HC蓝2（CAS 33229-34-4）：分子式 C12H19N3O5、分子量 285.30。
| CAS号 | 33229-34-4 |
|---|---|
| 分子式 | C12H19N3O5 |
| 分子量 | 285.30 |
| 熔点 | 182 to 194 °F (NTP, 1992) |
| LogP | Log P= 1.7 |
| 应用领域 | Uses: CIR ingredient: HC Blue No. 2、Used as a dye in semi-permanent hair dye formulations、Not commercially produced in the US、[HSDB]、Dressing Hair [Category: Other]、HC Blue #2 is used exclusively as a dye in semi-permanent hair coloring products. The concentration of HC Blue #2 used in these preparations ranges from 1.6-2%.、Use Classification: Cosmetics -> Hair dyeing、Household Products: Information on 15 consumer products that contain HC Blue No 2 in the following categories is provided:、• Personal Care、Methods of Manufacturing: HC Blue #2 that is greater than or equal to 95% pure is produced commercially by the reaction of 4-fluoro-3-nitrobenzenamine with ethylene oxide to form 2、2-(4-fluoro-3-nitrophenyl)imino)bis(ethanol)、this intermediate is reacted with monoethanolamine to form HC Blue #2.、The technical grade is produced by reaction of 2-nitro-p-phenylenediamine with ethylene oxide or 2-chloroethanol.、Impurities: HC Blue #2 is available commercially with a purity greater than or equal to 95% with possible impurities、including methylamine (<1%)、1、2-dihydroxyethane (<1%)、and water (<1%). It is also available in a technical grade containing 55-90% dye、10-30% inorganic salts and 2、2-((4-amino-3-nitrophenyl)imino)bis (ethanol) (<7%) as a possible impurity.、U.S. Production: (1977) NOT PRODUCED COMMERCIALLY IN US、(1979) NOT PRODUCED COMMERCIALLY IN US、General Manufacturing Information: Production and use of HC Blue #2 began in the late 1950s. Approximately 9-11 tons are used annually in the USA、according to industry estimates. |
登记用途：Uses: CIR ingredient: HC Blue No. 2、Used as a dye in semi-permanent hair dye formulations、Not commercially produced in the US、[HSDB]、Dressing Hair [Category: Other]、HC Blue #2 is used exclusively as a dye in semi-permanent hair coloring products. The concentration of HC Blue #2 used in these preparations ranges from 1.6-2%.、Use Classification: Cosmetics -> Hair dyeing、Household Products: Information on 15 consumer products that contain HC Blue No 2 in the following categories is provided:、• Personal Care、Methods of Manufacturing: HC Blue #2 that is greater than or equal to 95% pure is produced commercially by the reaction of 4-fluoro-3-nitrobenzenamine with ethylene oxide to form 2、2-(4-fluoro-3-nitrophenyl)imino)bis(ethanol)、this intermediate is reacted with monoethanolamine to form HC Blue #2.、The technical grade is produced by reaction of 2-nitro-p-phenylenediamine with ethylene oxide or 2-chloroethanol.、Impurities: HC Blue #2 is available commercially with a purity greater than or equal to 95% with possible impurities、including methylamine (<1%)、1、2-dihydroxyethane (<1%)、and water (<1%). It is also available in a technical grade containing 55-90% dye、10-30% inorganic salts and 2、2-((4-amino-3-nitrophenyl)imino)bis (ethanol) (<7%) as a possible impurity.、U.S. Production: (1977) NOT PRODUCED COMMERCIALLY IN US、(1979) NOT PRODUCED COMMERCIALLY IN US、General Manufacturing Information: Production and use of HC Blue #2 began in the late 1950s. Approximately 9-11 tons are used annually in the USA、according to industry estimates.。
HC蓝2 是一种化工化合物，登记 CAS 号为 33229-34-4，分子式 C12H19N3O5（分子量 285.30）。
登记 CAS 号：33229-34-4
其分子式 C12H19N3O5 由 12 个碳、19 个氢、3 个氮、5 个氧 组成。
别名/同义词：HC蓝2 · HC Blue 2 · 2,2'-(4-(2-hydroxyethylamino)-3-nitro-phenylimino)
HC蓝2 的 CAS 登记号为 33229-34-4。
分子式 C12H19N3O5，分子量 285.30。
