丙戊酸

Description

2,2-Di-n-propylacetic acid · CAS 99-66-1 · C8H16O2. UNII 614OI1Z5WI. Boiling Point: 428 °F at 760 mmHg (NTP, 1992); Boiling Point: 222; Boiling Point: 219.5 °C.

Identification

CAS Registry Number	99-66-1
PubChem CID	3121
Molecular formula	C8H16O2
IUPAC name	2-propylpentanoic acid
UNII (FDA)	614OI1Z5WI

Computed Descriptors

Molecular Weight	144.21
XLogP3	2.8
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	5
Exact Mass	144.115029749
Monoisotopic Mass	144.115029749
Topological Polar Surface Area	37.3
Heavy Atom Count	10
Formal Charge	0

Physical & Chemical Properties

Boiling Point	428 °F at 760 mmHg (NTP, 1992)
Boiling Point	222
Boiling Point	219.5 °C
Boiling Point	BP: 219 to 220 °C
Boiling Point	222 °C
Flash Point	232 °F (NTP, 1992)
Solubility	1.3
Solubility	In water, 2.0X10+3 mg/L at 20 °C
Solubility	2 mg/mL at 20 °C
Density	0.904 g/cu cm at 25 °C

Physical description & handling notes

• Valproic acid is a clear colorless liquid. (NTP, 1992)
• Liquid
• Colorless liquid
• Characteristic odor
• less than 1 mg/mL at 72 °F (NTP, 1992)
• Very soluble in organic solvents

GHS Hazard Classification

Reported hazard statements	H302 (100%), H315 (92.9%), H318 (12.7%), H319 (80.2%), H335 (31.7%), H360 (64.3%), H336, H362

Documented Uses

• Indicated as monotherapy and adjunctive therapy in the treatment of patients with complex partial seizures that occur in either isolation or association with other types of seizures
• THERAPEUTIC CATEGORY (VETERINARY): Anticonvulsant
• Anticonvulsants; Antimanic Agents; Enzyme Inhibitors; GABA Agents
• Use (kg) in Switzerland (2009): >7500
• Use (kg; approx.) in Germany (2009): >75000
• Use (kg; exact) in Germany (2009): 94896

Synonyms

VALPROIC ACID; 2-Propylpentanoic acid; 99-66-1; 2-Propylvaleric acid; Dipropylacetic acid; Depakene; Depakine; Mylproin; Di-n-propylacetic acid; Propylvaleric acid; n-Dipropylacetic acid; 4-Heptanecarboxylic acid; Myproic Acid; Convulex; n-DPA; Acido valproico

Frequently Asked Questions

What are the CAS number and molecular formula of 2,2-Di-n-propylacetic acid?

CAS 99-66-1; molecular formula C8H16O2; molecular weight — g/mol.

What other names is 2,2-Di-n-propylacetic acid known by?

VALPROIC ACID, 2-Propylpentanoic acid, 99-66-1, 2-Propylvaleric acid, Dipropylacetic acid, Depakene.

Is 2,2-Di-n-propylacetic acid classified as hazardous?

Hazard statements reported: H302, H315, H318, H319, H335.

What are the key physical properties of 2,2-Di-n-propylacetic acid?

Boiling Point: 428 °F at 760 mmHg (NTP, 1992); Boiling Point: 222; Boiling Point: 219.5 °C; Boiling Point: BP: 219 to 220 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.