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Berberine

CAS 2086-83-1C20H18NO4+MW 336.4

Berberine (CAS 2086-83-1) — formula C20H18NO4+, molecular weight 336.4; category pharmaceutical intermediates and APIs.

Product Description

Berberine (CAS 2086-83-1) is a chemical raw material in the pharmaceutical intermediates and APIs category. Its molecular formula C20H18NO4+ comprises 20 C, 18 H, 1 N, 4 O atoms. Its molecular weight is about 336.4. Reported physicochemical data: melting point around 145, LogP about 3.6. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.

Product Overview

CAS Number2086-83-1
Molecular FormulaC20H18NO4+
Molecular Weight336.4
Melting Point145
LogP3.6
ApplicationsOccurs naturally in many plants and used in traditional medicine as an antiprotozoal, antimalarial, antibacterial, and antidiarrheal
CategoryPharmaceutical Intermediates & APIs

Applications

Documented applications: Occurs naturally in many plants and used in traditional medicine as an antiprotozoal, antimalarial, antibacterial, and antidiarrheal.

Technical Profile

What this product is

Berberine is a pharmaceutical intermediate or API compound with CAS registry number 2086-83-1 and molecular formula C20H18NO4+ (molecular weight 336.4), belonging to the pharmaceutical intermediates and APIs segment of chemical raw materials.

Identification

CAS number: 2086-83-1

Its molecular formula C20H18NO4+ comprises 20 C, 18 H, 1 N, 4 O atoms.

Also known as: Berberine · 小檗碱

Category: pharmaceutical intermediates and APIs

Frequently Asked Questions

What is the CAS number of Berberine?

The CAS registry number of Berberine is 2086-83-1.

What is the molecular formula and molecular weight of Berberine?

Molecular formula C20H18NO4+, molecular weight 336.4.

What other names is Berberine known by?

It is also registered under: Berberine, 小檗碱.

What are the documented applications of Berberine?

Recorded applications: Occurs naturally in many plants and used in traditional medicine as an antiprotozoal, antimalarial, antibacterial, and antidiarrheal.

Which category does Berberine belong to?

Category: Pharmaceutical Intermediates & APIs.

Packaging & documentation

Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.

PubChem Public Data

Independent reference data for Berberine (CAS 2086-83-1), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number2086-83-1
PubChem CID2353
Molecular formulaC20H18NO4+
IUPAC name16,17-dimethoxy-5,7-dioxa-13-azoniapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(13),2,4(8),9,14,16,18,20-octaene
UNII (FDA)0I8Y3P32UF

Computed descriptors

Molecular Weight336.4
XLogP33.6
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass336.12358306
Monoisotopic Mass336.12358306
Topological Polar Surface Area40.8
Heavy Atom Count25

Physicochemical values on record

Melting Point145
Melting Point145 °C

Documented uses on record

  • Occurs naturally in many plants and used in traditional medicine as an antiprotozoal, antimalarial, antibacterial, and antidiarrheal; [Merck Index]
  • Berberine is a quaternary ammonia compound found in many botanical products, including goldenseal, barberry and Oregon grape, which is used for its purported antioxidant and antimicrobial properties for a host of conditions, including obesity, diabetes, hyperlipidemia, heart failure, H. pylori infection and colonic adenoma prevention. Berberine has not been linked to serum aminotransferase elevations during therapy nor to instances of clinically apparent liver injury.

Synonyms and trade names

berberine; 2086-83-1; Umbellatine; Berberin; Berbericine; Majarine; Thalsine; Umbellatin; Berberone; 0I8Y3P32UF; DTXSID9043857; CHEBI:16118; Benzo(g)-1,3-benzodioxolo(5,6-a)quinolizinium, 5,6-dihydro-9,10-dimethoxy-; Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-; 9,10-dimethoxy-5,6-dihydro[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-7-ium; 9,10-DIMETHOXY-5,6-DIHYDRO(1,3)DIOXOLO(4,5-G)ISOQUINO(3,2-A)ISOQUINOLIN-7-IUM

Regulatory listings held on file

Regulatory & Food ContactBerberine and Weight Loss: What You Need To Know

What the public record says

Berberine · CAS 2086-83-1 · C20H18NO4+. UNII 0I8Y3P32UF. Melting Point: 145; Melting Point: 145 °C.

Source: PubChem / Wikidata; the batch COA governs where values differ.

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