N-亚硝基苯羟胺

Description

N-Nitrosophenylhydroxylamine · CAS 135-20-6 · C6H6N2O2.H3N. UNII V66QK963ED. Melting Point: 325 to 327 °F (NTP, 1992); Melting Point: 163.5 °C; Vapor Pressure: 0.0000629 [mmHg].

Identification

CAS Registry Number	135-20-6
PubChem CID	2724103
Molecular formula	C6H6N2O2.H3N
IUPAC name	azanium N-oxido-N-phenylnitrous amide
UNII (FDA)	V66QK963ED

Computed Descriptors

Molecular Weight	155.15
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	1
Exact Mass	155.069476538
Monoisotopic Mass	155.069476538
Topological Polar Surface Area	56.7
Heavy Atom Count	11
Formal Charge	0
Complexity	112

Physical & Chemical Properties

Melting Point	325 to 327 °F (NTP, 1992)
Melting Point	163.5 °C
Vapor Pressure	0.0000629 [mmHg]

Physical description & handling notes

• Cupferron appears as light yellow or cream-colored crystals or a brown crystalline solid. As a reagent in the separation of copper and iron.
• Creamy-white solid; [HSDB] Light yellow, cream-colored, or brown solid; Hygroscopic; [CAMEO] Pale yellow, odorless crystalline solid; [Alfa Aesar MSDS]
• Crystals
• Creamy-white crystals
• less than 1 mg/mL at 65.3 °F (NTP, 1992)
• Freely soluble in water

GHS Hazard Classification

Reported hazard statements	H301 (98%), H315 (98%), H319 (100%), H335 (86%), H351 (94%), H350, H373

Documented Uses

• Used as an analytical reagent for separation and precipitation of metals and a quantitative reagent for vanadates, titanium, and colorimetric estimation of aluminum; [HSDB]
• As a reagent for separating Sn from Zn, and Cu from Fe from other metals. Precipitates iron quantitatively from strongly acid solution; as a quantitative reagent for vanadates with which it gives a dark-rep precipitate solution in alkali solution, for Ti with which it form as a yellow precipitate; also suitable for the coloration estimation of Al.
• Reagent chemical ... manufactured to high and well-defined standards of purity
• By treating an ether solution of beta-phenylhydroxylamine with dry ammonia gas and amyl nitrite.
• REACTION OF PHENYLHYDROXYLAMINE WITH SODIUM NITRITE IN THE PRESENCE OF HYDROCHLORIC ACID, FOLLOWED BY TREATMENT WITH AMMONIA; TREATMENT OF PHENYLHYDROXYLAMINE WITH BUTYL OR AMYL NITRITE AND AMMONIA
• Prepared from phenylhydroxylamine by treating with NaNO2 at 0 °C in presence of HCl, filtering, dissolving in ether and treating with NH3, or by treating an ether solution of phenylhydroxylamine with butyl or amyl nitrite and NH3 in the cold.

Synonyms

CUPFERRON; 135-20-6; Cupferon; Kupferon; Ammonium cupferron; Ammonium-N-nitrosophenylhydroxylamine; N-Nitrosophenylhydroxylamine ammonium salt; Cupferron, ammonium salt; N-Nitroso-N-phenylhydroxylamine ammonium salt; DTXCID90352; N-Nitrosofenylhydroxylamin amonny; NCI-C03258; Ammonium N-nitrosophenylhydroxylamine; NSC-112124; Ammonium nitroso-beta-phenylhydroxylamine; N-Nitrosophenylhydroxylamin ammonium salz

Frequently Asked Questions

What are the CAS number and molecular formula of N-Nitrosophenylhydroxylamine?

CAS 135-20-6; molecular formula C6H6N2O2.H3N; molecular weight — g/mol.

What other names is N-Nitrosophenylhydroxylamine known by?

CUPFERRON, 135-20-6, Cupferon, Kupferon, Ammonium cupferron, Ammonium-N-nitrosophenylhydroxylamine.

Is N-Nitrosophenylhydroxylamine classified as hazardous?

Hazard statements reported: H301, H315, H319, H335, H351.

What are the key physical properties of N-Nitrosophenylhydroxylamine?

Melting Point: 325 to 327 °F (NTP, 1992); Melting Point: 163.5 °C; Vapor Pressure: 0.0000629 [mmHg].

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.