对氨基苯甲酸正丁酯

Description

n-Butyl-p-Aminobenzoate · CAS 94-25-7 · C11H15NO2. UNII EFW857872Q. Boiling Point: 343 to 345 °F at 8 mmHg (NTP, 1992); Boiling Point: 173.5; Boiling Point: 173-174 °C @ 8 mm Hg.

Identification

CAS Registry Number	94-25-7
PubChem CID	2482
Molecular formula	C11H15NO2
IUPAC name	butyl 4-aminobenzoate
UNII (FDA)	EFW857872Q

Computed Descriptors

Molecular Weight	193.24
XLogP3	2.9
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	5
Exact Mass	193.110278721
Monoisotopic Mass	193.110278721
Topological Polar Surface Area	52.3
Heavy Atom Count	14
Formal Charge	0

Physical & Chemical Properties

Boiling Point	343 to 345 °F at 8 mmHg (NTP, 1992)
Boiling Point	173.5
Boiling Point	173-174 °C @ 8 mm Hg
Melting Point	136 °F (NTP, 1992)
Melting Point	58
Melting Point	58 °C
Solubility	140
Solubility	In water, 3.35X10+2 mg/l @ 25 °C
Vapor Pressure	0.000299 [mmHg]
LogP	2.87

Physical description & handling notes

• N-butyl-p-aminobenzoate is a yellow powder. Insoluble in water. (NTP, 1992)
• White odorless solid; Nearly insoluble in water; [Hawley] Yellow solid; Insoluble in water; [CAMEO] Faintly beige fine crystals; [MSDSonline]
• Crystals from alc
• White powder
• White, amorphous powder
• Odorless

GHS Hazard Classification

Reported hazard statements	H315 (100%), H317 (95.3%), H319 (100%), H335 (95.3%)

Documented Uses

• Used as a local anesthetic and in burn treatment ointments and suntan preparations; [Hawley] Used essentially 100% as a local anesthetic; [HSDB]
• ESTERIFICATION OF P-NITROBENZOIC ACID WITH N-BUTYL ALCOHOL FOLLOWED BY REDUCTION WITH IRON FILINGS AND HYDROCHLORIC ACID
• PREPARED BY ESTERIFYING P-NITROBENZOIC ACID WITH N-BUTYL ALCOHOL & REDUCING NITRO GROUP TO AMINO GROUP WITH IRON FILINGS & HCL.
• Prepn: Brill, J. Am. Chem. Soic. 43, 1322 (1921); Adams, Volwiler, U.S. pat 1,440,652 (1923 to Abbott); Brit. pat. 252,870; C.A. 17, 1243 (1923); C.A. 21, 2478 (1927).
• Produced by the esterification of 4-nitrobenzoyl chloride with n-butanol and reduction of the resulting nitroester.
• ESSENTIALLY 100% AS AN ANESTHETIC

Synonyms

Butyl 4-aminobenzoate; butamben; 94-25-7; Butesine; Butoform; Butyl aminobenzoate; Butylcaine; Planoform; Scuroform; Scuroforme; 4-(Butoxycarbonyl)aniline; Butyl keloform; Benzoic acid, 4-amino-, butyl ester; N-Butyl p-aminobenzoate; p-Aminobenzoic acid butyl ester; 4-Aminobenzoic acid butyl ester

Frequently Asked Questions

What are the CAS number and molecular formula of n-Butyl-p-Aminobenzoate?

CAS 94-25-7; molecular formula C11H15NO2; molecular weight — g/mol.

What other names is n-Butyl-p-Aminobenzoate known by?

Butyl 4-aminobenzoate, butamben, 94-25-7, Butesine, Butoform, Butyl aminobenzoate.

Is n-Butyl-p-Aminobenzoate classified as hazardous?

Hazard statements reported: H315, H317, H319, H335.

What are the key physical properties of n-Butyl-p-Aminobenzoate?

Boiling Point: 343 to 345 °F at 8 mmHg (NTP, 1992); Boiling Point: 173.5; Boiling Point: 173-174 °C @ 8 mm Hg; Melting Point: 136 °F (NTP, 1992).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.