别嘌呤醇

Description

4-Hydroxypyrazolo[3,4-d]pyrimidine · CAS 315-30-0 · C5H4N4O. UNII 63CZ7GJN5I. Boiling Point: 250.36; Melting Point: >300; Melting Point: 350 °C.

Identification

CAS Registry Number	315-30-0
PubChem CID	135401907
Molecular formula	C5H4N4O
IUPAC name	1,5-dihydropyrazolo[5,4-d]pyrimidin-4-one
UNII (FDA)	63CZ7GJN5I

Computed Descriptors

Molecular Weight	136.11
XLogP3	-0.7
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	0
Exact Mass	136.03851076
Monoisotopic Mass	136.03851076
Topological Polar Surface Area	70.1
Heavy Atom Count	10
Formal Charge	0

Physical & Chemical Properties

Boiling Point	250.36
Melting Point	>300
Melting Point	350 °C
Solubility	In water, 569 mg/L at 25 °C
Solubility	5.88e+00 g/L
LogP	-1.8
LogP	log Kow = -0.55
LogP	-1
LogP	-0.55
Dissociation Constants	10.2 (at 25℃)

Physical description & handling notes

• 4-hydroxypyrazolo(3,4-d)pyrimidine is an odorless tasteless white microcrystalline powder. (NTP, 1992)
• Solid
• FLUFFY WHITE TO OFF-WHITE POWDER
• Crystals
• SLIGHT
• TASTELESS

GHS Hazard Classification

Reported hazard statements	H301 (53.1%), H317 (94.4%)

Documented Uses

• THERAPEUTIC CATEGORY: Treatment of hyperuricemia and chronic gout, antiurolithic.
• Use (kg) in Switzerland (2009): >5000
• Use (kg; approx.) in Germany (2009): >100000
• Use (kg) in France (2004): 54247
• Consumption (g per capita) in Switzerland (2009): 0.64
• Consumption (g per capita; approx.) in Germany (2009): 1.2

Synonyms

allopurinol; 315-30-0; 1H-Pyrazolo[3,4-d]pyrimidin-4-ol; Zyloric; Suspendol; Takanarumin; Allopur; Bloxanth; Uriprim; Xanturat; Urbol; Ketobun-A; Nektrohan; Adenock; Aluline; Dabrosin

Frequently Asked Questions

What are the CAS number and molecular formula of 4-Hydroxypyrazolo[3,4-d]pyrimidine?

CAS 315-30-0; molecular formula C5H4N4O; molecular weight — g/mol.

What other names is 4-Hydroxypyrazolo[3,4-d]pyrimidine known by?

allopurinol, 315-30-0, 1H-Pyrazolo[3,4-d]pyrimidin-4-ol, Zyloric, Suspendol, Takanarumin.

Is 4-Hydroxypyrazolo[3,4-d]pyrimidine classified as hazardous?

Hazard statements reported: H301, H317.

What are the key physical properties of 4-Hydroxypyrazolo[3,4-d]pyrimidine?

Boiling Point: 250.36; Melting Point: >300; Melting Point: 350 °C; Solubility: In water, 569 mg/L at 25 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.