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氯菊酯

CAS 93389-07-2C21H20Cl2O3MW 391.3

氯菊酯(CAS 93389-07-2):分子式 C21H20Cl2O3、分子量 391.3。

产品概览

CAS号93389-07-2
分子式C21H20Cl2O3
分子量391.3
熔点34
沸点220
LogP6.5
应用领域Uses: Used as an ectoparasiticide in humans and animals、[Merck Index] Used as a nematocide、acaricide、and insecticide、[Hawley]、Farming (Pesticides) [Category: Industry]、For permethrin (USEPA、OPP Pesticide Code: 109701) ACTIVE products with label matches.、SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal、state and local authorities must be consulted for currently approved uses.、The pyrethroids are the most widely used class of insecticides in wood preservation because of their broad-spectrum activity、high efficacy especially against wood boring beetle、and high resistance to leaching.、Synthetic pyrethroids、Insecticide、seed treatment、protectant.、It has a potential application for forest protection and vector control for the control of noxious insects in the household and on cattle、for the control of body lice、and in mosquito nets.、For more Uses (Complete) data for PERMETHRIN (12 total)、please visit the HSDB record page.、Use (kg、approx.) in Germany (2009): >250、Consumption (g per capita、approx.) in Germany (2009): 0.00305、Calculated removal (%): 97.4、For the treatment of infestation with <i>Sarcoptes scabiei<、i> (scabies). Pyrethroids are used as insecticides. (L857)、Use Classification: Veterinary Drug -> INSECTICIDE -> JECFA Functional Classes、INSECTICIDES、Household Products: Cosmetics product ingredient: Permethrin (including cis- and trans-)、Source: Permethrin is a synthetic chemical used as a pesticide and insect repellent. It is used in agriculture、veterinary health、and medication. Permethrin may be added to lotions intended to treat scabies (a skin infection caused by mites)、and to sprays and shampoos used for lice control.、Potential health impacts: People may be exposed to permethrin by inhalation、ingestion、or through skin contact. Studies of scabies patients have found that dermal absorption of permethrin is low、but permethrin application may cause skin irritation. Inhaling permethrin may cause headache、nasal and respiratory irritation、dizziness、and nausea or vomiting. Studies of mice fed permethrin found increased rates of benign lung and liver tumors. The U.S. Environmental Protection Agency (U.S. EPA) classifies permethrin as likely to be carcinogenic to humans when ingested.、Product count: 2、Information on 256 consumer products that contain Permethrin in the following categories is provided:、• Commercial、Institutional、• Inside the Home、• Landscaping、Yard、• Personal Care、• Pesticides、• Pet Care、Methods of Manufacturing: Permethrin can be produced by condensation of 3-phenoxybenzyl alcohol with (1RS)-cis、trans-3-(2、2-dichlorovinyl)-2、2-dimethylcyclopropanecarboxylic acid.、The starting acid is prepared by a variation of the conventional chrysanthemic acid synthesis using ethyldiazoacetate in which 1、1-dichloro-4-methyl-1、3-pentadiene is reacted with ethyldiazoacetate in the presence of a copper catalyst and the resulting ethyl (+、-)- cis、trans-2、2-dimethyl-3-(2、2-dichlorovinyl)cyclopropanecarboxylate hydrolysed to the free acid. The cis- and trans-isomers can be separated from one another by selective crystallization from n-hexane in which the cis-isomer is more soluble. The starting acid is then reacted with 3-phenoxybenzyl alcohol to give permethrin.、Preparation of the racemic mixture: T. Mizutani et al、German patent 2437882 (1975 to Sumitomo)、F. Mori et al、German patent 2544150、eidem、United States of America patent 4113968 (1976、1978、both to Kuraray).、Formulations、Preparations: Dust、emulsifiable concentrate、smokes、ULV、ultra low volume、wettable powder.、Premix Partners: carboxin、dichlofluanid、piperonyl butoxide、tebuconazole、tetramethrin.、Technical material is a mixture of ~60% trans- and 40% cis-isomers.、Permethrin is typically a mixture of (+) cis and (+) trans esters ... in either a 40:60 or 25:75 ratio.、For more Formulations、Preparations (Complete) data for PERMETHRIN (46 total)、Consumption Patterns: In 1992、the estimated agricultural use of permethrin in the United States was about 1、055、097 pounds.、General Manufacturing Information: The WHO Recommended Classification of Pesticides by Hazard identifies permethrin (technical grade) as Class II: moderately hazardous、Main Use: insecticide.、Synthetic pyrethroid insecticide. ... Of the four possible isomers、the (1R、trans)- and the (1R、cis)-isomers are the two esters primarily responsible for insecticidal activity.、Permethrin was first registered and tolerances established in the United States in 1979 for use on cotton (April 29、1979 44FR 24287). The registration was made conditional due to the need for additional toxicology data to fully evaluate carcinogenicity and the need for additional ecological effects data to fully evaluate aquatic risk. Laboratory studies indicated that permethrin was highly toxic to fish and aquatic invertebrates and the use on cotton was classified as Restricted Use pesticide (RUP). In making its decision to conditionally register the product、EPA considered the beneficial role of this compound in cotton pest management、the reduction of use of other cotton insecticides with known carcinogenic potentials、and the absence of suitable and sufficient supplies of alternatives for control of resistant insect strains.、Permethrin is a restricted use pesticide for crop and wide area applications (i.e. nurseries、sod farms) due to high toxicity to aquatic organisms. It is a general use pesticide for residential and industrial applications.、For more General Manufacturing Information (Complete) data for PERMETHRIN (7 total)

