布雷菲德菌素A

Description

Brefeldin A · CAS 20350-15-6 · C16H24O4. UNII XG0D35F9K6.

Identification

CAS Registry Number	20350-15-6
PubChem CID	5287620
Molecular formula	C16H24O4
IUPAC name	(1R,2R,3E,7S,11E,13S,15S)-2,15-dihydroxy-7-methyl-6-oxabicyclo[11.3.0]hexadeca-3,11-dien-5-one
UNII (FDA)	XG0D35F9K6

Computed Descriptors

Molecular Weight	280.36
XLogP3	2
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	0
Exact Mass	280.16745924
Monoisotopic Mass	280.16745924
Topological Polar Surface Area	66.8
Heavy Atom Count	20
Formal Charge	0

GHS Hazard Classification

Reported hazard statements	H301 (97.3%)

Documented Uses

• Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues.
• Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.
• Compounds which inhibit the synthesis of proteins. They are usually ANTI-BACTERIAL AGENTS or toxins. Mechanism of the action of inhibition includes the interruption of peptide-chain elongation, the blocking the A site of ribosomes, the misreading of the genetic code or the prevention of the attachment of oligosaccharide side chains to glycoproteins.
• Substances that inhibit the growth or reproduction of BACTERIA.

Synonyms

brefeldin A; Ascotoxin; Decumbin; Cyanein; 20350-15-6; Synergisidin; Nectrolide; (+)-Brefeldin A; NSC-89671; NSC-56310; NSC-107456; NSC-244390; XG0D35F9K6; DTXSID00880041; NSC 89671; CHEBI:48080

Frequently Asked Questions

What are the CAS number and molecular formula of Brefeldin A?

CAS 20350-15-6; molecular formula C16H24O4; molecular weight — g/mol.

What other names is Brefeldin A known by?

brefeldin A, Ascotoxin, Decumbin, Cyanein, 20350-15-6, Synergisidin.

Is Brefeldin A classified as hazardous?

Hazard statements reported: H301.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.