瑞格列奈

Name: 瑞格列奈
Brand: 济南圣和化工有限公司

CAS 135062-02-1C27H36N2O4MW 452.6

本页收录瑞格列奈，CAS 登记号为 135062-02-1，分子式 C27H36N2O4，分子量 452.6，归类于医药中间体及原料药。作为主营产品之一，济南圣和化工有限公司可提供从公斤级到吨级的稳定供货，随货附 COA 与质检资料。

产品概览

CAS号	135062-02-1
分子式	C27H36N2O4
分子量	452.6
熔点	130-131 °C
LogP	5.9
纯度	按批次COA提供(不公开发布)
包装	按订单/批次确认(不公开发布)
应用领域	医药中间体及原料药
类别	医药中间体及原料药

应用领域

医药中间体及原料药

瑞格列奈主要应用于医药中间体及原料药。具体使用工况下的添加量与规格要求，欢迎与技术团队沟通确认。

包装与储存

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

运输常规化工运输

样品可协商提供

交期现货/按订单安排

供货能力：瑞格列奈备有现货，包装形式为按订单/批次确认(不公开发布)。我们支持对公转账并开具增值税发票，山东省内可安排快速配送，省外按物流时效发货，具体请联系 info@591daili.com。

质量与文件

每批产品随货提供 COA（分析证书）；可按需提供 MSDS/技术数据表及第三方检测报告。纯度与包装以批次 COA 及订单确认为准。

关于供应商

济南圣和化工有限公司位于山东济南，主营化工原料供应，精选产品 3,000+ 种，覆盖有机化学品、无机化学品、食品添加剂、医药中间体等 12 大分类。我们随货提供 COA 分析证书，一个工作日内回复报价，欢迎国内外采购方长期合作。

常见问题

瑞格列奈的 CAS 号是多少？

瑞格列奈的 CAS 号为 135062-02-1。

该产品的纯度和包装规格是什么？

常规纯度规格为按批次COA提供(不公开发布)，包装为按订单/批次确认(不公开发布)，随货提供 COA。

瑞格列奈有什么用途？

主要应用于医药中间体及原料药。

如何购买或获取报价？

请发送邮件至 info@591daili.com 或通过 WhatsApp 联系，注明产品名称、CAS 号与需求数量，一个工作日内回复报价。供应商：济南圣和化工有限公司。

PubChem 公开数据

Description

Repaglinide · CAS 135062-02-1 · C27H36N2O4. UNII 668Z8C33LU. Melting Point: 130-131 °C; Melting Point: 130 - 131 °C; Solubility: 2.94e-03 g/L.

Identification

CAS Registry Number	135062-02-1
PubChem CID	65981
Molecular formula	C27H36N2O4
IUPAC name	2-ethoxy-4-[2-[[(1S)-3-methyl-1-(2-piperidin-1-ylphenyl)butyl]amino]-2-oxoethyl]benzoic acid
UNII (FDA)	668Z8C33LU

Computed Descriptors

Molecular Weight	452.6
XLogP3	5.2
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	10
Exact Mass	452.26750763
Monoisotopic Mass	452.26750763
Topological Polar Surface Area	78.9
Heavy Atom Count	33
Formal Charge	0

Physical & Chemical Properties

Melting Point	130-131 °C
Melting Point	130 - 131 °C
Solubility	2.94e-03 g/L
LogP	5.9
LogP	3.2
Dissociation Constants	3.75

Physical description & handling notes

Solid
>67.9 [ug/mL] (The mean of the results at pH 7.4)

GHS Hazard Classification

Reported hazard statements	H361 (96.7%), H362 (98.3%), H412 (93.3%)

H361 (96.7%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

H362 (98.3%): May cause harm to breast-fed children [Reproductive toxicity, effects on or via lactation]

Documented Uses

Use (kg; approx.) in Germany (2009): >100
Consumption (g per capita; approx.) in Germany (2009): 0.00122
As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
Repaglinide is a drug used in the treatment of diabetes mellitus type 2. It belongs to a class of antihyperglycemic agents known as meglitinides, along with nateglinide. Meglitinides work to reduce blood glucose levels by stimulating endogenous insulin production. The present recommended starting dose is dependent on hemoglobin A1c levels, with those below 8% (64 mmol/mol) urged to start with 0.5 mg pre-prandially and those above 8% to start with 1 to 2 mg.
Repaglinide is a benzoic acid derivative that stimulates insulin secretion from the pancreas and is used in the therapy of type 2 diabetes. Repaglinide has been linked to rare instances of clinically apparent acute liver injury.
Breast Feeding; Lactation; Milk, Human; Hypoglycemic Agents

Synonyms

Repaglinide; 135062-02-1; Prandin; Repaglinida; AG-EE 623 ZW; GlucoNorm; AG-EE 388 ZW; Repaglinidum; AGEE-623ZW; enyglid; AG-EE-623ZW; 2-ethoxy-4-[2-[[(1S)-3-methyl-1-(2-piperidin-1-ylphenyl)butyl]amino]-2-oxoethyl]benzoic acid; DTXSID3023552; NSC-759893; AG-EE-623-ZW; A10BX02

Frequently Asked Questions

What are the CAS number and molecular formula of Repaglinide?

CAS 135062-02-1; molecular formula C27H36N2O4; molecular weight — g/mol.

What other names is Repaglinide known by?

Repaglinide, 135062-02-1, Prandin, Repaglinida, AG-EE 623 ZW, GlucoNorm.

Is Repaglinide classified as hazardous?

Hazard statements reported: H361, H362, H412.

What are the key physical properties of Repaglinide?

Melting Point: 130-131 °C; Melting Point: 130 - 131 °C; Solubility: 2.94e-03 g/L; LogP: 5.9.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.