应用领域

登记用途:Uses: Used as an ectoparasiticide in humans and animals、[Merck Index] Used as a nematocide、acaricide、and insecticide、[Hawley]、Farming (Pesticides) [Category: Industry]、For permethrin (USEPA、OPP Pesticide Code: 109701) ACTIVE products with label matches.、SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal、state and local authorities must be consulted for currently approved uses.、The pyrethroids are the most widely used class of insecticides in wood preservation because of their broad-spectrum activity、high efficacy especially against wood boring beetle、and high resistance to leaching.、Synthetic pyrethroids、Insecticide、seed treatment、protectant.、It has a potential application for forest protection and vector control for the control of noxious insects in the household and on cattle、for the control of body lice、and in mosquito nets.、For more Uses (Complete) data for PERMETHRIN (12 total)、please visit the HSDB record page.、Use (kg、approx.) in Germany (2009): >250、Consumption (g per capita、approx.) in Germany (2009): 0.00305、Calculated removal (%): 97.4、For the treatment of infestation with <i>Sarcoptes scabiei<、i> (scabies). Pyrethroids are used as insecticides. (L857)、Use Classification: Veterinary Drug -> INSECTICIDE -> JECFA Functional Classes、INSECTICIDES、Household Products: Cosmetics product ingredient: Permethrin (including cis- and trans-)、Source: Permethrin is a synthetic chemical used as a pesticide and insect repellent. It is used in agriculture、veterinary health、and medication. Permethrin may be added to lotions intended to treat scabies (a skin infection caused by mites)、and to sprays and shampoos used for lice control.、Potential health impacts: People may be exposed to permethrin by inhalation、ingestion、or through skin contact. Studies of scabies patients have found that dermal absorption of permethrin is low、but permethrin application may cause skin irritation. Inhaling permethrin may cause headache、nasal and respiratory irritation、dizziness、and nausea or vomiting. Studies of mice fed permethrin found increased rates of benign lung and liver tumors. The U.S. Environmental Protection Agency (U.S. EPA) classifies permethrin as likely to be carcinogenic to humans when ingested.、Product count: 2、Information on 256 consumer products that contain Permethrin in the following categories is provided:、• Commercial、Institutional、• Inside the Home、• Landscaping、Yard、• Personal Care、• Pesticides、• Pet Care、Methods of Manufacturing: Permethrin can be produced by condensation of 3-phenoxybenzyl alcohol with (1RS)-cis、trans-3-(2、2-dichlorovinyl)-2、2-dimethylcyclopropanecarboxylic acid.