidential 2012 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: Benzaldehyde、3-ethoxy-4-hydroxy-. National Production Volume: 1、000 - 10、yr.、U.S. Imports: (1972) 6.93X10+7 GRAMS (PRINCPL CUSTMS DISTS)、(1976) 1.06X10+8 GRAMS (PRINCPL CUSTMS DISTS)、General Manufacturing Information: All Other Chemical Product and Preparation Manufacturing、Plastics Material and Resin Manufacturing、All Other Basic Organic Chemical Manufacturing、Food、beverage、and tobacco product manufacturing、Soap、Cleaning Compound、and Toilet Preparation Manufacturing、Benzaldehyde、3-ethoxy-4-hydroxy-: ACTIVE、The flavoring power is two to four times stronger than vanillin.。
乙基香兰素 FCC（CAS 121-32-4）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 121-32-4 |
|---|---|
| PubChem CID | 8467 |
| Molecular formula | C9H10O3 |
| IUPAC name | 3-ethoxy-4-hydroxybenzaldehyde |
| UNII (FDA) | YC9ST449YJ |
| FEMA number | 2464 |
| JECFA number | 893 |
| Molecular Weight | 166.17 |
|---|---|
| XLogP3 | 1.6 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 3 |
| Exact Mass | 166.062994177 |
| Monoisotopic Mass | 166.062994177 |
| Topological Polar Surface Area | 46.5 |
| Heavy Atom Count | 12 |
| Boiling Point | 285 °C |
|---|---|
| Boiling Point | 285.00 to 294.00 °C. @ 760.00 mm Hg |
| Melting Point | 171 to 172 °F (NTP, 1992) |
| Melting Point | 76.7 °C |
| Melting Point | 76 - 78 °C |
| Flash Point | 145 °C (293 °F) - closed cup |
| Solubility | In water, 2,822 mg/L at 25 °C |
| Solubility | 2.82 mg/mL at 25 °C |
| Vapor Pressure | 0.0000104 [mmHg] |
| Vapor Pressure | 1.04X10-5 mm Hg at 25 °C |
3-Ethoxy-4-hydroxybenzaldehyde; ETHYL VANILLIN; Ethylvanillin; 121-32-4; Vanillal; Ethylprotal; Bourbonal; Ethavan; Ethovan; Vanirom; Vanilal; Quantrovanil; 4-Hydroxy-3-ethoxybenzaldehyde; Benzaldehyde, 3-ethoxy-4-hydroxy-; Rhodiarome; Vanillin, ethyl-
| Regulatory & Food Contact | EU Flavoring substances FDA Substance added to food: FLAVORING AGENT OR ADJUVANT, PH CONTROL AGENT Flavoring Agents FLAVOURING_AGENT: Flavouring Agent Floral 3-ETHOXY PROTOCATECHUALDEHYDE |
|---|---|
| GHS notification summary | 78.7% (1611 / 2046) |
| GHS notification summary | 78.7% (1611 / 2046) |
|---|---|
| Reported hazard statements | H319 (20.7%), H302, H315, H335, H402, H412 |
This chemical does not meet GHS hazard criteria for 78.7% (1611 of 2046) of all reports.
H319 (20.7%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
Ethyl Vanillin FCC · CAS 121-32-4 · C9H10O3. UNII YC9ST449YJ. Boiling Point: 285 °C; Boiling Point: 285.00 to 294.00 °C. @ 760.00 mm Hg; Melting Point: 171 to 172 °F (NTP, 1992).
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Ethyl vanillin