4-氨基苯甲酸

Description

4-Aminobenzoic acid · CAS 150-13-0 · C7H7NO2. UNII TL2TJE8QTX. Melting Point: 370 to 372 °F (NTP, 1992); Melting Point: 188.5; Melting Point: 188.5 °C.

Identification

CAS Registry Number	150-13-0
PubChem CID	978
Molecular formula	C7H7NO2
IUPAC name	4-aminobenzoic acid
UNII (FDA)	TL2TJE8QTX

Computed Descriptors

Molecular Weight	137.14
XLogP3	0.8
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	1
Exact Mass	137.047678466
Monoisotopic Mass	137.047678466
Topological Polar Surface Area	63.3
Heavy Atom Count	10
Formal Charge	0

Physical & Chemical Properties

Melting Point	370 to 372 °F (NTP, 1992)
Melting Point	188.5
Melting Point	188.5 °C
Melting Point	188 °C
Solubility	6110
Solubility	6.11 mg/mL
Vapor Pressure	0.000278 [mmHg]
LogP	0.83
LogP	log Kow = 0.83
pH	pH (0.5% solution): 3.5

Physical description & handling notes

• P-aminobenzoic acid appears as colorless crystals that discolor on exposure to light and air. (NTP, 1992)
• Light beige, odorless solid; pure form is white; discolor on exposure to light and air; [Hawley] White crystalline solid; [MSDSonline]
• Solid
• Monoclinic prisms from dilute alcohol
• Light buff crystals; white when pure
• Yellowish to red crystals or prisms

Regulatory Status

Regulatory & Food Contact	FDA Substance added to food: NUTRIENT SUPPLEMENT CIR / INCI: Uv absorber; Uv filter
GHS notification summary	21.9% (53 / 242)

GHS Hazard Classification

GHS notification summary	21.9% (53 / 242)
Reported hazard statements	H315 (32.2%), H317 (27.7%), H319 (33.1%), H335 (32.2%), H412 (44.6%)

Documented Uses

• Used to make local anesthetics, folic acid, and azo dyes; Also used in feed additives, sunscreens, and medications; [HSDB] Occurs naturally as B complex factor--about 10-100 ppm in brewer's yeast;
• Farming (Feed Additives) [Category: Industry]
• Manufacture /of/ various esters (local anesthetics), folic acid, and azo dyes; ... . Used in laboratories as sulfonamide antagonist.
• Dye intermediate, pharmaceuticals, nutrition, UV absorber in suntan lotions.
• Used principally in the pharmaceuticals industry; other uses are as a cross-linking agent for polyurethane resins, dyes, and feedstock additives.
• Use (kg; approx.) in Germany (2009): >2500

Synonyms

4-aminobenzoic acid; 150-13-0; p-aminobenzoic acid; PABA; Vitamin BX; p-Carboxyaniline; para-aminobenzoic acid; Sunbrella; 4-Carboxyaniline; Paraminol; Pabacyd; Amben; Benzoic acid, 4-amino-; p-Carboxyphenylamine; Pabafilm; Pabamine

Frequently Asked Questions

What are the CAS number and molecular formula of 4-Aminobenzoic acid?

CAS 150-13-0; molecular formula C7H7NO2; molecular weight — g/mol.

What other names is 4-Aminobenzoic acid known by?

4-aminobenzoic acid, 150-13-0, p-aminobenzoic acid, PABA, Vitamin BX, p-Carboxyaniline.

What is the regulatory status of 4-Aminobenzoic acid?

Documented regulatory listings: FDA Substance added to food: NUTRIENT SUPPLEMENT; CIR / INCI: Uv absorber; Uv filter.

Is 4-Aminobenzoic acid classified as hazardous?

21.9% of GHS notifications report no hazard classification (53 of 242).

What are the key physical properties of 4-Aminobenzoic acid?

Melting Point: 370 to 372 °F (NTP, 1992); Melting Point: 188.5; Melting Point: 188.5 °C; Melting Point: 188 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.