、The starting acid is prepared by a variation of the conventional chrysanthemic acid synthesis using ethyldiazoacetate in which 1、1-dichloro-4-methyl-1、3-pentadiene is reacted with ethyldiazoacetate in the presence of a copper catalyst and the resulting ethyl (+、-)- cis、trans-2、2-dimethyl-3-(2、2-dichlorovinyl)cyclopropanecarboxylate hydrolysed to the free acid. The cis- and trans-isomers can be separated from one another by selective crystallization from n-hexane in which the cis-isomer is more soluble. The starting acid is then reacted with 3-phenoxybenzyl alcohol to give permethrin.、Preparation of the racemic mixture: T. Mizutani et al、German patent 2437882 (1975 to Sumitomo)、F. Mori et al、German patent 2544150、eidem、United States of America patent 4113968 (1976、1978、both to Kuraray).、Formulations、Preparations: Dust、emulsifiable concentrate、smokes、ULV、ultra low volume、wettable powder.、Premix Partners: carboxin、dichlofluanid、piperonyl butoxide、tebuconazole、tetramethrin.、Technical material is a mixture of ~60% trans- and 40% cis-isomers.、Permethrin is typically a mixture of (+) cis and (+) trans esters ... in either a 40:60 or 25:75 ratio.、For more Formulations、Preparations (Complete) data for PERMETHRIN (46 total)、Consumption Patterns: In 1992、the estimated agricultural use of permethrin in the United States was about 1、055、097 pounds.、General Manufacturing Information: The WHO Recommended Classification of Pesticides by Hazard identifies permethrin (technical grade) as Class II: moderately hazardous、Main Use: insecticide.、Synthetic pyrethroid insecticide. ... Of the four possible isomers、the (1R、trans)- and the (1R、cis)-isomers are the two esters primarily responsible for insecticidal activity.、Permethrin was first registered and tolerances established in the United States in 1979 for use on cotton (April 29、1979 44FR 24287). The registration was made conditional due to the need for additional toxicology data to fully evaluate carcinogenicity and the need for additional ecological effects data to fully evaluate aquatic risk. Laboratory studies indicated that permethrin was highly toxic to fish and aquatic invertebrates and the use on cotton was classified as Restricted Use pesticide (RUP). In making its decision to conditionally register the product、EPA considered the beneficial role of this compound in cotton pest management、the reduction of use of other cotton insecticides with known carcinogenic potentials、and the absence of suitable and sufficient supplies of alternatives for control of resistant insect strains.、Permethrin is a restricted use pesticide for crop and wide area applications (i.e. nurseries、sod farms) due to high toxicity to aquatic organisms. It is a general use pesticide for residential and industrial applications.、For more General Manufacturing Information (Complete) data for PERMETHRIN (7 total)。

技术档案

这个产品是什么

氯菊酯 是一种化工化合物,登记 CAS 号为 93389-07-2,分子式 C21H20Cl2O3(分子量 391.3)。

识别信息

登记 CAS 号:93389-07-2

其分子式 C21H20Cl2O3 由 21 个碳、20 个氢、2 个氯、3 个氧 组成。

别名/同义词:氯菊酯 · Permethrin

常见问题

氯菊酯 的 CAS 号是多少?

氯菊酯 的 CAS 登记号为 93389-07-2。

氯菊酯 的分子式与分子量是多少?

分子式 C21H20Cl2O3,分子量 391.3。

氯菊酯 还有哪些别名?

别名/同义词:氯菊酯、Permethrin。

氯菊酯 的登记用途是什么?

