Levetiracetam

Description

Levetiracetam · CAS 102767-28-2 · C8H14N2O2. UNII 44YRR34555. Melting Point: 115-119C; Melting Point: 117 °C; Solubility: 104g/100mL.

Identification

CAS Registry Number	102767-28-2
PubChem CID	5284583
Molecular formula	C8H14N2O2
IUPAC name	(2S)-2-(2-oxopyrrolidin-1-yl)butanamide
UNII (FDA)	44YRR34555

Computed Descriptors

Molecular Weight	170.21
XLogP3	-0.3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	3
Exact Mass	170.105527694
Monoisotopic Mass	170.105527694
Topological Polar Surface Area	63.4
Heavy Atom Count	12
Formal Charge	0

Physical & Chemical Properties

Melting Point	115-119C
Melting Point	117 °C
Solubility	104g/100mL
Vapor Pressure	3.5X10-6 mm Hg at 25 °C
LogP	-0.6
LogP	-0.65

Physical description & handling notes

• Crystals from ethyl acetate
• White to off-white crystalline powder
• Faint
• Bitter
• Very soluble in water (104.0 g/100 mL). It is freely soluble in chloroform (65.3 g/100 mL) and in methanol (53.6 g/mL), soluble in ethanol (16.5 g/mL), sparingly soluble in acetonitrile (5.7 g/100 mL) and practically insoluble in n-hexane. (Solubility limits are expressed as g/100 mL solvent)
• Specific optical rotation: -90 deg at 25 °C/D (c = 1 in acetone)

Regulatory Status

GHS notification summary	1.7% (2 / 119)

GHS Hazard Classification

GHS notification summary	1.7% (2 / 119)
Reported hazard statements	H302 (89.1%), H319 (89.1%)

Documented Uses

• Use (kg) in Switzerland (2009): >2500
• Use (kg; approx.) in Germany (2009): >50000
• Use (kg; exact) in Germany (2009): 53353
• Consumption (g per capita) in Switzerland (2009): 0.32
• Consumption (g per capita; approx.) in Germany (2009): 0.61
• Consumption (g per capita; exact) in Germany (2009): 0.65

Synonyms

Levetiracetam; 102767-28-2; Keppra; (2S)-2-(2-oxopyrrolidin-1-yl)butanamide; Keppra XR; Spritam; UCB-L 059; ucb L059; matever; Levetiracetame; Levetiracetamum; Levetiracetam teva; UCB-L059; Elepsia; (S)-alpha-Ethyl-2-oxo-1-pyrrolidineacetamide; Levetiracetam sun

Frequently Asked Questions

What are the CAS number and molecular formula of Levetiracetam?

CAS 102767-28-2; molecular formula C8H14N2O2; molecular weight — g/mol.

What other names is Levetiracetam known by?

Levetiracetam, 102767-28-2, Keppra, (2S)-2-(2-oxopyrrolidin-1-yl)butanamide, Keppra XR, Spritam.

Is Levetiracetam classified as hazardous?

1.7% of GHS notifications report no hazard classification (2 of 119).

What are the key physical properties of Levetiracetam?

Melting Point: 115-119C; Melting Point: 117 °C; Solubility: 104g/100mL; Vapor Pressure: 3.5X10-6 mm Hg at 25 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.