Isotretinoin (CAS 4759-48-2) — formula C20H28O2, molecular weight 300.4; category pharmaceutical intermediates and APIs.
Isotretinoin (CAS 4759-48-2) is a chemical raw material in the pharmaceutical intermediates and APIs category. Its molecular formula C20H28O2 comprises 20 C, 28 H, 2 O atoms. Its molecular weight is about 300.4. Reported physicochemical data: melting point around 372 to 374 °F (NTP, 1992), boiling point around 462.8, LogP about 5.66. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.
| CAS Number | 4759-48-2 |
|---|---|
| Molecular Formula | C20H28O2 |
| Molecular Weight | 300.4 |
| Melting Point | 372 to 374 °F (NTP, 1992) |
| Boiling Point | 462.8 |
| LogP | 5.66 |
| Applications | Dermatologic Agents, Teratogens, MEDICATION, Use (kg, approx.) in Germany (2009): >250, Use (kg) in USA (2002): 1380 |
| Category | Pharmaceutical Intermediates & APIs |
Documented applications: Dermatologic Agents, Teratogens, MEDICATION, Use (kg, approx.) in Germany (2009): >250, Use (kg) in USA (2002): 1380.
Isotretinoin is a pharmaceutical intermediate or API compound with CAS registry number 4759-48-2 and molecular formula C20H28O2 (molecular weight 300.4), belonging to the pharmaceutical intermediates and APIs segment of chemical raw materials.
CAS number: 4759-48-2
Its molecular formula C20H28O2 comprises 20 C, 28 H, 2 O atoms.
Also known as: Isotretinoin · 异维A酸
Category: pharmaceutical intermediates and APIs
The CAS registry number of Isotretinoin is 4759-48-2.
Molecular formula C20H28O2, molecular weight 300.4.
It is also registered under: Isotretinoin, 异维A酸.
Recorded applications: Dermatologic Agents, Teratogens, MEDICATION, Use (kg, approx.) in Germany (2009): >250, Use (kg) in USA (2002): 1380.
Category: Pharmaceutical Intermediates & APIs.
Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.
Independent reference data for Isotretinoin (CAS 4759-48-2), compiled from public chemistry databases.
| CAS Registry Number | 4759-48-2 |
|---|---|
| PubChem CID | 5282379 |
| Molecular formula | C20H28O2 |
| IUPAC name | (2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid |
| UNII (FDA) | EH28UP18IF |
| Molecular Weight | 300.4 |
|---|---|
| XLogP3 | 6.3 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 5 |
| Exact Mass | 300.208930132 |
| Monoisotopic Mass | 300.208930132 |
| Topological Polar Surface Area | 37.3 |
| Heavy Atom Count | 22 |
| Boiling Point | 462.8 |
|---|---|
| Melting Point | 372 to 374 °F (NTP, 1992) |
| Melting Point | 189-190 |
| Melting Point | 174-175 °C |
| Solubility | 0.00477mg/mL |
| LogP | 5.66 |
| Dissociation Constants | 5.15 |
| Dissociation Constants | ~4 |
Isotretinoin; 13-cis-Retinoic acid; 4759-48-2; Accutane; 13-cis-Vitamin A acid; Neovitamin A acid; Claravis; Roaccutane; 13-cis retinoic acid; Amnesteem; Isotrex; Sotret; Isotretinoine; Roaccutan; Teriosal; isotretinoino
| Reported hazard statements | H315 (30.7%), H319 (31.4%), H335 (30.1%), H360 (100%), H400 (71.2%), H410 (71.9%) |
|---|
H315 (30.7%): Causes skin irritation [Warning Skin corrosion/irritation]
H319 (31.4%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
Isotretinoin · CAS 4759-48-2 · C20H28O2. UNII EH28UP18IF. Boiling Point: 462.8; Melting Point: 372 to 374 °F (NTP, 1992); Melting Point: 189-190.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 异维A酸