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Description

Acetamide Reagent · CAS 60-35-5 · C2H5NO. UNII 8XOE1JSO29. Boiling Point: 430 °F at 760 mmHg (NTP, 1992); Boiling Point: 222; Boiling Point: 222 °C at 760 mm Hg.

Identification

CAS Registry Number	60-35-5
PubChem CID	178
Molecular formula	C2H5NO
IUPAC name	acetamide
UNII (FDA)	8XOE1JSO29
JECFA number	1592

Computed Descriptors

Molecular Weight	59.07
XLogP3	-0.9
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	0
Exact Mass	59.037113783
Monoisotopic Mass	59.037113783
Topological Polar Surface Area	43.1
Heavy Atom Count	4
Formal Charge	0

Physical & Chemical Properties

Boiling Point	430 °F at 760 mmHg (NTP, 1992)
Boiling Point	222
Boiling Point	222 °C at 760 mm Hg
Boiling Point	221.00 to 222.00 °C. @ 760.00 mm Hg
Boiling Point	222 °C
Boiling Point	430 °F
Boiling Point	221 °C @760 [mm Hg]
Melting Point	180.1 °F (NTP, 1992)
Melting Point	81
Melting Point	81.16 °C

Physical description & handling notes

• Acetamide appears as colorless crystals with a mousy odor (NTP, 1999). Low toxicity.
• Colorless, deliquescent solid; [Hawley] Colorless crystals; [MSDSonline]
• Solid
• COLOURLESS DELIQUESCENT CRYSTALS.
• Colorless crystals
• Deliquescent hexagonal crystals

Regulatory Status

Regulatory & Food Contact	FDA Substance added to food: FLAVORING AGENT OR ADJUVANT FLAVOURING_AGENT: Flavouring Agent ACETAMIDE--NLFG TRS 934-JECFA 65/89 FAS 56-JECFA 65

GHS Hazard Classification

Reported hazard statements	H351, H361, H320, H316

Documented Uses

• Acetamide is used as a solvent, plasticizer, and a wetting and penetrating agent.
• Used as a solvent, plasticizer, stabilizer, humectant for paper, hygroscopic agent, wetting agent, penetrating agent, and denaturant of alcohol; Also used in lacquers, explosives, and soldering fluxes; [HSDB] Used as a solvent in the following applications: plasticizers, lacquers, explosives, soldering flux, wetting agents, and synthesis of other agents; [ACGIH]
• Soldering [Category: Heat or Machine]
• Pulp and Paper Processing [Category: Industry]
• Painting (Solvents) [Category: Paint]
• Solvent; molten acetamide is an excellent solvent for many organic and inorganic compounds. Solubilizer; renders sparingly soluble substances more soluble in water by mere addition or by fusion. Plasticizer; stabilizer. Manufacture of methylamine, denaturing alcohol. In organic synthesis.

Synonyms

acetamide; 60-35-5; Ethanamide; Acetic acid amide; Methanecarboxamide; Acetimidic acid; Ethanimidic acid; Amid kyseliny octove; NCI-C02108; CH3CONH2; DTXSID7020005; AI3-02060; 8XOE1JSO29; NSC 25945; NSC-25945; DTXCID505

Frequently Asked Questions

What are the CAS number and molecular formula of Acetamide Reagent?

CAS 60-35-5; molecular formula C2H5NO; molecular weight — g/mol.

What other names is Acetamide Reagent known by?

acetamide, 60-35-5, Ethanamide, Acetic acid amide, Methanecarboxamide, Acetimidic acid.

What is the regulatory status of Acetamide Reagent?

Documented regulatory listings: FDA Substance added to food: FLAVORING AGENT OR ADJUVANT; FLAVOURING_AGENT: Flavouring Agent; ACETAMIDE--NLFG.

Is Acetamide Reagent classified as hazardous?

Hazard statements reported: H351, H361, H320, H316.

What are the key physical properties of Acetamide Reagent?

Boiling Point: 430 °F at 760 mmHg (NTP, 1992); Boiling Point: 222; Boiling Point: 222 °C at 760 mm Hg; Boiling Point: 221.00 to 222.00 °C. @ 760.00 mm Hg.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.