荧光素钠(CAS 518-47-8):分子式 C20H10Na2O5、分子量 376.3。
| CAS号 | 518-47-8 |
|---|---|
| 分子式 | C20H10Na2O5 |
| 分子量 | 376.3 |
| 应用领域 | Uses: Used in analysis of subterranean waters、as a reagent (protein label、immunohistological stain、and immunofluorescent label)、diagnostic aid (corneal abrasions)、and for ophthalmic angiography and contact lens fitting、[Merck Index] Used as a marker for sea rescues、for dyeing silk and wool、to make fluorescent laminates、and in commercial antifreezes、[HSDB] Permitted for use as an inert ingredient in non-food pesticide products、[EPA]、Textiles (Printing、Dyeing、or Finishing) [Category: Industry]、Highly purified product is used in solution as a diagnostic aid for evaluating corneal trauma and for treating intraocular inflammation.、Because of its intense fluorescence and、non-、biodegradability、it is in great demand for tracing the course of underground streams and of factory effluents and sewage sources that contaminate underground water supplies.、As a marker for sea-rescue operations、Dyeing silk and wool yellow、For more Uses (Complete) data for D&C Yellow No. 8 (9 total)、please visit the HSDB record page.、Use Classification: Cosmetics -> Hair dyeing、Cosmetic colorant、Consumer Uses: Not Known or Reasonably Ascertainable、Household Products: Information on 19 consumer products that contain D&C Yellow #8 (C.I. 45350) in the following categories is provided:、• Auto Products、• Commercial、Institutional、• Inside the Home、• Personal Care、Methods of Manufacturing: By treatment of fluorescein with sodium carbonate solution and crystallizing.、Formulations、Preparations: Grades: Technical、USP (as sodium fluorescein)、Trade names: C.I. Acid Yellow 73、Fluor-I-strip A.T.、Ful-Glo、12417 Yellow、11824 Yellow、Fluorescite (fluorescein injection、USP) 10% contains fluorescein sodium (equivalent to fluorescein 10% w、v).、Ak-Fluor (fluorescein injection、USP) 10% is 100 mg、mL in a 5 mL single vial and Ak-Fluor (fluorescein injection、USP) 25% is 250 mg、mL in a 2 mL single dose vial、U.S. Production: 2023: 35、700 lb、2022: 38、600 lb、2021: 11、100 lb、2020: 611 lb、Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#7954]、[US EPA、Non-confidential Production Volume Information Submitted by Companies for Chemicals Under the 1986-2002 Inventory Update Rule (IUR). Spiro[isobenzofuran-1(3H)、9'-、General Manufacturing Information: Spiro[isobenzofuran-1(3H)、9'-[9H]xanthen]-3-one、3'、6'-dihydroxy-、sodium salt (1:2): ACTIVE、The name D&C Yellow No. 8 can be used only when applied to batches of color that have been certified according to the United States certification regulations. The CFTA Adopted Name for non-certified batches of this color is Acid Yellow 73 Sodium Salt.、Color additives were initially regulated in the United States under the U.S. Department of Agriculture's (USDA) Bureau of Chemistry. In 1906、the Food and Drugs Act was passed by Congress、which prohibited the use of poisonous or deleterious colors in confectionery and the coloring or staining of food to conceal damage or inferiority. In 1927、responsibility of the Food and Drugs Act was transferred to FDA. Increasing government oversight、the Federal Food、Drug、and Cosmetic Act (FFDCA) was passed in 1938 and established the three following categories for colors: FD&C: colors used in foods、drugs and cosmetics、D&C: colors used in drugs and cosmetics when in contact with mucous membranes or ingested、and Ext. D&C: colors used in products applied externally.、Serves to ascertain source of springs、connections between streams and sea、determining approximate volume of water delivered by a spring、detecting source of contamination of drinking water、infiltration of soil with waste waters of factories.、Fluorescein disodium、Incompatibility: ... not compatible with effective preservatives such as benzalkonium chloride or substances known to be effective against Pseudomonas aeruginosa、such as polymyxin B sulfate. |
