肌酐

Description

Creatinine · CAS 60-27-5 · C4H7N3O. UNII AYI8EX34EU. Melting Point: 303 °C (decomposes); Solubility: 80.1 mg/mL at 16 °C; Vapor Pressure: 0.000217 [mmHg].

Identification

CAS Registry Number	60-27-5
PubChem CID	588
Molecular formula	C4H7N3O
IUPAC name	2-amino-3-methyl-4H-imidazol-5-one
UNII (FDA)	AYI8EX34EU

Computed Descriptors

Molecular Weight	113.12
XLogP3	-1.8
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	0
Exact Mass	113.058911855
Monoisotopic Mass	113.058911855
Topological Polar Surface Area	58.7
Heavy Atom Count	8
Formal Charge	0

Physical & Chemical Properties

Melting Point	303 °C (decomposes)
Solubility	80.1 mg/mL at 16 °C
Vapor Pressure	0.000217 [mmHg]
LogP	-1.76
Collision Cross Section	123.4 Ų [M+H]+
Collision Cross Section	123.3 Ų [M+H]+
Collision Cross Section	132.8 Ų [M+Na]+
Collision Cross Section	132.9 Ų [M+Na]+
Collision Cross Section	119.8 Ų [M-H]-
Collision Cross Section	119.1 Ų [M-H]-

Physical description & handling notes

• Solid; [Merck Index] White crystalline powder; [Alfa Aesar MSDS]
• Solid

Regulatory Status

Regulatory & Food Contact	CIR / INCI: Skin conditioning
GHS notification summary	60% (6 / 10)

GHS Hazard Classification

GHS notification summary	60% (6 / 10)
Reported hazard statements	H315 (40%), H319 (40%), H335 (40%), H336 (10%)

Documented Uses

• Used as a bulking agent for freeze drying; [ChemIDplus] Final metabolic product of creatine that is found in all bodily fluids; Used in determination of renal function; [Merck Index]
• 4H-Imidazol-4-one, 2-amino-1,5-dihydro-1-methyl-: ACTIVE

Synonyms

2-Imino-1-methylimidazolidin-4-one; 1-Methylglycocyamidine; 1-Methylhydantoin-2-imide; Kreatinin; Creatinine,heated; Kreatininum; 2-amino-1-methylimidazolin-4-one; 2-amino-3-methyl-4H-imidazol-5-one; 2-amino-1-methyl-1,5-dihydro-4H-imidazol-4-one; 4H-Imidazol-4-one, 2-amino-1,5-dihydro-1-methyl-; creatinina; NSC-13123; AYI8EX34EU; 2-Amino-1,5-dihydro-1-methyl-4H-imidazol-4-one; CHEMBL65567; CHEBI:16737

Frequently Asked Questions

What are the CAS number and molecular formula of Creatinine?

CAS 60-27-5; molecular formula C4H7N3O; molecular weight — g/mol.

What other names is Creatinine known by?

2-Imino-1-methylimidazolidin-4-one, 1-Methylglycocyamidine, 1-Methylhydantoin-2-imide, Kreatinin, Creatinine,heated, Kreatininum.

What is the regulatory status of Creatinine?

Documented regulatory listings: CIR / INCI: Skin conditioning.

Is Creatinine classified as hazardous?

60% of GHS notifications report no hazard classification (6 of 10).

What are the key physical properties of Creatinine?

Melting Point: 303 °C (decomposes); Solubility: 80.1 mg/mL at 16 °C; Vapor Pressure: 0.000217 [mmHg]; LogP: -1.76.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.