Glibenclamide (CAS 10238-21-8) — formula C23H28ClN3O5S, molecular weight 494.0; category pharmaceutical intermediates and APIs.
Glibenclamide (CAS 10238-21-8) is a chemical raw material in the pharmaceutical intermediates and APIs category. Its molecular formula C23H28ClN3O5S comprises 23 C, 28 H, 1 Cl, 3 N, 5 O, 1 S atoms. Its molecular weight is about 494.0. Reported physicochemical data: melting point around 169, LogP about 3.754. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.
| CAS Number | 10238-21-8 |
|---|---|
| Molecular Formula | C23H28ClN3O5S |
| Molecular Weight | 494.0 |
| Melting Point | 169 |
| LogP | 3.754 |
| Applications | Use (kg, approx.) in Germany (2009): >750, Use (kg) in USA (2002): 3590, Use (kg) in France (2004): 1092, Consumption (g per capita, approx.) in Germany (2009): 0.00916 |
| Category | Pharmaceutical Intermediates & APIs |
Documented applications: Use (kg, approx.) in Germany (2009): >750, Use (kg) in USA (2002): 3590, Use (kg) in France (2004): 1092, Consumption (g per capita, approx.) in Germany (2009): 0.00916.
Glibenclamide is a pharmaceutical intermediate or API compound with CAS registry number 10238-21-8 and molecular formula C23H28ClN3O5S (molecular weight 494.0), belonging to the pharmaceutical intermediates and APIs segment of chemical raw materials.
CAS number: 10238-21-8
Its molecular formula C23H28ClN3O5S comprises 23 C, 28 H, 1 Cl, 3 N, 5 O, 1 S atoms.
Also known as: Glibenclamide · 格列本脲 · Glybenzcyclamide
Category: pharmaceutical intermediates and APIs
The CAS registry number of Glibenclamide is 10238-21-8.
Molecular formula C23H28ClN3O5S, molecular weight 494.0.
It is also registered under: Glibenclamide, 格列本脲, Glybenzcyclamide.
Recorded applications: Use (kg, approx.) in Germany (2009): >750, Use (kg) in USA (2002): 3590, Use (kg) in France (2004): 1092, Consumption (g per capita, approx.) in Germany (2009): 0.00916.
Category: Pharmaceutical Intermediates & APIs.
Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.
Independent reference data for Glibenclamide (CAS 10238-21-8), compiled from public chemistry databases.
| CAS Registry Number | 10238-21-8 |
|---|---|
| PubChem CID | 3488 |
| Molecular formula | C23H28ClN3O5S |
| IUPAC name | 5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide |
| UNII (FDA) | SX6K58TVWC |
| Molecular Weight | 494.0 |
|---|---|
| XLogP3 | 4.8 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 8 |
| Exact Mass | 493.1438199 |
| Monoisotopic Mass | 493.1438199 |
| Topological Polar Surface Area | 122 |
| Heavy Atom Count | 33 |
| Melting Point | 169 |
|---|---|
| Melting Point | 169 - 170 °C |
| Solubility | 2.06e-03 g/L |
| LogP | 3.754 |
| LogP | 4.7 |
| LogP | 3.09 |
Glibenclamide; glyburide; 10238-21-8; Glynase; Euglucon; Semi-daonil; Libanil; Calabren; Lederglib; Glibenclamida; Glibenclamidum; Glyburide (micronized); HB 419; 1-(p-(2-(5-Chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylurea; 5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide; Gliken
| GHS notification summary | 1.1% (1 / 95) |
|---|
| GHS notification summary | 1.1% (1 / 95) |
|---|---|
| Reported hazard statements | H302 (89.5%), H413 (93.7%) |
This chemical does not meet GHS hazard criteria for 1.1% (1 of 95) of reports.
H302 (89.5%): Harmful if swallowed [Warning Acute toxicity, oral]
Glybenzcyclamide · CAS 10238-21-8 · C23H28ClN3O5S. UNII SX6K58TVWC. Melting Point: 169; Melting Point: 169 - 170 °C; Solubility: 2.06e-03 g/L.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 甘草酰胺