登记用途:Uses: Used in analysis of subterranean waters、as a reagent (protein label、immunohistological stain、and immunofluorescent label)、diagnostic aid (corneal abrasions)、and for ophthalmic angiography and contact lens fitting、[Merck Index] Used as a marker for sea rescues、for dyeing silk and wool、to make fluorescent laminates、and in commercial antifreezes、[HSDB] Permitted for use as an inert ingredient in non-food pesticide products、[EPA]、Textiles (Printing、Dyeing、or Finishing) [Category: Industry]、Highly purified product is used in solution as a diagnostic aid for evaluating corneal trauma and for treating intraocular inflammation.、Because of its intense fluorescence and、non-、biodegradability、it is in great demand for tracing the course of underground streams and of factory effluents and sewage sources that contaminate underground water supplies.、As a marker for sea-rescue operations、Dyeing silk and wool yellow、For more Uses (Complete) data for D&C Yellow No. 8 (9 total)、please visit the HSDB record page.、Use Classification: Cosmetics -> Hair dyeing、Cosmetic colorant、Consumer Uses: Not Known or Reasonably Ascertainable、Household Products: Information on 19 consumer products that contain D&C Yellow #8 (C.I. 45350) in the following categories is provided:、• Auto Products、• Commercial、Institutional、• Inside the Home、• Personal Care、Methods of Manufacturing: By treatment of fluorescein with sodium carbonate solution and crystallizing.、Formulations、Preparations: Grades: Technical、USP (as sodium fluorescein)、Trade names: C.I. Acid Yellow 73、Fluor-I-strip A.T.、Ful-Glo、12417 Yellow、11824 Yellow、Fluorescite (fluorescein injection、USP) 10% contains fluorescein sodium (equivalent to fluorescein 10% w、v).、Ak-Fluor (fluorescein injection、USP) 10% is 100 mg、mL in a 5 mL single vial and Ak-Fluor (fluorescein injection、USP) 25% is 250 mg、mL in a 2 mL single dose vial、U.S. Production: 2023: 35、700 lb、2022: 38、600 lb、2021: 11、100 lb、2020: 611 lb、Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#7954]、[US EPA、Non-confidential Production Volume Information Submitted by Companies for Chemicals Under the 1986-2002 Inventory Update Rule (IUR). Spiro[isobenzofuran-1(3H)、9'-、General Manufacturing Information: Spiro[isobenzofuran-1(3H)、9'-[9H]xanthen]-3-one、3'、6'-dihydroxy-、sodium salt (1:2): ACTIVE、The name D&C Yellow No. 8 can be used only when applied to batches of color that have been certified according to the United States certification regulations. The CFTA Adopted Name for non-certified batches of this color is Acid Yellow 73 Sodium Salt.、Color additives were initially regulated in the United States under the U.S. Department of Agriculture's (USDA) Bureau of Chemistry. In 1906、the Food and Drugs Act was passed by Congress、which prohibited the use of poisonous or deleterious colors in confectionery and the coloring or staining of food to conceal damage or inferiority. In 1927、responsibility of the Food and Drugs Act was transferred to FDA. Increasing government oversight、the Federal Food、Drug、and Cosmetic Act (FFDCA) was passed in 1938 and established the three following categories for colors: FD&C: colors used in foods、drugs and cosmetics、D&C: colors used in drugs and cosmetics when in contact with mucous membranes or ingested、and Ext. D&C: colors used in products applied externally.、Serves to ascertain source of springs、connections between streams and sea、determining approximate volume of water delivered by a spring、detecting source of contamination of drinking water、infiltration of soil with waste waters of factories.、Fluorescein disodium、Incompatibility: ... not compatible with effective preservatives such as benzalkonium chloride or substances known to be effective against Pseudomonas aeruginosa、such as polymyxin B sulfate.。
荧光素钠 是一种化工化合物,登记 CAS 号为 518-47-8,分子式 C20H10Na2O5(分子量 376.3)。
登记 CAS 号:518-47-8
其分子式 C20H10Na2O5 由 20 个碳、10 个氢、2 个钠、5 个氧 组成。
别名/同义词:荧光素钠 · Fluorescein sodium
荧光素钠 的 CAS 登记号为 518-47-8。
分子式 C20H10Na2O5,分子量 376.3。
别名/同义词:荧光素钠、Fluorescein sodium。
登记用途:Uses: Used in analysis of subterranean waters、as a reagent (protein label、immunohistological stain、and immunofluorescent label)、diagnostic aid (corneal abrasions)、and for ophthalmic angiography and contact lens fitting、[Merck Index] Used as a marker for sea rescues、for dyeing silk and wool、to make fluorescent laminates、and in commercial antifreezes、[HSDB] Permitted for use as an inert ingredient in non-food pesticide products、[EPA]、Textiles (Printing、Dyeing、or Finishing) [Category: Industry]、Highly purified product is used in solution as a diagnostic aid for evaluating corneal trauma and for treating intraocular inflammation.、Because of its intense fluorescence and、non-、biodegradability、it is in great demand for tracing the course of underground streams and of factory effluents and sewage sources that contaminate underground water supplies.、As a marker for sea-rescue operations、Dyeing silk and wool yellow、For more Uses (Complete) data for D&C Yellow No. 8 (9 total)、please visit the HSDB record page.