别名/同义词：HC蓝2、HC Blue 2、2,2'-(4-(2-hydroxyethylamino)-3-nitro-phenylimino)。
登记用途：Uses: CIR ingredient: HC Blue No. 2、Used as a dye in semi-permanent hair dye formulations、Not commercially produced in the US、[HSDB]、Dressing Hair [Category: Other]、HC Blue #2 is used exclusively as a dye in semi-permanent hair coloring products. The concentration of HC Blue #2 used in these preparations ranges from 1.6-2%.、Use Classification: Cosmetics -> Hair dyeing、Household Products: Information on 15 consumer products that contain HC Blue No 2 in the following categories is provided:、• Personal Care、Methods of Manufacturing: HC Blue #2 that is greater than or equal to 95% pure is produced commercially by the reaction of 4-fluoro-3-nitrobenzenamine with ethylene oxide to form 2、2-(4-fluoro-3-nitrophenyl)imino)bis(ethanol)、this intermediate is reacted with monoethanolamine to form HC Blue #2.、The technical grade is produced by reaction of 2-nitro-p-phenylenediamine with ethylene oxide or 2-chloroethanol.、Impurities: HC Blue #2 is available commercially with a purity greater than or equal to 95% with possible impurities、including methylamine (<1%)、1、2-dihydroxyethane (<1%)、and water (<1%). It is also available in a technical grade containing 55-90% dye、10-30% inorganic salts and 2、2-((4-amino-3-nitrophenyl)imino)bis (ethanol) (<7%) as a possible impurity.、U.S. Production: (1977) NOT PRODUCED COMMERCIALLY IN US、(1979) NOT PRODUCED COMMERCIALLY IN US、General Manufacturing Information: Production and use of HC Blue #2 began in the late 1950s. Approximately 9-11 tons are used annually in the USA、according to industry estimates.。
HC蓝2（CAS 33229-34-4）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 33229-34-4 |
|---|---|
| PubChem CID | 36383 |
| Molecular formula | C12H19N3O5 |
| IUPAC name | 2-[4-[bis(2-hydroxyethyl)amino]-2-nitroanilino]ethanol |
| UNII (FDA) | 6C0EL1931V |
| Molecular Weight | 285.30 |
|---|---|
| XLogP3 | 0.4 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 8 |
| Exact Mass | 285.13247072 |
| Monoisotopic Mass | 285.13247072 |
| Topological Polar Surface Area | 122 |
| Heavy Atom Count | 20 |
| Melting Point | 182 to 194 °F (NTP, 1992) |
|---|---|
| Melting Point | 93-98 °C (98% pure) |
| LogP | Log P= 1.7 |
33229-34-4; HC Blue no. 2; HC Blue 2; DTXSID6020193; NCI-C54897; 6C0EL1931V; Ethanol, 2,2'-((4-((2-hydroxyethyl)amino)-3-nitrophenyl)imino)di-; DTXCID80193; N1,N4,N4-Tris(2-hydroxyethyl)-2-nitro-p-phenylenediamine; COVARINE BLUE W 6122; p-Phenylenediamine, 3-nitro-N(sup 1),N(sup 1),N(sup 4)-tris(2-hydroxyethyl)-; RefChem:145365; 251-410-3; 2,2'-[4-(2-Hydroxyethylamino)-3-nitrophenylimino]diethanol; 2,2'-((4-((2-Hydroxyethyl)amino)-3-nitrophenyl)azanediyl)diethanol; 2-[4-[bis(2-hydroxyethyl)amino]-2-nitroanilino]ethanol
| Regulatory & Food Contact | CIR / INCI: Cosmetic ingredients (HC Blue No. 2) -> CIR (Cosmetic Ingredient Review) CIR / INCI: Hair dyeing |
|---|---|
| GHS notification summary | 0.9% (1 / 116) |
| GHS notification summary | 0.9% (1 / 116) |
|---|---|
| Reported hazard statements | H315 (50%), H317 (40.5%), H319 (50%), H335 (49.1%), H412 (18.1%) |
This chemical does not meet GHS hazard criteria for 0.9% (1 of 116) of reports.
H315 (50%): Causes skin irritation [Warning Skin corrosion/irritation]
2,2'-(4-(2-hydroxyethylamino)-3-nitro-phenylimino) · CAS 33229-34-4 · C12H19N3O5. UNII 6C0EL1931V. Melting Point: 182 to 194 °F (NTP, 1992); Melting Point: 93-98 °C (98% pure); LogP: Log P= 1.7.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: HC Blue 2