登记用途:Uses: Used as an ectoparasiticide in humans and animals、[Merck Index] Used as a nematocide、acaricide、and insecticide、[Hawley]、Farming (Pesticides) [Category: Industry]、For permethrin (USEPA、OPP Pesticide Code: 109701) ACTIVE products with label matches.、SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal、state and local authorities must be consulted for currently approved uses.、The pyrethroids are the most widely used class of insecticides in wood preservation because of their broad-spectrum activity、high efficacy especially against wood boring beetle、and high resistance to leaching.、Synthetic pyrethroids、Insecticide、seed treatment、protectant.、It has a potential application for forest protection and vector control for the control of noxious insects in the household and on cattle、for the control of body lice、and in mosquito nets.、For more Uses (Complete) data for PERMETHRIN (12 total)、please visit the HSDB record page.、Use (kg、approx.) in Germany (2009): >250、Consumption (g per capita、approx.) in Germany (2009): 0.00305、Calculated removal (%): 97.4、For the treatment of infestation with <i>Sarcoptes scabiei<、i> (scabies). Pyrethroids are used as insecticides. (L857)、Use Classification: Veterinary Drug -> INSECTICIDE -> JECFA Functional Classes、INSECTICIDES、Household Products: Cosmetics product ingredient: Permethrin (including cis- and trans-)、Source: Permethrin is a synthetic chemical used as a pesticide and insect repellent. It is used in agriculture、veterinary health、and medication. Permethrin may be added to lotions intended to treat scabies (a skin infection caused by mites)、and to sprays and shampoos used for lice control.、Potential health impacts: People may be exposed to permethrin by inhalation、ingestion、or through skin contact. Studies of scabies patients have found that dermal absorption of permethrin is low、but permethrin application may cause skin irritation. Inhaling permethrin may cause headache、nasal and respiratory irritation、dizziness、and nausea or vomiting. Studies of mice fed permethrin found increased rates of benign lung and liver tumors. The U.S. Environmental Protection Agency (U.S. EPA) classifies permethrin as likely to be carcinogenic to humans when ingested.、Product count: 2、Information on 256 consumer products that contain Permethrin in the following categories is provided:、• Commercial、Institutional、• Inside the Home、• Landscaping、Yard、• Personal Care、• Pesticides、• Pet Care、Methods of Manufacturing: Permethrin can be produced by condensation of 3-phenoxybenzyl alcohol with (1RS)-cis、trans-3-(2、2-dichlorovinyl)-2、2-dimethylcyclopropanecarboxylic acid.、The starting acid is prepared by a variation of the conventional chrysanthemic acid synthesis using ethyldiazoacetate in which 1、1-dichloro-4-methyl-1、3-pentadiene is reacted with ethyldiazoacetate in the presence of a copper catalyst and the resulting ethyl (+、-)- cis、trans-2、2-dimethyl-3-(2、2-dichlorovinyl)cyclopropanecarboxylate hydrolysed to the free acid. The cis- and trans-isomers can be separated from one another by selective crystallization from n-hexane in which the cis-isomer is more soluble. The starting acid is then reacted with 3-phenoxybenzyl alcohol to give permethrin.、Preparation of the racemic mixture: T. Mizutani et al、German patent 2437882 (1975 to Sumitomo)、F. Mori et al、German patent 2544150、eidem、United States of America patent 4113968 (1976、1978、both to Kuraray).、Formulations、Preparations: Dust、emulsifiable concentrate、smokes、ULV、ultra low volume、wettable powder.、Premix Partners: carboxin、dichlofluanid、piperonyl butoxide、tebuconazole、tetramethrin.、Technical material is a mixture of ~60% trans- and 40% cis-isomers.、Permethrin is typically a mixture of (+) cis and (+) trans esters ... in either a 40:60 or 25:75 ratio.、For more Formulations、Preparations (Complete) data for PERMETHRIN (46 total)、Consumption Patterns: In 1992、the estimated agricultural use of permethrin in the United States was about 1、055、097 pounds.、General Manufacturing Information: The WHO Recommended Classification of Pesticides by Hazard identifies permethrin (technical grade) as Class II: moderately hazardous、Main Use: insecticide.、Synthetic pyrethroid insecticide. ... Of the four possible isomers、the (1R、trans)- and the (1R、cis)-isomers are the two esters primarily responsible for insecticidal activity.、Permethrin was first registered and tolerances established in the United States in 1979 for use on cotton (April 29、1979 44FR 24287). The registration was made conditional due to the need for additional toxicology data to fully evaluate carcinogenicity and the need for additional ecological effects data to fully evaluate aquatic risk. Laboratory studies indicated that permethrin was highly toxic to fish and aquatic invertebrates and the use on cotton was classified as Restricted Use pesticide (RUP). In making its decision to conditionally register the product、EPA considered the beneficial role of this compound in cotton pest management、the reduction of use of other cotton insecticides with known carcinogenic potentials、and the absence of suitable and sufficient supplies of alternatives for control of resistant insect strains.、Permethrin is a restricted use pesticide for crop and wide area applications (i.e. nurseries、sod farms) due to high toxicity to aquatic organisms. It is a general use pesticide for residential and industrial applications.、For more General Manufacturing Information (Complete) data for PERMETHRIN (7 total)。