、Use Classification: Cosmetics -> Hair dyeing、Cosmetic colorant、Consumer Uses: Not Known or Reasonably Ascertainable、Household Products: Information on 19 consumer products that contain D&C Yellow #8 (C.I. 45350) in the following categories is provided:、• Auto Products、• Commercial、Institutional、• Inside the Home、• Personal Care、Methods of Manufacturing: By treatment of fluorescein with sodium carbonate solution and crystallizing.、Formulations、Preparations: Grades: Technical、USP (as sodium fluorescein)、Trade names: C.I. Acid Yellow 73、Fluor-I-strip A.T.、Ful-Glo、12417 Yellow、11824 Yellow、Fluorescite (fluorescein injection、USP) 10% contains fluorescein sodium (equivalent to fluorescein 10% w、v).、Ak-Fluor (fluorescein injection、USP) 10% is 100 mg、mL in a 5 mL single vial and Ak-Fluor (fluorescein injection、USP) 25% is 250 mg、mL in a 2 mL single dose vial、U.S. Production: 2023: 35、700 lb、2022: 38、600 lb、2021: 11、100 lb、2020: 611 lb、Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#7954]、[US EPA、Non-confidential Production Volume Information Submitted by Companies for Chemicals Under the 1986-2002 Inventory Update Rule (IUR). Spiro[isobenzofuran-1(3H)、9'-、General Manufacturing Information: Spiro[isobenzofuran-1(3H)、9'-[9H]xanthen]-3-one、3'、6'-dihydroxy-、sodium salt (1:2): ACTIVE、The name D&C Yellow No. 8 can be used only when applied to batches of color that have been certified according to the United States certification regulations. The CFTA Adopted Name for non-certified batches of this color is Acid Yellow 73 Sodium Salt.、Color additives were initially regulated in the United States under the U.S. Department of Agriculture's (USDA) Bureau of Chemistry. In 1906、the Food and Drugs Act was passed by Congress、which prohibited the use of poisonous or deleterious colors in confectionery and the coloring or staining of food to conceal damage or inferiority. In 1927、responsibility of the Food and Drugs Act was transferred to FDA. Increasing government oversight、the Federal Food、Drug、and Cosmetic Act (FFDCA) was passed in 1938 and established the three following categories for colors: FD&C: colors used in foods、drugs and cosmetics、D&C: colors used in drugs and cosmetics when in contact with mucous membranes or ingested、and Ext. D&C: colors used in products applied externally.、Serves to ascertain source of springs、connections between streams and sea、determining approximate volume of water delivered by a spring、detecting source of contamination of drinking water、infiltration of soil with waste waters of factories.、Fluorescein disodium、Incompatibility: ... not compatible with effective preservatives such as benzalkonium chloride or substances known to be effective against Pseudomonas aeruginosa、such as polymyxin B sulfate.。
荧光素钠(CAS 518-47-8)的独立参考数据,整理自公开化学数据库。
| CAS Registry Number | 518-47-8 |
|---|---|
| PubChem CID | 10608 |
| Molecular formula | C20H10Na2O5 |
| IUPAC name | disodium;2-(3-oxido-6-oxoxanthen-9-yl)benzoate |
| UNII (FDA) | 93X55PE38X |
| Molecular Weight | 376.3 |
|---|---|
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 1 |
| Exact Mass | 376.03236198 |
| Monoisotopic Mass | 376.03236198 |
| Topological Polar Surface Area | 89.5 |
| Heavy Atom Count | 27 |
| Color Additive Status | 74.1708 |
|---|---|
| Color Additive Status | 74.2708 |
| Color Additive Status | 74.3708 |
| Color Additive Status | 82.1708 |
Fluorescein disodium salt; Soluble fluorescein; Sodium fluorescein; Uranin; Uranine WSS; Resorcinol phthalein sodium; Uranine Yellow; Ak-Fluor; Fluorescein, soluble; Ki202; Sodium fluoresceinate; Fluoresceinum natricum; 93X55PE38X; D&C Yellow No. 8; Funduscein-25; Ki202(1)
| Regulatory & Food Contact | FDA Regulatory Status of Color Additives: Drugs, Cosmetics, Devices FDA Cumulative Estimated Daily Intake (CEDI): FCS CIR / INCI: Hair dyeing; Cosmetic colorant |
|---|---|
| GHS notification summary | 87.1% (263 / 302) |
| GHS notification summary | 87.1% (263 / 302) |
|---|---|
| Reported hazard statements | H315 (10.6%), H319 (11.3%) |
This chemical does not meet GHS hazard criteria for 87.1% (263 of 302) of all reports.
H315 (10.6%): Causes skin irritation [Warning Skin corrosion/irritation]
Fluorescein sodium · CAS 518-47-8 · C20H10Na2O5. UNII 93X55PE38X. Color Additive Status: 74.1708; Color Additive Status: 74.2708; Color Additive Status: 74.3708.
数据来源:PubChem / Wikidata;与随货 COA 不一致时以 COA 为准。
English page: Fluorescein sodium