喜树碱

Name: 喜树碱
Brand: 济南圣和化工有限公司

CAS 7689-03-4C20H16N2O4MW 348.4

本页收录喜树碱，CAS 登记号为 7689-03-4，分子式 C20H16N2O4，分子量 348.4，归类于医药中间体及原料药。作为主营产品之一，济南圣和化工有限公司可提供从公斤级到吨级的稳定供货，随货附 COA 与质检资料。

产品概览

CAS号	7689-03-4
分子式	C20H16N2O4
分子量	348.4
熔点	275-277 °C
LogP	1.74
纯度	按批次COA提供(不公开发布)
包装	按订单/批次确认(不公开发布)
应用领域	医药中间体及原料药
类别	医药中间体及原料药

应用领域

医药中间体及原料药

喜树碱在医药中间体及原料药领域使用广泛。采购前请确认纯度等级与包装形式，以批次 COA 为验收依据。

包装与储存

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

运输常规化工运输

样品可协商提供

交期现货/按订单安排

供应说明：喜树碱常规包装为按订单/批次确认(不公开发布)，储存时应密封置于阴凉干燥处，避免与氧化剂混放。济南圣和化工有限公司支持国内物流发货，大货交期与运费以订单确认为准。

质量与文件

每批产品随货提供 COA（分析证书）；可按需提供 MSDS/技术数据表及第三方检测报告。纯度与包装以批次 COA 及订单确认为准。

关于供应商

济南圣和化工有限公司位于山东济南，主营化工原料供应，精选产品齐全，覆盖有机化学品、无机化学品、食品添加剂、医药中间体等多个大类。我们随货提供 COA 分析证书，一个工作日内回复报价，欢迎国内外采购方长期合作。

常见问题

喜树碱的 CAS 号是多少？

喜树碱的 CAS 号为 7689-03-4。

该产品的纯度和包装规格是什么？

常规纯度规格为按批次COA提供(不公开发布)，包装为按订单/批次确认(不公开发布)，随货提供 COA。

喜树碱有什么用途？

主要应用于医药中间体及原料药。

如何购买或获取报价？

请发送邮件至 info@591daili.com 或通过 WhatsApp 联系，注明产品名称、CAS 号与需求数量，一个工作日内回复报价。供应商：济南圣和化工有限公司。

PubChem 公开数据

Description

Camptothecin · CAS 7689-03-4 · C20H16N2O4. UNII XT3Z54Z28A. Melting Point: 275-277 °C; LogP: 1.74.

Identification

CAS Registry Number	7689-03-4
PubChem CID	24360
Molecular formula	C20H16N2O4
IUPAC name	(19S)-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
UNII (FDA)	XT3Z54Z28A

Computed Descriptors

Molecular Weight	348.4
XLogP3	1
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	1
Exact Mass	348.11100700
Monoisotopic Mass	348.11100700
Topological Polar Surface Area	79.7
Heavy Atom Count	26
Formal Charge	0

Physical & Chemical Properties

Melting Point	275-277 °C
LogP	1.74

Physical description & handling notes

178.35 Å² [M+K]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
178.86 Å² [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
163.42 Å² [M+H-H2O]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
181.9 Å² [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
Camptothecin demonstrated strong anticancer activity in preliminary clinical trials but also low solubility and adverse drug reaction. Camptothecin is believed to be a potent topoisomerase inhibitor that interferes with the essential function of topoisomerase in DNA replication.

GHS Hazard Classification

Reported hazard statements	H301 (98%), H340 (20%)

H301 (98%): Toxic if swallowed [Danger Acute toxicity, oral]

H340 (20%): May cause genetic defects [Danger Germ cell mutagenicity]

Documented Uses

Investigated for the treatment of cancer.
Agents obtained from higher plants that have demonstrable cytostatic or antineoplastic activity.
Compounds that inhibit the activity of DNA TOPOISOMERASE I.
Camptothecin binds to the topoisomerase I and DNA complex resulting in a ternary complex, stabilizing it and preventing DNA re-ligation and therefore causes DNA damage which results in apoptosis.

Synonyms

camptothecin; Camptothecine; 7689-03-4; (S)-(+)-Camptothecin; (+)-Camptothecin; d-Camptothecin; 20(S)-Camptothecine; (+)-Camptothecine; 21,22-Secocamptothecin-21-oic acid lactone; NSC94600; NSC-94600; DTXSID0030956; (4S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; XT3Z54Z28A; CHEBI:27656; 1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-, (S)-

Frequently Asked Questions

What are the CAS number and molecular formula of Camptothecin?

CAS 7689-03-4; molecular formula C20H16N2O4; molecular weight — g/mol.

What other names is Camptothecin known by?

camptothecin, Camptothecine, 7689-03-4, (S)-(+)-Camptothecin, (+)-Camptothecin, d-Camptothecin.

Is Camptothecin classified as hazardous?

Hazard statements reported: H301, H340.

What are the key physical properties of Camptothecin?

Melting Point: 275-277 °C; LogP: 1.74.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

喜树碱