磷酸氯喹

Description

Chloroquine Phosphate · CAS 50-63-5 · C18H32ClN3O8P2. UNII 6E17K3343P.

Identification

Computed Descriptors

Physical description & handling notes

• 175.6 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

Documented Uses

• For the suppressive treatment and for acute attacks of malaria due to P. vivax, P.malariae, P. ovale, and susceptible strains of P. falciparum, Second-line agent in treatment of Rheumatoid Arthritis (A308).
• Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
• Information on 1 consumer products that contain Chloroquine phosphate in the following categories is provided:
• Breast Feeding; Lactation; Milk, Human; Anti-infective Agents; Antiparasitic Agents; Antimalarials; Antirheumatic Agents; Antiprotozoal Agents
• Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
• Agents used in the treatment of malaria. They are usually classified on the basis of their action against plasmodia at different stages in their life cycle in the human. (From AMA, Drug Evaluations Annual, 1992, p1585)

Synonyms

Chloroquine diphosphate; Chloroquine phosphate; Aralen phosphate; Resochin; Arechin; Avloclor; Delagil; Chingamin phosphate; Chloroquini phosphas; NSC-14050; 6E17K3343P; SN-7618; WR-1522; 7-Chloro-4-((4-(diethylamino)-1-methylbutyl)amino)quinoline phosphate (1:2); 1,4-Pentanediamine, N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-, phosphate (1:2); N(4)-(7-Chloro-4-quinolinyl)-N(1),N(1)-diethyl-1,4-pentanediamine, phosphate (1:2)

Frequently Asked Questions

What are the CAS number and molecular formula of Chloroquine Phosphate?

CAS 50-63-5; molecular formula C18H32ClN3O8P2; molecular weight — g/mol.

What other names is Chloroquine Phosphate known by?

Chloroquine diphosphate, Chloroquine phosphate, Aralen phosphate, Resochin, Arechin, Avloclor.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.