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Alprostadil

CAS 745-65-3C20H34O5MW 354.5

Alprostadil (CAS 745-65-3) — formula C20H34O5, molecular weight 354.5; category pharmaceutical intermediates and APIs.

Product Description

Alprostadil (CAS 745-65-3) is a chemical raw material in the pharmaceutical intermediates and APIs category. Its molecular formula C20H34O5 comprises 20 C, 34 H, 5 O atoms. Its molecular weight is about 354.5. Reported physicochemical data: melting point around 115-116 °C, LogP about 3.2. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.

Product Overview

CAS Number745-65-3
Molecular FormulaC20H34O5
Molecular Weight354.5
Melting Point115-116 °C
LogP3.2
CategoryPharmaceutical Intermediates & APIs

Technical Profile

What this product is

Alprostadil is a pharmaceutical intermediate or API compound with CAS registry number 745-65-3 and molecular formula C20H34O5 (molecular weight 354.5), belonging to the pharmaceutical intermediates and APIs segment of chemical raw materials.

Identification

CAS number: 745-65-3

Its molecular formula C20H34O5 comprises 20 C, 34 H, 5 O atoms.

Also known as: Alprostadil · 前列地尔

Category: pharmaceutical intermediates and APIs

Frequently Asked Questions

What is the CAS number of Alprostadil?

The CAS registry number of Alprostadil is 745-65-3.

What is the molecular formula and molecular weight of Alprostadil?

Molecular formula C20H34O5, molecular weight 354.5.

What other names is Alprostadil known by?

It is also registered under: Alprostadil, 前列地尔.

Which category does Alprostadil belong to?

Category: Pharmaceutical Intermediates & APIs.

Packaging & documentation

Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.

PubChem Public Data

Independent reference data for Alprostadil (CAS 745-65-3), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number745-65-3
PubChem CID5280723
Molecular formulaC20H34O5
IUPAC name7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid
UNII (FDA)F5TD010360

Computed descriptors

Molecular Weight354.5
XLogP33.2
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count13
Exact Mass354.24062418
Monoisotopic Mass354.24062418
Topological Polar Surface Area94.8
Heavy Atom Count25

Physicochemical values on record

Melting Point115-116 °C
Melting Point115 - 116 °C
Solubility26.7
LogP3.2
LogP3.20
Dissociation Constants4.87
Dissociation Constants4.85 (at 25 °C)

Documented uses on record

    Alprostadil is indicated for palliative, not definitive, therapy to temporarily maintain the patency of the ductus arteriosus until corrective or palliative surgery can be performed in neonates who have congenital heart defects and who depend upon the patent ductus for survival. It is also indicated for the treatment of erectile dysfunction due to neurogenic, vasculogenic, psychogenic, or mixed etiology, and as an adjunct to other diagnostic tests in the diagnosis of erectile dysfunction.Medicines administered to the neonate [c]

    Synonyms and trade names

    alprostadil; Prostaglandin E1; 745-65-3; PGE1; Caverject; Edex; Muse; Alprostadilum; Befar; Prostin VR Pediatric; Vitaros; Prink; PGE-1; Prostavasin; (11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid; Caverject Impulse

    GHS hazard classification

    Reported hazard statementsH301 (100%), H361 (56.8%)

    H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]

    H361 (56.8%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

    What the public record says

    Alprostadil · CAS 745-65-3 · C20H34O5. UNII F5TD010360. Melting Point: 115-116 °C; Melting Point: 115 - 116 °C; Solubility: 26.7.

    Source: PubChem / Wikidata; the batch COA governs where values differ.

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Supplier: Jinan Shenghe Chemical Co., Ltd.

中文页面: 前列地尔

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