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硫酸长春碱

CAS 143-67-9C46H58N4O9MW 811.0

本页收录 硫酸长春碱,CAS 登记号为 143-67-9,分子式 C46H58N4O9,分子量 811.0,归类于无机化学品。作为主营产品之一,济南圣和化工有限公司 可提供从公斤级到吨级的稳定供货,随货附 COA 与质检资料。

产品概览

CAS号143-67-9
分子式C46H58N4O9
分子量811.0
熔点267
LogP3.7
纯度按批次COA提供(不公开发布)
包装按订单/批次确认(不公开发布)
应用领域无机化学品
类别无机化学品

应用领域

无机化学品

硫酸长春碱在无机化学品领域使用广泛。采购前请确认纯度等级与包装形式,以批次 COA 为验收依据。

包装与储存

包装规格按订单/批次确认(不公开发布)
纯度规格按批次COA提供(不公开发布)
储存条件密封、阴凉干燥处保存
运输常规化工运输
样品可协商提供
交期现货/按订单安排

供应说明:硫酸长春碱 常规包装为按订单/批次确认(不公开发布),储存时应密封置于阴凉干燥处,避免与氧化剂混放。济南圣和化工有限公司 支持国内物流发货,大货交期与运费以订单确认为准。

质量与文件

每批产品随货提供 COA(分析证书);可按需提供 MSDS/技术数据表及第三方检测报告。纯度与包装以批次 COA 及订单确认为准。

关于供应商

选择 济南圣和化工有限公司 的理由:产品信息透明(含 CAS、分子式、理化参数)、报价响应快(一个工作日内)、单证齐全(COA/MSS/质检资料按需提供)、支持批量与长期协议供货。如需 硫酸长春碱 以外的配套原料,也欢迎一并列出需求清单。

常见问题

硫酸长春碱 的 CAS 号是多少?

硫酸长春碱 的 CAS 号为 143-67-9。

该产品的纯度和包装规格是什么?

常规纯度规格为 按批次COA提供(不公开发布),包装为 按订单/批次确认(不公开发布),随货提供 COA。

硫酸长春碱 有什么用途?

主要应用于无机化学品。

如何购买或获取报价?

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PubChem 公开数据

Description

Vinblastine sulfate · CAS 143-67-9 · C46H58N4O9. UNII 5V9KLZ54CY. Melting Point: 267; Melting Point: 211-216 °C; LogP: 3.7.

Identification

CAS Registry Number143-67-9
PubChem CID13342
Molecular formulaC46H58N4O9
UNII (FDA)5V9KLZ54CY

Computed Descriptors

Molecular Weight811.0
XLogP33.7
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count12
Rotatable Bond Count10
Exact Mass810.42037944
Monoisotopic Mass810.42037944
Topological Polar Surface Area154
Heavy Atom Count59
Formal Charge0

Physical & Chemical Properties

Melting Point267
Melting Point211-216 °C
LogP3.7
LogPlog Kow = 3.70
LogP3.72
Dissociation ConstantspKa1 = 5.4; pKa2 = 7.4

Physical description & handling notes

  • Solvated needles from methanol
  • Negligible
  • ODORLESS & HYGROSCOPIC; WHITE TO SLIGHTLY YELLOW, AMORPHOUS OR CRYSTALLINE POWDER; FREELY SOL IN WATER /VINBLASTINE SULFATE/
  • Practically insoluble in water, petroleum ether; soluble in alcohols, acetone, ethyl acetate, chloroform
  • SOLN MAY BE STORED IN REFRIGERATOR FOR PERIODS OF 30 DAYS WITHOUT SIGNIFICANT LOSS OF POTENCY /VINBLASTINE SULFATE/
  • Crystallizes as hydrate, mp 284-285 °C. Specific optical rotation = - 28 deg at 26 °C/D ( c = 1.01 in methanol); UV max (Methanol): 212, 262, 282, 292 nm (log epsilon = 4.75, 4.28, 4.22, 4,18). Very slightly soluble in ethanol. Practically insoluble in ether. One part is soluble in 10 parts of water, 50 parts of chloroform /Sulfate/

Documented Uses

  • For treatment of breast cancer, testicular cancer, lymphomas, neuroblastoma, Hodgkin's and non-Hodgkin's lymphomas, mycosis fungoides, histiocytosis, and Kaposi's sarcoma.
  • ... in the treatment of Hodgkins disease /Vinblastine sulfate USP/
  • ... Isolated from periwinkle, Vinca rosea Linn, Apocynaceae.
  • BY EXTRACTING LEAVES, BARK, OR STEMS OF VINCA ROSEA ... ISOLATING ALKALOID ... BY PRECIPITATION & SOLVENT TECHNIQUES, & PURIFYING BY CHROMATOGRAPHY ... CONVERSION TO (1:1) SULFATE ... BY DISSOLVING ALKALOID IN EQUIMOLAR QUANTITY OF DILUTE SULFURIC ACID & ... EVAPORATING TO DRYNESS OR PRECIPITATING WITH SUITABLE ORG SOLVENT. /VINBLASTINE SULFATE/
  • Vinblastine and vincristine occur in Catharanthus roseus (L). The plant contains only very small amounts of vinblastine and vincristine, and their isolation is correspondingly difficult. First the alkaloids present are separated by extraction into alkaloid tartrate soluble in benzene and alkaloid tartrates insoluble in benzene. Vinblastine and vincristine belong to the first group. They then are separated by chromatography on aluminum oxide deactivated with acetic acid.
  • VINBLASTINE IS CLASS II IMMUNOSUPPRESSIVE DRUG, BUT IT HAS NOT BEEN EXPLOITED FOR THIS PURPOSE. /VINBLASTINE SULFATE/

Synonyms

vinblastine; 865-21-4; Vinblastin; Vincaleucoblastin; Vinblastina; Vincoblastine; Vincaleukoblastine; Nincaluicolflastine; Vinblastinum; Vincaleucoblastine; NCI-C04842; 5V9KLZ54CY; NSC 47842; NDC 0002-1452-01; NSC-47842; (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE

Frequently Asked Questions

What are the CAS number and molecular formula of Vinblastine sulfate?

CAS 143-67-9; molecular formula C46H58N4O9; molecular weight — g/mol.

What other names is Vinblastine sulfate known by?

vinblastine, 865-21-4, Vinblastin, Vincaleucoblastin, Vinblastina, Vincoblastine.

What are the key physical properties of Vinblastine sulfate?

Melting Point: 267; Melting Point: 211-216 °C; LogP: 3.7; LogP: log Kow = 3.70.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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English page: Vinblastine sulfate

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