Epirizole

Description

Epirizole · CAS 18694-40-1 · C11H14N4O2. UNII 3B46O2FH8I. Melting Point: 90-92; LogP: 1.35.

Identification

CAS Registry Number	18694-40-1
PubChem CID	3242
Molecular formula	C11H14N4O2
IUPAC name	4-methoxy-2-(5-methoxy-3-methylpyrazol-1-yl)-6-methylpyrimidine
UNII (FDA)	3B46O2FH8I

Computed Descriptors

Molecular Weight	234.25
XLogP3	1.3
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	3
Exact Mass	234.11167570
Monoisotopic Mass	234.11167570
Topological Polar Surface Area	62.1
Heavy Atom Count	17
Formal Charge	0

Physical & Chemical Properties

Melting Point	90-92
LogP	1.35

Physical description & handling notes

• >35.1 [ug/mL] (The mean of the results at pH 7.4)

GHS Hazard Classification

Reported hazard statements	H302 (100%), H312 (100%), H315 (100%), H319 (100%), H332 (100%), H335 (100%)

Documented Uses

• Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.

Synonyms

epirizole; Mepirizole; 18694-40-1; Mebron; Methopyrimazole; 4-Methoxy-2-(5-methoxy-3-methyl-1H-pyrazol-1-yl)-6-methylpyrimidine; DA-398; 4-Methoxy-2-(5-methoxy-3-methylpyrazol-1-yl)-6-methylpyrimidine; DTXSID4045422; 3B46O2FH8I; Pyrimidine, 4-methoxy-2-(5-methoxy-3-methyl-1H-pyrazol-1-yl)-6-methyl-; DTXCID2025422; RefChem:590943; 242-507-1; Mepirizol; Epirizolum [INN-Latin]

Frequently Asked Questions

What are the CAS number and molecular formula of Epirizole?

CAS 18694-40-1; molecular formula C11H14N4O2; molecular weight — g/mol.

What other names is Epirizole known by?

epirizole, Mepirizole, 18694-40-1, Mebron, Methopyrimazole, 4-Methoxy-2-(5-methoxy-3-methyl-1H-pyrazol-1-yl)-6-methylpyrimidine.

Is Epirizole classified as hazardous?

Hazard statements reported: H302, H312, H315, H319, H332.

What are the key physical properties of Epirizole?

Melting Point: 90-92; LogP: 1.35.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.