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甲氧虫酰肼

CAS 161050-58-4C22H28N2O3MW 368.5

济南圣和化工主营供应 甲氧虫酰肼(CAS 161050-58-4),归类于医药中间体及原料药,分子式 C22H28N2O3,分子量 368.5。我们面向国内化工贸易与生产企业提供稳定的现货供应,报价响应快,支持对公转账并可开具增值税发票。

产品概览

CAS号161050-58-4
分子式C22H28N2O3
分子量368.5
熔点206.2 - 208 °C
LogP4.6
纯度按批次COA提供(不公开发布)
包装按订单/批次确认(不公开发布)
应用领域医药中间体及原料药
类别医药中间体及原料药

应用领域

医药中间体及原料药

甲氧虫酰肼在医药中间体及原料药领域使用广泛。采购前请确认纯度等级与包装形式,以批次 COA 为验收依据。

包装与储存

包装规格按订单/批次确认(不公开发布)
纯度规格按批次COA提供(不公开发布)
储存条件密封、阴凉干燥处保存
运输常规化工运输
样品可协商提供
交期现货/按订单安排

供应说明:甲氧虫酰肼 常规包装为按订单/批次确认(不公开发布),储存时应密封置于阴凉干燥处,避免与氧化剂混放。济南圣和化工有限公司 支持国内物流发货,大货交期与运费以订单确认为准。

质量与文件

每批产品随货提供 COA(分析证书);可按需提供 MSDS/技术数据表及第三方检测报告。纯度与包装以批次 COA 及订单确认为准。

关于供应商

作为化工原料供应服务商,济南圣和化工有限公司 长期服务于化工贸易、食品添加、医药中间体、日化原料等行业的采购需求。除 甲氧虫酰肼 外,您还可以在站内按 CAS 号或产品分类检索更多品类,获取规格与报价。

常见问题

甲氧虫酰肼 的 CAS 号是多少?

甲氧虫酰肼 的 CAS 号为 161050-58-4。

该产品的纯度和包装规格是什么?

常规纯度规格为 按批次COA提供(不公开发布),包装为 按订单/批次确认(不公开发布),随货提供 COA。

甲氧虫酰肼 有什么用途?

主要应用于医药中间体及原料药。

如何购买或获取报价?

请发送邮件至 info@591daili.com 或通过 WhatsApp 联系,注明产品名称、CAS 号与需求数量,一个工作日内回复报价。供应商:济南圣和化工有限公司。

PubChem 公开数据

Description

Methoxyfenozide · CAS 161050-58-4 · C22H28N2O3. UNII 62A22651ZX. Melting Point: 206.2 - 208 °C; Melting Point: MP: 204 - 20.6 °C /Technical/; Solubility: In water, 3.3 mg/L at 20 °C.

Identification

CAS Registry Number161050-58-4
PubChem CID105010
Molecular formulaC22H28N2O3
IUPAC nameN'-tert-butyl-N'-(3,5-dimethylbenzoyl)-3-methoxy-2-methylbenzohydrazide
UNII (FDA)62A22651ZX

Computed Descriptors

Molecular Weight368.5
XLogP34.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Exact Mass368.20999276
Monoisotopic Mass368.20999276
Topological Polar Surface Area58.6
Heavy Atom Count27
Formal Charge0

Physical & Chemical Properties

Melting Point206.2 - 208 °C
Melting PointMP: 204 - 20.6 °C /Technical/
SolubilityIn water, 3.3 mg/L at 20 °C

Physical description & handling notes

  • White powder
  • In DMSO 11, cyclohexanone 9.9, acetone 9 (all in g/100g at 20 °C)
  • log Kow = 3.7 (shake flask)
  • When heated to decomposition it emits toxic vapors of /nitrogen oxides/.
  • 201.9 Ų [M+Na]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID3032628]
  • 194.2 Ų [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: TOXCAST; Source Identifier: DTXSID3032628]

GHS Hazard Classification

Reported hazard statementsH400 (69.9%), H410 (69.9%), H411 (30.1%), H401

H400 (69.9%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]

H410 (69.9%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

Documented Uses

  • The dermal absorption in vivo of methoxyfenozide formulated as an aqueous flow-able liquid (RH-112,485 2F) or as a wettable powder (RH-112,485 280WP) was tested in rats in a study that was designed to comply with US EPA guidelines and GLP. The methoxyfenozide administered was uniformly labelled with (14)C on the methoxyphenyl ring; this is acceptable given the limited cleavage seen in studies of oral metabolism. To provide data on exposure to the concentrated product and in-use-dilutions, groups of four male Crl :
  • Two metabolites, M16 (A-ring glucuronide of M14) and M26 (A-ring glucuronide of M24), were the main metabolites in bile. M16 was present at 13% and 18% in males and females respectively, M26 was present at 5% in males and 11% in females, all other metabolites represented <3% of the administered dose. The presence of M16 and M26 at higher concentrations in bile than in feces indicates that these two metabolites were subject to subsequent hydrolysis.
  • The primary /metabolic/ pathway probably involves demethylation of the A-ring methoxy moiety to form the corresponding phenol (M14), which is conjugated with glucuronic acid to form M16. Hydroxylation on the B-ring methyl moieties is also a significant metabolic pathway. Cleavage of methoxyfenozide to release either of the rings or the t-butyl group is only a minor pathway; none of the cleaved metabolites (M06, M07, M13, M32-36) were present at >2% of the dose. In males, however, cleaved metabolites represented up
  • Results for the animals receiving diets containing methoxyfenozide for 14 days plus a single dose of (14C) methoxyfenozide at 10 mg/kg bw by gavage showed evidence of induction of metabolism. Concentrations of M22, M28 and M30 increased, while concentrations of M14 and M24 were reduced relative to concentrations in animals that received only a single dose of (14C) methoxyfenozide at 10 mg/kg bw.

Synonyms

Methoxyfenozide; 161050-58-4; Intrepid; N'-tert-Butyl-N'-(3,5-dimethylbenzoyl)-3-methoxy-2-methylbenzohydrazide; Runner; 3-Methoxy-2-methylbenzoic acid 2-(3,5-dimethylbenzoyl)-2-(1,1-dimethylethyl)hydrazide; Benzoic acid, 3-methoxy-2-methyl-, 2-(3,5-dimethylbenzoyl)-2-(1,1-dimethylethyl)hydrazide; RH-2485; DTXSID3032628; N'-(tert-butyl)-N'-(3,5-dimethylbenzoyl)-3-methoxy-2-methylbenzohydrazide; N-tert-butyl-N'-(3-methoxy-o-toluoyl)-3,5-xylohydrazide; 62A22651ZX; DTXCID1012628; CHEBI:38449; RH-112485; RefChem:157081

Frequently Asked Questions

What are the CAS number and molecular formula of Methoxyfenozide?

CAS 161050-58-4; molecular formula C22H28N2O3; molecular weight — g/mol.

What other names is Methoxyfenozide known by?

Methoxyfenozide, 161050-58-4, Intrepid, N'-tert-Butyl-N'-(3,5-dimethylbenzoyl)-3-methoxy-2-methylbenzohydrazide, Runner, 3-Methoxy-2-methylbenzoic acid 2-(3,5-dimethylbenzoyl)-2-(1,1-dimethylethyl)hydrazide.

Is Methoxyfenozide classified as hazardous?

Hazard statements reported: H400, H410, H411, H401.

What are the key physical properties of Methoxyfenozide?

Melting Point: 206.2 - 208 °C; Melting Point: MP: 204 - 20.6 °C /Technical/; Solubility: In water, 3.3 mg/L at 20 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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English page: Methoxyfenozide

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