PubChem 公开数据

氯菊酯(CAS 93389-07-2)的独立参考数据,整理自公开化学数据库。

各数据库的登记标识

CAS Registry Number93389-07-2
PubChem CID40326
Molecular formulaC21H20Cl2O3
IUPAC name(3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate

计算分子描述符

Molecular Weight391.3
XLogP36.5
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count7
Exact Mass390.0789499
Monoisotopic Mass390.0789499
Topological Polar Surface Area35.5
Heavy Atom Count26

在册的理化数值

Boiling Point220
Boiling Point>290 °C at 760 mm Hg
Boiling PointBP: 200 °C at 0.1 mm Hg
Melting Point34
Melting Point<20 °C (OECD Method 102)
Melting Point34 °C
Melting Point34-39 °C
Solubility0.006
SolubilityIn water, 6.00X10-3 mg/ml @ 20 °C.
Solubility6.91e-05 g/L

在册的记载用途

    Used as an ectoparasiticide in humans and animals; [Merck Index] Used as a nematocide, acaricide, and insecticide; [Hawley]The pyrethroids are the most widely used class of insecticides in wood preservation because of their broad-spectrum activity, high efficacy especially against wood boring beetle, and high resistance to leaching. /Synthetic pyrethroids/

    同义词与商品名

    Permethrin; 52645-53-1; Pounce; Permethrine; Permetrina; Elimite; Kudos; (3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate; Permethrinum; Acticin; Ambushfog; Chinetrin; Corsair; Dragnet; Ecsumin; Ectiban

    已收录的法规名录

    Regulatory & Food ContactINSECTICIDE: Veterinary Drug
    Not established
    TRS 900-JECFA 54/52
    GHS notification summary0.2% (1 / 519)

    GHS 危害分类

    GHS notification summary0.2% (1 / 519)
    Reported hazard statementsH302, H317, H332, H400, H410, H351, H370, H373

    H302: Harmful if swallowed [Warning Acute toxicity, oral]

    H317: May cause an allergic skin reaction [Warning Sensitization, Skin]

    公开数据库对它的描述

    Permethrin · CAS 93389-07-2 · C21H20Cl2O3. Boiling Point: 220; Boiling Point: >290 °C at 760 mm Hg; Boiling Point: BP: 200 °C at 0.1 mm Hg.

    物理形态与操作说明

    数据来源:PubChem / Wikidata;与随货 COA 不一致时以 COA 为准。

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